Advanced Practice Nursing I | William
Paterson University
INTRODUCTION
This premium study bundle contains a collection of high-yield, board-style
practice questions designed for advanced practice nursing students
preparing for core clinical exams. Every entry features realistic clinical
case vignettes, lab interpretations, and immediate access to bolded
answers with comprehensive rationales. It serves as an essential, high-
converting test preparation resource optimized to help graduate students
master complex primary care diagnostics and pharmacological
interventions.
Question 1
An adult patient presents with a persistent, non-healing lesion on the right
upper cheek. On physical examination, you note a 0.6 cm, flesh-colored,
pearly nodule with prominent telangiectasias and a central ulceration with
rolled borders. Which of the following is the most likely diagnosis?
A) Malignant Melanoma
B) Squamous Cell Carcinoma
,C) Basal Cell Carcinoma
D) Actinic Keratosis
Answer: C) Basal Cell Carcinoma
Explanation: Basal cell carcinoma (BCC) characteristically presents
as a slow-growing, pearly or translucent nodule with telangiectasias
(visible small blood vessels) and rolled or raised borders, often
developing a central ulceration ("rodent ulcer") as it enlarges.
Squamous cell carcinoma typically appears more scaly,
hyperkeratotic, or crusted. Melanoma presents with asymmetry,
irregular borders, and variable pigmentation. Actinic keratosis is a
rough, scaly, precancerous lesion rather than a discrete nodule.
Question 2
According to the APRN Consensus Model, which of the following is
considered one of the four recognized APRN roles?
A) Clinical Nurse Leader (CNL)
B) Certified Registered Nurse Anesthetist (CRNA)
C) Nurse Administrator
D) Clinical Nurse Educator
Answer: B) Certified Registered Nurse Anesthetist (CRNA)
Explanation: The APRN Consensus Model explicitly defines and
recognizes exactly four distinct APRN roles: Certified Nurse
Practitioner (CNP), Certified Registered Nurse Anesthetist (CRNA),
Certified Nurse-Midwife (CNM), and Clinical Nurse Specialist (CNS).
,Roles such as Clinical Nurse Leader (CNL), administrators, and
nurse educators are graduate-prepared nursing roles, but they are
not categorized or licensed as APRN roles under this regulatory
framework.
Question 3
A 24-year-old male presents with acute localized erythema, warmth, and
swelling of the lower left extremity. The border of the erythema is diffuse
and poorly demarcated. There is no fluctuance, purulent drainage, or
abscess formation. He has no known drug allergies. Which of the following
is the first-line oral empirical antibiotic regimen?
A) Cephalexin (Keflex) 500 mg orally every 6 hours
B) Trimethoprim-sulfamethoxazole (Bactrim DS) 1 tablet orally twice daily
C) Clindamycin (Cleocin) 300 mg orally every 6 hours
D) Doxycycline 100 mg orally twice daily
Answer: A) Cephalexin (Keflex) 500 mg orally every 6 hours
Explanation: This patient presents with non-purulent cellulitis, which
is most commonly caused by beta-hemolytic streptococci (such as
Streptococcus pyogenes). For non-purulent cellulitis without
systemic signs or risk factors for MRSA, first-line empirical therapy
targets streptococci using an oral beta-lactam agent like
Cephalexin. Trimethoprim-sulfamethoxazole, Doxycycline, and
Clindamycin are utilized when purulent drainage or a suspected
abscess suggests Methicillin-Resistant Staphylococcus aureus
(MRSA).
, Question 4
A patient undergoes routine screening for tuberculosis using a Tuberculin
Skin Test (TST) with purified protein derivative (PPD). The patient has no
known medical comorbidities, is not immunosuppressed, has no history of
travel to endemic areas, and is not a healthcare worker or member of a
high-risk population. After 48 hours, the induration measures 12 mm. How
should the APRN interpret this result?
A) Positive, initiate immediate four-drug therapy
B) Positive, obtain a chest X-ray to rule out active disease
C) Negative, no further medical evaluation is indicated
D) Indeterminate, repeat the TST on the opposite arm
Answer: C) Negative, no further medical evaluation is indicated
Explanation: For individuals with no known risk factors for
tuberculosis, the diagnostic threshold for a positive TST induration
is 15 mm or greater. An induration of 12 mm is considered negative
in a low-risk individual. A 10 mm threshold applies to healthcare
workers, immigrants from high-prevalence countries, and injection
drug users. A 5 mm threshold applies to highly immunosuppressed
individuals (e.g., HIV-positive) or recent close contacts of individuals
with active TB.
Question 5
A 62-year-old patient with a 40 pack-year smoking history presents with
a chronic cough productive of white sputum for the past three years,
lasting at least three consecutive months each year. Physical examination