PHARM 2407-Med-tracker Week 3

PHARM 2407-Med-tracker Week 3 Med-tracker Week 3 Drug: Aspirin Anti-inflammatory Non-opiod analgesic Type: NSAID salicylate Use: pain, fever, decrease platelet aggregation Medication Examples: Aspirin, acetylsalicylic acid, ASA Administration: PO, Rectal Action: Blocks pain impulses in the CNS, reduces inflammation by inhibition of prostaglandin synthesis, antipyretication from vasodilation of peripheral vessels, decrease platelet aggregation. Adverse effects: tinnitus (ototoxic), dizziness, seizures, coma confusion, gastric distress, PUD hepatotoxic, hepatitis, leukopenia, neutropenia, laryngeal edema Contraindications: 3 rd trimester of pregnancy GI bleed, bleeding disorders, PUD Vit K deficiencies, increase ICP, brain bleed Medication/Food interactions: prunes, raisins, licorice, spices contain salicylates Anticoagulants: fish oil= increased bleeding Diuretics, ACE inhibitors, beta blockers = lowered drug effect Nursing interventions: monitor levels monitor bleeding times, Pt/INR, CBC monitor K+ levels, cholesterol, T3 and T4, glucose, and Na+ = may decrease levels, Check I/O monitor peripheral edema. Client education: do not take with other NSAIDS, do not give to a child with flu or virus symptoms (reye syndrome) Take with food and full glass of water, report signs of Toxicity, visual changes, allergic reaction, Avoid ETOH Drug: Ibuprofen NSAID, Analgesic (nonopioid), Propionic acid derivative Pregnancy Category B, Pregnancy Category D (third trimester) Medication Examples: Advil, Caldolor, Children’s advil, Children’s motrin Jr. strength, Excedrin IB, Ibuprofen, Ibuprohm, ibutab, infant’s advil, Midol, Motrin IB cramp Formula maximum strength, motrin migraine pain, pamprin Ibuprofen formula, profen, Tab-Profen Administration: PO, IV Action: May inhibit prostaglandin synthesis, to produce anti-inflammatory, analgesic, and antipyretic effects. Adverse effects: CNS: dizziness, headache, nervousness CV: edema, fluid retention, EENT: Tinnitus GI: abdominal pain, bloating, constipation, decreased appetite, diarrhea, dyspepsia, epigastric distress, flatulence, heartburn, nausea, non-necrotizing enterocolitis, vomiting GU: acute renal failure, azotemia, cystitis, hematuria Hematologic: agranulocytosis, aplastic anemia, leukopenia, neutropenia, pancytopenia, thrombocytopenia, anemia, prolonged bleeding time. Metabolic: hypokalemia, hypoglycemia. Skin: pruritus, rash Contraindications: pt with hypersensitivity to the drug, pt with angioedema, syndrome of nasal polyps, or bronchospastic reaction to aspirin or other NSAIDS. Contraindicated for the treatment of perioperative pain after CABG surgery. Use carefully during pregnancy, and in elderly pt because of GI disorders, history of peptic ulcer disease, hepatic or renal disease, cardiac decomposition, hypertension, asthma, or intrinsic coagulation defects. Active peptic ulcer; hypersensitivity. Neonates with congenital heart disease, suspected necrotising enterocolitis and active bleeding (parenteral). Medication/Food interactions: Anticholinergics (warfarin): Increases risk for GI bleed, Antihypertensive, furosemide, thiazide diuretics: may decrease the effectiveness of diuretics or antihypertensive. Monitor pt closely. Aspirin, corticosteroids, cyclosporine, digoxin, lithium, oral anticoagulants, methotrexate Drug-Herbals: dong quai, feverfew, garlic, ginger, ginkgo biloba, horse chestnut, red clover, may increase risk of bleeding. White willow: her and drug contains similar components Druglifestyle: alcohol use may cause adverse GI reactions. Sun exposure: may cause photosensitivity reactions Nursing interventions: BLACK BOX WARNING: Be aware that patient may be at increased risk of CV event, GI bleeding, monitor accordingly. Administer drug with food or after meals if GI upset occurs. Arrange for periodic ophthalmologic examination during long-term therapy. Discontinue drug if eye changes, symptoms of hepatic impairment, or renal impairment occur. WARNING: Institute emergency procedures if overdose occurs: Gastric lavage, induction of emesis, and supportive therapy. Client education: Use drug only as suggested; avoid overdose. Take the drug with food or after meals if GI upset occurs. Do not exceed the prescribed dosage.Avoid over-the-counter drugs. Many of these drugs contain similar medications, and serious overdosage can occur.You may experience these side effects: Nausea, GI upset, dyspepsia (take drug with food); diarrhea or constipation; drowsiness, dizziness, vertigo, insomnia (use caution when driving or operating dangerous machinery).Report sore throat, fever, rash, itching, weight gain, swelling in ankles or fingers, changes in vision, black or tarry stools. Drug: Celecoxib Classification: NSAID, Anal