ALU 301 ACTUAL TEST PAPER QUESTIONS AND
ANSWERS SET A+
✔✔Discuss the common uses of immunotherapy. - ✔✔Cancer-metastatic melanoma-
Interferon alpha, methotrexate
Allergies
Rheumatoid Arthritis-Methotrexate, Remicade, Enbrel, Humira, Anakinra
Psoriasis & Crohn's-Kineret, toclizumab, Acetema, Rituximab,
Rituxan
Graves
Hashimoto's
Lupus/SLE
Glomerulonephritis
X-linked lymphopholiferative syndrome
DiGeorge syndrome
Agammaglobulinemia
X-linked agammaglobulinemia
IGA defficiency
CVID
SCID
Polyarthritis
Juvenile RA
Dermatomyositis
Graves
✔✔What clinical features can differentiate ulcerative colitis from Crohn's disease? -
✔✔UC-only colon, only mucosa (not whole wall), begins in rectum, continuous, most
common symptom is rectal bleeding
Crohn's-inflammation all layers of wall, lymph nodes, mouth to anus, most common
symptom abdominal pain, skip lesions
, ✔✔Under what conditions can surgical therapy be curative for inflammatory bowel
disease? - ✔✔UC-long standing, severe refractory to med tx, presence dysplasia or
cancer on surveillance bx.
✔✔Ulcerative Colitis - ✔✔more common in males, rectal bleeding is common,
abdominal pain uncommon, no fistula, stricture only with malignancy, perianal abscess
uncommon, depth of involvement mucosa and submucosa, small bowel not involved
✔✔Crohn's Disease - ✔✔more common in females, occassional rectal bleeding,
abdominal pain common, fistula common, stricture common, perianal abscesses
common, type of involvement discontinuous skip lesions, depth transmural, small bowel
involved
✔✔What are commonly seen signs and symptoms of active rheumatoid arthritis on a
physician's examination? - ✔✔duration of morning stiffness, presence and number of
inflamed joijnts and any changes in previously affected joints, signs of active synovitis,
including, swelling or effusion the joint is often described as feeling spongy or doughy,
mechanical changes such as loss of motion, crepitus, instability, malalignment,
deformity, or decrease in grip, pain and tenderness, particulary with movement or when
pressure is applied, prsesence of heat or redness joints may be warm, but they are not
usually hot, presence of rheumatoid nodules, systemic manifestations
✔✔Describe the systemic manifestations of rheumatoid arthritis. - ✔✔vasculitis, skin,
skeletal, muscle, eye involvement, lung disease, cardiovascular, neurological, kidney,
hematological manifestations
✔✔Discuss the laboratory tests that are potentially useful for diagnosing rheumatoid
arthritis (RA) and monitoring disease activity - ✔✔Rheumatoid Factor (RF), Serum anti-
cyclic citrullinated peptide antibodies (anti-CCP), anti-MCV antibodies, acute phase
reactants, complete blood count
✔✔Describe the similarities between juvenile rheumatoid arthritis (JRA)and adult
rheumatoid arthritis (RA). - ✔✔Treatment of JRA is similar to adult RA with use of
NSAIDS for mild disease and DMARDs when progressive joint involvement is observed.
✔✔List the possible contributing factors to the incidence of cardiovascular disease in
the setting of rheumatoid arthritis (RA). - ✔✔Decreased mobility and sedentary lifestyle
✔✔Name the three possible outcomes of an infection. - ✔✔The infection overwhelms
the individual and death results, the immune system, with or without help of treatment,
eradicates teh infection, the infectious agent reaches a state of equilibrium with the
host, and a chronic or latent infection results
ANSWERS SET A+
✔✔Discuss the common uses of immunotherapy. - ✔✔Cancer-metastatic melanoma-
Interferon alpha, methotrexate
Allergies
Rheumatoid Arthritis-Methotrexate, Remicade, Enbrel, Humira, Anakinra
Psoriasis & Crohn's-Kineret, toclizumab, Acetema, Rituximab,
Rituxan
Graves
Hashimoto's
Lupus/SLE
Glomerulonephritis
X-linked lymphopholiferative syndrome
DiGeorge syndrome
Agammaglobulinemia
X-linked agammaglobulinemia
IGA defficiency
CVID
SCID
Polyarthritis
Juvenile RA
Dermatomyositis
Graves
✔✔What clinical features can differentiate ulcerative colitis from Crohn's disease? -
✔✔UC-only colon, only mucosa (not whole wall), begins in rectum, continuous, most
common symptom is rectal bleeding
Crohn's-inflammation all layers of wall, lymph nodes, mouth to anus, most common
symptom abdominal pain, skip lesions
, ✔✔Under what conditions can surgical therapy be curative for inflammatory bowel
disease? - ✔✔UC-long standing, severe refractory to med tx, presence dysplasia or
cancer on surveillance bx.
✔✔Ulcerative Colitis - ✔✔more common in males, rectal bleeding is common,
abdominal pain uncommon, no fistula, stricture only with malignancy, perianal abscess
uncommon, depth of involvement mucosa and submucosa, small bowel not involved
✔✔Crohn's Disease - ✔✔more common in females, occassional rectal bleeding,
abdominal pain common, fistula common, stricture common, perianal abscesses
common, type of involvement discontinuous skip lesions, depth transmural, small bowel
involved
✔✔What are commonly seen signs and symptoms of active rheumatoid arthritis on a
physician's examination? - ✔✔duration of morning stiffness, presence and number of
inflamed joijnts and any changes in previously affected joints, signs of active synovitis,
including, swelling or effusion the joint is often described as feeling spongy or doughy,
mechanical changes such as loss of motion, crepitus, instability, malalignment,
deformity, or decrease in grip, pain and tenderness, particulary with movement or when
pressure is applied, prsesence of heat or redness joints may be warm, but they are not
usually hot, presence of rheumatoid nodules, systemic manifestations
✔✔Describe the systemic manifestations of rheumatoid arthritis. - ✔✔vasculitis, skin,
skeletal, muscle, eye involvement, lung disease, cardiovascular, neurological, kidney,
hematological manifestations
✔✔Discuss the laboratory tests that are potentially useful for diagnosing rheumatoid
arthritis (RA) and monitoring disease activity - ✔✔Rheumatoid Factor (RF), Serum anti-
cyclic citrullinated peptide antibodies (anti-CCP), anti-MCV antibodies, acute phase
reactants, complete blood count
✔✔Describe the similarities between juvenile rheumatoid arthritis (JRA)and adult
rheumatoid arthritis (RA). - ✔✔Treatment of JRA is similar to adult RA with use of
NSAIDS for mild disease and DMARDs when progressive joint involvement is observed.
✔✔List the possible contributing factors to the incidence of cardiovascular disease in
the setting of rheumatoid arthritis (RA). - ✔✔Decreased mobility and sedentary lifestyle
✔✔Name the three possible outcomes of an infection. - ✔✔The infection overwhelms
the individual and death results, the immune system, with or without help of treatment,
eradicates teh infection, the infectious agent reaches a state of equilibrium with the
host, and a chronic or latent infection results
