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7/22/11
, Gastrointestinal Tract infections
Click to edit Master subtitle style
7/22/11
, Diarrhea
Increase in fluid and electrolyte loss into the lumen of the gut
• Gastroenteritis
– nausea, vomiting & diarrhea
– May also present with abdominal discomfort, cramps, & fever
– Common causes
• Campylobacter jejuni
• E.coli
• Salmonella spp.
• Viruses: Rota
– Rarer causes
• Bacillus cereus
• Clostridium perfringens
• Food poisoning
– Disease caused by ingestion of food contaminated with a toxin
7/22/11
• Dysentery
, Pathogenesis
• Preformed toxins
– Present with short incubation with vomiting
–
C. botulinum and Staph. aureus
• Toxins produced in the gut
– Longer incubation period with marked vomiting
–
V. cholerae and Enterotoxigenic E. coli
• Tissue invasion
–
Entoamoeba histolytica, Salmonella spp., Enteroinvasive
E. coli
• Parasitism
– Protozoa and worms
7/22/11
7/22/11
, Gastrointestinal Tract infections
Click to edit Master subtitle style
7/22/11
, Diarrhea
Increase in fluid and electrolyte loss into the lumen of the gut
• Gastroenteritis
– nausea, vomiting & diarrhea
– May also present with abdominal discomfort, cramps, & fever
– Common causes
• Campylobacter jejuni
• E.coli
• Salmonella spp.
• Viruses: Rota
– Rarer causes
• Bacillus cereus
• Clostridium perfringens
• Food poisoning
– Disease caused by ingestion of food contaminated with a toxin
7/22/11
• Dysentery
, Pathogenesis
• Preformed toxins
– Present with short incubation with vomiting
–
C. botulinum and Staph. aureus
• Toxins produced in the gut
– Longer incubation period with marked vomiting
–
V. cholerae and Enterotoxigenic E. coli
• Tissue invasion
–
Entoamoeba histolytica, Salmonella spp., Enteroinvasive
E. coli
• Parasitism
– Protozoa and worms
7/22/11