1
Chemotherapy
Chemotherapy Biotherapy
Certification Exam Questions
with Correct Verified Answers
Latest Update (2024/2025)
Guaranteed Pass
1. Lesson 4 A cautionary tale about routes - ANS ✔intrathecal
chemo- injects chemo directly into the subarachnoid space so it
reaches the CNA
-leukemia and lymphoma spreading to CNS since most chemo does not
cross blood brain barrier
2. intrathecal chemo - ANS ✔ONLY methotrexate and cytarabine can
be given IT
-IT hydrocorisone given at same time to reduce inflammation
3. vincristine - ANS ✔dilute in 20mL minibag and infuse over short
time- IVP not reommended
vinblastine -dilute in 25-50 ns
4. Lesson 5 Antitumor Antibiotics - ANS ✔-anthracyclines: interfere
with enzymes for DNA to replicate, work phases of the cell cycle
lifetime dose limites because they are cardiotoxic
-daunorubicin, doxorubicin, epirubicin, idarubicin
Chemotherapy Biotherapy Certification
, 2
Chemotherapy
nonanthracycline: actinomycin, mitomycin, bleomycin
5. doxorubicin - ANS ✔vesicant
extravasation possible- must eval cardiac funciton, ongoing cardiac
monitoring, hypersensitivity risk
-nausea/ vomiting, mucositis, diarrhea, myelosupression, hepatic
impairment, secondary cancer
-cardiac: SOB< skipped beats, weight gain
-myelosuppress: oral temp daily, report >100.5
GI: nausea vomiting diarrhea, inspect mucosa
neuro: numbness/ tingling, burning
GU: change in color of urine
6. dexrazoxane - ANS ✔cardiac protectant given before
7. bleomycin - ANS ✔antitumor antibiotic - lifetime dose warning
-can cause hypersensitivity, skin reaction
-report SOB< skin issues, protect from sun
8. Lesson 6 symptoms that can be dose limiting - ANS ✔chemo
induced nausea and vomiting
-lead to dehydration, dec functional status, increased costs and withdrawal
from treatment
-70% patient will experience.
Chemotherapy Biotherapy Certification
, 3
Chemotherapy
RISK Factors: younger, history of low alcohol consumption, female,
morning/ motion sickness
HEC: highly emetogenic - carmustine, cisplatin, cyclophosphamide,
daarbazine, mechlorethamine, streptozocin
9. CINV - ANS ✔chemo infuced nausea vomiting- vomiting center is
central area responsible for CINV
-patient are at risk for 2-3 days after last dose of cheom
10. Antiemetics - ANS ✔serotonin antagonists
-dolasetron, granisetron, ondansetron, palonosetron
neurokinin antagonists- aprepitant, fosaprepitant
steroids: dexamethasone
11. Cutaneous Side effects of chemo - ANS ✔5FU and
capecitabine has been noted to cause the worst skin resactions
-hand foot syndrome
-palmar plantar erythrodysesthesia - painful- flaking swelling blisters and
sores
avoid hot water, impacton feet and rubbing
12. myelosuppression - ANS ✔suppression of bone marroe, red
blood and platelets
NADIR: point at which blood cell counts are at the lowest after treatemtn.
usually 7-1 days after cyce
Chemotherapy Biotherapy Certification
Chemotherapy
Chemotherapy Biotherapy
Certification Exam Questions
with Correct Verified Answers
Latest Update (2024/2025)
Guaranteed Pass
1. Lesson 4 A cautionary tale about routes - ANS ✔intrathecal
chemo- injects chemo directly into the subarachnoid space so it
reaches the CNA
-leukemia and lymphoma spreading to CNS since most chemo does not
cross blood brain barrier
2. intrathecal chemo - ANS ✔ONLY methotrexate and cytarabine can
be given IT
-IT hydrocorisone given at same time to reduce inflammation
3. vincristine - ANS ✔dilute in 20mL minibag and infuse over short
time- IVP not reommended
vinblastine -dilute in 25-50 ns
4. Lesson 5 Antitumor Antibiotics - ANS ✔-anthracyclines: interfere
with enzymes for DNA to replicate, work phases of the cell cycle
lifetime dose limites because they are cardiotoxic
-daunorubicin, doxorubicin, epirubicin, idarubicin
Chemotherapy Biotherapy Certification
, 2
Chemotherapy
nonanthracycline: actinomycin, mitomycin, bleomycin
5. doxorubicin - ANS ✔vesicant
extravasation possible- must eval cardiac funciton, ongoing cardiac
monitoring, hypersensitivity risk
-nausea/ vomiting, mucositis, diarrhea, myelosupression, hepatic
impairment, secondary cancer
-cardiac: SOB< skipped beats, weight gain
-myelosuppress: oral temp daily, report >100.5
GI: nausea vomiting diarrhea, inspect mucosa
neuro: numbness/ tingling, burning
GU: change in color of urine
6. dexrazoxane - ANS ✔cardiac protectant given before
7. bleomycin - ANS ✔antitumor antibiotic - lifetime dose warning
-can cause hypersensitivity, skin reaction
-report SOB< skin issues, protect from sun
8. Lesson 6 symptoms that can be dose limiting - ANS ✔chemo
induced nausea and vomiting
-lead to dehydration, dec functional status, increased costs and withdrawal
from treatment
-70% patient will experience.
Chemotherapy Biotherapy Certification
, 3
Chemotherapy
RISK Factors: younger, history of low alcohol consumption, female,
morning/ motion sickness
HEC: highly emetogenic - carmustine, cisplatin, cyclophosphamide,
daarbazine, mechlorethamine, streptozocin
9. CINV - ANS ✔chemo infuced nausea vomiting- vomiting center is
central area responsible for CINV
-patient are at risk for 2-3 days after last dose of cheom
10. Antiemetics - ANS ✔serotonin antagonists
-dolasetron, granisetron, ondansetron, palonosetron
neurokinin antagonists- aprepitant, fosaprepitant
steroids: dexamethasone
11. Cutaneous Side effects of chemo - ANS ✔5FU and
capecitabine has been noted to cause the worst skin resactions
-hand foot syndrome
-palmar plantar erythrodysesthesia - painful- flaking swelling blisters and
sores
avoid hot water, impacton feet and rubbing
12. myelosuppression - ANS ✔suppression of bone marroe, red
blood and platelets
NADIR: point at which blood cell counts are at the lowest after treatemtn.
usually 7-1 days after cyce
Chemotherapy Biotherapy Certification
