MMSC433 Hematology 2 Exam 2
Questions & Answers (Grade A+)
The most common clinical application of flow cytometry is:
a. detection of fetomaternal hemorrhage
b. diagnosis of platelet disorders
c. differentiation of anemias
d. diagnosis of leukemias and lymphomas -
correct answer ✅D
Which of the following would be an unexpected finding in
homozygous beta0 thalassemia?
a. normal Hb F
b. bone marrow erythroid hyperplasia
c. target cells
d. severe anemia -
correct answer ✅A
a 13 yr old African American girl, was admitted to the hospital
appearing acutely ill with fever and abdominal pain. On physical
exam, an enlarged spleen was evident. Lab results were as follows:
Hgb 5 g/dL, Hct 15%, RBC 1.4 x 1012/L, WBC 2.2 x 109/L,
Reticulocyte count 1%, Segs 62%, bands 12%, lymphocytes 19%,
Monocytes 4%, Eosinophils 2%, basophils 1%, MCV 92%, MCHC
33%, Platelet count 400 x 109/L. Hemoglobin electrophoresis at
, MMSC433 Hematology 2 Exam 2
Questions & Answers (Grade A+)
alkaline pH showed one band in the HgbS position and one band in
the Hgb C position. The hemoglobins were quantified as 55% HgbS
and 45% Hgb C + A2. The solubility test was also positive. These
results are consistent with what disease process?
a. Hgb C trait
b. Sickle cell disease
c. Hgb SC disease
d. Hgb C disease -
correct answer ✅C
what is the basic hemoglobin defect in the thalassemias?
a. a structurally normal globin chain is absent or produced at lower
levels
b. iron is not incorporated into the protoporphyrin ring to form
heme
c. heme is producted at a lower concentration
d. one of the globin chains has an amino acid substitution -
correct answer ✅A
Iron overload in severe beta thalassemia (major) patients is
primarily a consequence of:
Questions & Answers (Grade A+)
The most common clinical application of flow cytometry is:
a. detection of fetomaternal hemorrhage
b. diagnosis of platelet disorders
c. differentiation of anemias
d. diagnosis of leukemias and lymphomas -
correct answer ✅D
Which of the following would be an unexpected finding in
homozygous beta0 thalassemia?
a. normal Hb F
b. bone marrow erythroid hyperplasia
c. target cells
d. severe anemia -
correct answer ✅A
a 13 yr old African American girl, was admitted to the hospital
appearing acutely ill with fever and abdominal pain. On physical
exam, an enlarged spleen was evident. Lab results were as follows:
Hgb 5 g/dL, Hct 15%, RBC 1.4 x 1012/L, WBC 2.2 x 109/L,
Reticulocyte count 1%, Segs 62%, bands 12%, lymphocytes 19%,
Monocytes 4%, Eosinophils 2%, basophils 1%, MCV 92%, MCHC
33%, Platelet count 400 x 109/L. Hemoglobin electrophoresis at
, MMSC433 Hematology 2 Exam 2
Questions & Answers (Grade A+)
alkaline pH showed one band in the HgbS position and one band in
the Hgb C position. The hemoglobins were quantified as 55% HgbS
and 45% Hgb C + A2. The solubility test was also positive. These
results are consistent with what disease process?
a. Hgb C trait
b. Sickle cell disease
c. Hgb SC disease
d. Hgb C disease -
correct answer ✅C
what is the basic hemoglobin defect in the thalassemias?
a. a structurally normal globin chain is absent or produced at lower
levels
b. iron is not incorporated into the protoporphyrin ring to form
heme
c. heme is producted at a lower concentration
d. one of the globin chains has an amino acid substitution -
correct answer ✅A
Iron overload in severe beta thalassemia (major) patients is
primarily a consequence of:
