Lesson 08 - Osteoarthritis and Total Knee Replacement : NRSG2570: Multisystem Disorders (1B-A_2020-02-24_Miramar) 4/7/20, 6)55 PM
Lesson 08 - Osteoarthritis and Total Knee Replacement
Due Apr 7 at 11:59pm Points 40 Questions 40
Available Mar 18 at 12am - Apr 7 at 11:59pm 21 days Time Limit None
Attempt History
Attempt Time Score
LATEST Attempt 1 849 minutes 2.5 out of 40 *
* Some questions not yet graded
Score for this quiz: 2.5 out of 40 *
Submitted Apr 7 at 1:25pm
This attempt took 849 minutes.
Question 1 Not yet graded / 1 pts
Exercise 1 - Writing Activity
This exercise will take approximately 15 minutes to complete.
Exercise 1 - Question 1
Briefly describe the pathophysiology of OA. (Hint: See Chapter 18 in
your textbook.)
Your Answer:
The pathophysiology of Osteoarthritis involves a degradation of
cartilage and remodeling of bone due to an active response of
chondrocytes in the articular cartilage and the inflammatory cells in the
surrounding tissues
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, Lesson 08 - Osteoarthritis and Total Knee Replacement : NRSG2570: Multisystem Disorders (1B-A_2020-02-24_Miramar) 4/7/20, 6)55 PM
OA is characterized by progressive deterioration and loss of
cartilage in one or more joints (articular cartilage). The normal
bluish-white, translucent cartilage becomes opaque and yellow-
brown in color. As cartilage and the bone beneath the cartilage
begin to erode, the joint space narrows and osteophytes (bone
spurs) form. Fissures, calcifications, and ulcerations develop
and the cartilage thins. Inflammatory cytokines enhance tissue
deterioration. Weight-bearing joints (hips and knees), the
vertebral column, and the hands are primarily affected because
they are used most often or bear the mechanical stress of body
weight.
Question 2 0. pts
Exercise 1 - Question 2
Which are considered to be causative factors related to the occurrence
of primary osteoarthritis? Select all that apply.
Correct Answer Aging
Correct!
Genetic changes
Correct!
Obesity
Correct! Joint trauma
You Answered Autoimmune factors
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,Lesson 08 - Osteoarthritis and Total Knee Replacement : NRSG2570: Multisystem Disorders (1B-A_2020-02-24_Miramar) 4/7/20, 6)55 PM
Medication usage
Question 3 Not yet graded / 1 pts
Exercise 1 - Question 3
What are the clinical manifestations of OA?
Your Answer:
Clinical manifestations of Osteoarthritis are joint pain, stiffness, and
locomotor restriction. Other manifestations can include muscle
weakness, poor balance, and fibromyalgia
Chronic joint pain and stiffness
Crepitus
Enlarged, hard joints
Heberden’s nodes
Bouchard’s nodes
Joint effusions
Loss of function
Muscle atrophy from disuse secondary to pain
Loss of function/decreased mobility
Question 4 Not yet graded / 1 pts
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, Lesson 08 - Osteoarthritis and Total Knee Replacement : NRSG2570: Multisystem Disorders (1B-A_2020-02-24_Miramar) 4/7/20, 6)55 PM
Exercise 1 - Question 4
What laboratory and/or radiographic testing is used in the diagnosis of
OA? (Hint: See Chapter 18 in your textbook.)
Your Answer:
Magnetic Resonance Imaging (MRI)
Erythrocyte sedimentation rate (ESR); normal or slightly
elevated with OA
High-sensitivity C-reactive protein; normal or slightly elevated
with OA
X-rays; structural joint changes
Magnetic resonance imaging (MRI); determine vertebral or
knee involvement
Question 5 Not yet graded / 1 pts
Exercise 1 - Question 5
How do primary and secondary osteoarthritis differ?
Your Answer:
Primary osteoarthritis, also known as idiopathic, affects joints of one
site with no known cause. Secondary osteoarthritis affects a joint of one
site and is due to some external or internal injury or disease
https://concorde.instructure.com/courses/27651/quizzes/132251?module_item_id=2243393 Page 4 of 34
Lesson 08 - Osteoarthritis and Total Knee Replacement
Due Apr 7 at 11:59pm Points 40 Questions 40
Available Mar 18 at 12am - Apr 7 at 11:59pm 21 days Time Limit None
Attempt History
Attempt Time Score
LATEST Attempt 1 849 minutes 2.5 out of 40 *
* Some questions not yet graded
Score for this quiz: 2.5 out of 40 *
Submitted Apr 7 at 1:25pm
This attempt took 849 minutes.
Question 1 Not yet graded / 1 pts
Exercise 1 - Writing Activity
This exercise will take approximately 15 minutes to complete.
Exercise 1 - Question 1
Briefly describe the pathophysiology of OA. (Hint: See Chapter 18 in
your textbook.)
Your Answer:
The pathophysiology of Osteoarthritis involves a degradation of
cartilage and remodeling of bone due to an active response of
chondrocytes in the articular cartilage and the inflammatory cells in the
surrounding tissues
https://concorde.instructure.com/courses/27651/quizzes/132251?module_item_id=2243393 Page 1 of 34
, Lesson 08 - Osteoarthritis and Total Knee Replacement : NRSG2570: Multisystem Disorders (1B-A_2020-02-24_Miramar) 4/7/20, 6)55 PM
OA is characterized by progressive deterioration and loss of
cartilage in one or more joints (articular cartilage). The normal
bluish-white, translucent cartilage becomes opaque and yellow-
brown in color. As cartilage and the bone beneath the cartilage
begin to erode, the joint space narrows and osteophytes (bone
spurs) form. Fissures, calcifications, and ulcerations develop
and the cartilage thins. Inflammatory cytokines enhance tissue
deterioration. Weight-bearing joints (hips and knees), the
vertebral column, and the hands are primarily affected because
they are used most often or bear the mechanical stress of body
weight.
Question 2 0. pts
Exercise 1 - Question 2
Which are considered to be causative factors related to the occurrence
of primary osteoarthritis? Select all that apply.
Correct Answer Aging
Correct!
Genetic changes
Correct!
Obesity
Correct! Joint trauma
You Answered Autoimmune factors
https://concorde.instructure.com/courses/27651/quizzes/132251?module_item_id=2243393 Page 2 of 34
,Lesson 08 - Osteoarthritis and Total Knee Replacement : NRSG2570: Multisystem Disorders (1B-A_2020-02-24_Miramar) 4/7/20, 6)55 PM
Medication usage
Question 3 Not yet graded / 1 pts
Exercise 1 - Question 3
What are the clinical manifestations of OA?
Your Answer:
Clinical manifestations of Osteoarthritis are joint pain, stiffness, and
locomotor restriction. Other manifestations can include muscle
weakness, poor balance, and fibromyalgia
Chronic joint pain and stiffness
Crepitus
Enlarged, hard joints
Heberden’s nodes
Bouchard’s nodes
Joint effusions
Loss of function
Muscle atrophy from disuse secondary to pain
Loss of function/decreased mobility
Question 4 Not yet graded / 1 pts
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, Lesson 08 - Osteoarthritis and Total Knee Replacement : NRSG2570: Multisystem Disorders (1B-A_2020-02-24_Miramar) 4/7/20, 6)55 PM
Exercise 1 - Question 4
What laboratory and/or radiographic testing is used in the diagnosis of
OA? (Hint: See Chapter 18 in your textbook.)
Your Answer:
Magnetic Resonance Imaging (MRI)
Erythrocyte sedimentation rate (ESR); normal or slightly
elevated with OA
High-sensitivity C-reactive protein; normal or slightly elevated
with OA
X-rays; structural joint changes
Magnetic resonance imaging (MRI); determine vertebral or
knee involvement
Question 5 Not yet graded / 1 pts
Exercise 1 - Question 5
How do primary and secondary osteoarthritis differ?
Your Answer:
Primary osteoarthritis, also known as idiopathic, affects joints of one
site with no known cause. Secondary osteoarthritis affects a joint of one
site and is due to some external or internal injury or disease
https://concorde.instructure.com/courses/27651/quizzes/132251?module_item_id=2243393 Page 4 of 34