BIO 116 Psych and Behavioral Health EOR Study Guide- Luther College

1) Bipolar I Disorder a. RF: FHx/1st-degree relative is strongest RF, men = women b. 1% of population, avg age of onset is 20s-30s, new onset is rare after 50 yrs c. The earlier the onset, the greater likelihood of psychotic features & the poorer the prognosis d. Diagnostic Criteria: i. At least 1 manic or mixed episode (only requirement) – manic episodes often cycle with occasional depressive episodes but major depressive episodes are not required for the dx ii. Mania = abnormal & persistently elevated, expansive or irritable mood at least 1 week (or less if hospitalization is required) with marked impairment of social occupation/function 1. At least 3: a. Mood – euphoria, irritable, labile or dysphoric b. Thinking – racing, flight of ideas, disorganized, easily distracted, expansive or grandiose thoughts (highly inflated self esteem), impaired judgement c. Behavior – physical hyperactivity, pressured speech, decreased need for sleep, increased impulsivity, excessive involvement in pleasurable activities including risk-taking, hypersexuality, disinhibition & increased goal directed activity iii. Psychotic symptoms (paranoia, delusions, hallucinations) may be seen iv. Sx not due to a medical condition or substance use e. Management: i. Mood Stabilizers: Lithium is 1st line