NSG 6005 Week 2 Quiz / NSG6005 Week 2 Quiz : South University

  Week 2 QUIZ 1. Question : Drugs that use CYP3A4 isoenzymes for metabolism may: Student Answer: Induce the metabolism of another drug Inhibit the metabolism of another drug Both A and B Neither A nor B Points Received: 0 of 2.5 Comments: Question 2.Question : The route of excretion of a volatile drug will likely be: Student Answer: The kidneys The lungs The bile and feces The skin Points Received: 0 of 2.5 Comments: Question 3.Question : The type of ADR that is the result of an unwanted but otherwise normal pharmacological action of a drug given in the usual therapeutic doses is: Student Answer: Type A Type B Type C Type D Points Received: 0 of 2.5 Comments: Question 4.Question : Patients with psychiatric illnesses have adherence rates to their drug regimen between 35% and 60%. To improve adherence in this population, prescribe drugs: Student Answer: With a longer half-life so that missed doses produce a longer taper on the drug curve In oral formulations that are more easily taken That do not require frequent monitoring Combined with patient education about the need to adhere even when symptoms are absent Question 5.Question : The angiotensin converting enzyme (ACE) inhibitor lisinopril is a known teratogen. Teratogens cause Type ADR. Student Answer: A B C D Points Received: 0 of 2.5 Comments: Question 6.Question : A patient may develop neutropenia from using topical Silvadene for burns. Neutropenia is: Student Answer: A cytotoxic hypersensitivity reaction An immune complex hypersensitivity An immediate hypersensitivity reaction A delayed hypersensitivity reaction Points Received: 0 of 2.5 Comments: Question 7.Question : Genetic testing for VCORC1 mutation to assess potential warfarin resistance is required prior to prescribing warfarin. Student Answer: True False Points Received: 0 of 2.5 Comments: Question 8.Question : Drugs that have a significant first-pass effect: Student Answer: Must be given by the enteral (oral) route only Bypass the hepatic circulation Are rapidly metabolized by the liver and may have little if any desired action Are converted by the liver to more active and fat-soluble forms Points Received: 0 of 2.5 Comments: Question 9.Question : Common OTC pain relievers such as acetaminophen or ibuprofen: Student Answer: Are always safer for the patient than prescription pain medication Are harmful if taken in higher-than-recommended amounts Have minimal interaction with prescription medications Should never be given to children unless recommended by their provider Points Received: 2.5 of 2.5 Comments: Question 10.Question : Factors that affect gastric drug absorption include: Student Answer: Liver enzyme activity Protein-binding properties of the drug molecule Lipid solubility of the drug Ability to chew and swallow Points Received: 2.5 of 2.5 Comments: Question 11.Question : An advantage of prescribing a sublingual medication is that the medication is: Student Answer: Absorbed rapidly Excreted rapidly Metabolized minimally Distributed equally Points Received: 2.5 of 2.5 Comments: Question 12.Question : The major reason for not crushing a sustained release capsule is that, if crushed, the coated beads of the drugs could possibly result in: Student Answer: Disintegration Toxicity Malabsorption Deterioration Points Received: 2.5 of 2.5 Comments: Question 13.Question : A patient’s nutritional intake and lab work reflect hypoalbuminemia. This is critical to prescribing because: Student Answer: Distribution of drugs to target tissue may be affected The solubility of the drug will not match the site of absorption There will be less free drug available to generate an effect Drugs bound to albumin are readily excreted by the kidney Points Received: 0 of 2.5 Comments: Question 14.Question : Warfarin resistance may be seen in patients with VCORC1 mutation, leading to: Student Answer: Toxic levels of warfarin building up Decreased response to warfarin Increased risk for significant drug interactions with warfarin Less risk of drug interactions with warfarin Points Received: 0 of 2.5 Comments: Question 15.Question : Which one of the following statements about bioavailability is true? Student Answer: Bioavailability issues are especially important for drugs with narrow therapeutic ranges or sustained release mechanisms. All brands of a drug have the same bioavailability. ͏ Drugs that are administered more than once a day have greater bioavailability than drugs given once daily. Combining an active drug with an inert substance does not affect bioavailability. Points Received: 0 of 2.5 Comments: Question 16.Question : The first step in the prescribing process according to the World Health Organization is: Student Answer: Choosing the treatment Educating the patient about the medication Diagnosing the patient’s problem Starting the treatment Points Received: 2.5 of 2.5 Comments: Question 17.Question : Carbamazepine has a black box warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy due to: Student Answer: Decreased effectiveness of carbamazepine in treating seizures in Asian patients with the HLA-B*1502 allele Increased risk for drug interactions in Asian patients with the HLA-B*1502 allele Increased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 allele Patients who have the HLA-B*1502 allele being more likely to have a resistance to carbamazepine Points Received: 0 of 2.5 Comments: Question 18.Question : When obtaining a drug history from Harold, he gives you a complete list of his prescription medications. He denies taking any other drugs, but you find that he occasionally takes aspirin for his arthritis flare-ups. This is an example of: Student Answer: His appropriately only telling you about his regularly prescribed medications His hiding information regarding his inappropriate use of aspirin from you A common misconception that intermittently taken OTC medications are not an important part of his drug history A common misuse of OTC aspirin