Chapter 01: An Overview of Immunology
Turgeon: Evolve Resources for Immunology & Serology in Laboratory Medicine, 6th Edition
MULTIPLE CHOICE
1. The “father” of immunology is generally considered to be
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B
Louis Pasteur is generally considered to be the “father of immunology.”
DIF: Cognitive Level: I REF: p. 3
2. An early form of immunization was practiced by the
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans.
ANS: C
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried powders de
smallpox lesions.
DIF: Cognitive Level: I REF: p. 2
3. A specific function of the immune system is to
a. recognize self from nonself.
b. defend the body against nonself.
c. amplify specific functions.
d. Both A and B.
ANS: D
The function of the immune system is to recognize self from nonself and defend the body against nons
necessary for survival. The immune system also has nonspecific effector mechanisms that usually amp
Nonspecific components of the immune system include mononuclear phagocytes, polymorphonuclear
factors (e.g., complement).
DIF: Cognitive Level: I REF: p. 3
4. An undesirable consequence of immunity is
a. natural resistance.
b. acquired resistance to infectious diseases.
c. an autoimmune disorder.
d. recovery from infectious disease.
ANS: C
The desirable consequences of immunity include natural resistance, recovery, and acquired resistance t
deficiency or dysfunction of the immune system can cause many disorders. Undesirable consequences
rejection of a transplanted organ, or an autoimmune disorder.
DIF: Cognitive Level: I REF: p. 3
5. The first line of defense against infection is
a. unbroken skin or mucous membranes.
b. phagocytosis.
c. antibody production.
, 7. A specific component of the adaptive immune system formed in response to antigenic stimulation is
a. complement.
b. immunoglobulin.
c. increased secretion of mucus.
d. enhanced phagocytosis.
ANS: B
If specific antibodies have been formed to antigenic stimulation, they are available to protect the body
The recognition of foreign substances and subsequent production of antibodies to these substances defi
DIF: Cognitive Level: I REF: p. 7
8. Acquired immunity can result from
a. vaccination by injection of an antigen.
b. contracting a disease.
c. genetic inheritance.
d. Both A and B.
ANS: D
Antibody-mediated immunity to infection can be acquired if the antibodies are formed by the host or if
another source; these two types of acquired immunity are called active immunity and passive immunity
DIF: Cognitive Level: I REF: p. 7
9. A child who contracts a contagious disease from an older sibling could develop __________________
disease.
a. natural active
b. artificial active
c. natural passive
d. artificial passive
ANS: A
Active immunity can be acquired by natural exposure in response to an infection or natural series of in
intentional injection of an antigen.
DIF: Cognitive Level: II REF: p. 7
10. Preschool children who are vaccinated against specific microorganisms would be expected to develop
immunity against those microorganisms.
a. natural active
b. artificial active
c. natural passive
d. artificial passive
ANS: B
Vaccination is an effective artificial method of stimulating antibody production and memory (acquired
contracting the disease.
DIF: Cognitive Level: I REF: p. 7
11. Artificial passive immunity is achieved by
a. vaccination.
b. contracting a disease.
c. infusion or injection of preformed specific antibody.
d. transfer in vivo.
ANS: C
Artificial passive immunity is achieved by infusion of serum or plasma containing high concentrations
from an actively immunized individual. Passive immunity via preformed antibodies in serum provides
antibody protection against microorganisms (e.g., hepatitis A) by administering preformed antibodies.
Turgeon: Evolve Resources for Immunology & Serology in Laboratory Medicine, 6th Edition
MULTIPLE CHOICE
1. The “father” of immunology is generally considered to be
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B
Louis Pasteur is generally considered to be the “father of immunology.”
DIF: Cognitive Level: I REF: p. 3
2. An early form of immunization was practiced by the
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans.
ANS: C
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried powders de
smallpox lesions.
DIF: Cognitive Level: I REF: p. 2
3. A specific function of the immune system is to
a. recognize self from nonself.
b. defend the body against nonself.
c. amplify specific functions.
d. Both A and B.
ANS: D
The function of the immune system is to recognize self from nonself and defend the body against nons
necessary for survival. The immune system also has nonspecific effector mechanisms that usually amp
Nonspecific components of the immune system include mononuclear phagocytes, polymorphonuclear
factors (e.g., complement).
DIF: Cognitive Level: I REF: p. 3
4. An undesirable consequence of immunity is
a. natural resistance.
b. acquired resistance to infectious diseases.
c. an autoimmune disorder.
d. recovery from infectious disease.
ANS: C
The desirable consequences of immunity include natural resistance, recovery, and acquired resistance t
deficiency or dysfunction of the immune system can cause many disorders. Undesirable consequences
rejection of a transplanted organ, or an autoimmune disorder.
DIF: Cognitive Level: I REF: p. 3
5. The first line of defense against infection is
a. unbroken skin or mucous membranes.
b. phagocytosis.
c. antibody production.
, 7. A specific component of the adaptive immune system formed in response to antigenic stimulation is
a. complement.
b. immunoglobulin.
c. increased secretion of mucus.
d. enhanced phagocytosis.
ANS: B
If specific antibodies have been formed to antigenic stimulation, they are available to protect the body
The recognition of foreign substances and subsequent production of antibodies to these substances defi
DIF: Cognitive Level: I REF: p. 7
8. Acquired immunity can result from
a. vaccination by injection of an antigen.
b. contracting a disease.
c. genetic inheritance.
d. Both A and B.
ANS: D
Antibody-mediated immunity to infection can be acquired if the antibodies are formed by the host or if
another source; these two types of acquired immunity are called active immunity and passive immunity
DIF: Cognitive Level: I REF: p. 7
9. A child who contracts a contagious disease from an older sibling could develop __________________
disease.
a. natural active
b. artificial active
c. natural passive
d. artificial passive
ANS: A
Active immunity can be acquired by natural exposure in response to an infection or natural series of in
intentional injection of an antigen.
DIF: Cognitive Level: II REF: p. 7
10. Preschool children who are vaccinated against specific microorganisms would be expected to develop
immunity against those microorganisms.
a. natural active
b. artificial active
c. natural passive
d. artificial passive
ANS: B
Vaccination is an effective artificial method of stimulating antibody production and memory (acquired
contracting the disease.
DIF: Cognitive Level: I REF: p. 7
11. Artificial passive immunity is achieved by
a. vaccination.
b. contracting a disease.
c. infusion or injection of preformed specific antibody.
d. transfer in vivo.
ANS: C
Artificial passive immunity is achieved by infusion of serum or plasma containing high concentrations
from an actively immunized individual. Passive immunity via preformed antibodies in serum provides
antibody protection against microorganisms (e.g., hepatitis A) by administering preformed antibodies.
