NUR-641E Final Exam (Latest 2026/2027 Update) Advanced Pathophysiology and Pharmacology Questions with Verified Answers | 100% Correct | GCU.

NUR-641E Final Exam (Latest 2026/2027
Update) Advanced Pathophysiology and
Pharmacology Questions with Verified
Answers | 100% Correct | GCU.
Question:
What does pharmacokinetics involve??
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Answer:
absorption, distribution, metabolism, excretion
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Question:

What is absorption??
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Answer:

from the administration site either directly or indirectly into the blood
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plasma




Question:

What is distribution??
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Answer:

,reversibly or irreversibly move from the bloodstream into the interstitial
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and intracellular fluid
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Question:
What is metabolism??
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Answer:

Biotransformed via hepatic metabolism or by other tissues
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Question:
What is elimination??
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Answer:

The drug and it metabolites are eliminated from the body
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Question:
What route of administration has the highest bioavailability??
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Answer:

intravenous




Question:

,Which route of administration avoid first-pass metabolism in the liver??
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Answer:

intravenous route i,-




Question:

What administration route has variable and erractic absorption??
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Answer:

rectal




Question:

When is a steady state of a drug reached??
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Answer:
within 4-5 half-lives of a drug
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Question:

What is important to know in regards to half-life??
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Answer:

determines how frequently the drug must be administered
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Predicts how long toxic effects last
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, Question:

What does first-order (linear) pharmacoknetics mean??
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Answer:

the metabolism is directly proportional to the free concentration of the
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drug




Question:

What does zero-order (nonlinear) pharmacokinetics??
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Answer:
a drug is metabolized at a constant rate per unit time
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Question:
What does the drug development proccess involve according to the FDA??
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Answer:
discovery i,-




preclinical research with animal testing
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Phase 1 i,-




Phase 2 i,-




Phase 3 i,-




FDA review of the results to determine approval
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