ATI Pharmacology Proctored Exam Remediation ALL ANSWERS 100% CORRECT GUARANTEE GRADE A+

1. Nephrotoxicity may occur with a number of medications but primarily with certain antimicrobials and NSAIDs. Damage to the kidneys may interfere with medication excretion, leading to accumulation and adverse effects. Aminoglycosides injure cells in the renal tubules of the kidney. Serum creatinine and BUN should be monitored. 2. Anticholinergic effects are due to muscarinic receptor blockade so most effects are seen in the eyes, smooth muscle, exocrine glands and the heart. 3. Vancomyocin adverse effects can included ototoxicity and renal toxicity. When vancomyocin is being used, I and O and kidney function tests need to be monitored. 4. Adverse effects of penicillins include hyperkalemia/dysrhythmias (high doses of penicillin G potassium) and hypernatremia (IV ticarcillin) 5. Penicillins are ontraindicated in patients with renal impairment 6. Cephalosporins are more likely to reach spinal fluid – indicated for use with meningitis 7. Bleeding tendencies exist with the use of cefotetan and ceftriaxone, admin with Vit. K, but avoid using in patients who have known bleeding disorders or are on anticoags. 8. EPS may occur w/in a few hours or can take months to develop. Most often associated with meds affecting the CNS used to treat mental health disorders. Psychosocial integrity (optional if score was above 73%) chapter 7 1. Sedative hypnotic anxiolytic benzodiazepines: enhance the inhibitory effects of GABA in the CNS which gives relief rapidly after administration. 2. In the case of oral toxicity of benzos, use gastric lavage followed by activated charcoal or saline cathartics. 3. Buspirone (BuSpar) – Binds to serotonin and dopamine receptors. Dependency is much less likely than with other anxiolytics, and does not result in sedation or potentiate the effects of other CNS depressants. Used in panic, social anxiety, and OCD.