goal of the coagulation cascade?
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to make fibrin
components of the atheroma CAP
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collagen
smooth muscle
causes of local edema
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1. inflammation
2. type 1 hypersensitivity
3. occlusive venous thrombosis
4. obstruction of lymphatic system
platelets have a receptor on their membrane called GpII/IIIa. fibrinogen binds to
these receptors and causes platelets to aggregate (forms fibrinogen bridges).
this finishes the platelet plug ("loose thrombus")
Give this one a try later!
Platelet aggregation
Air bubbles enter the bloodstream from injection, punctured lung, or open vessel.
when these travel to the heart, they mix with blood making a frothy mass. this mass
can block blood flow
Give this one a try later!
air emboli
deficiency in the amount of oxygen reaching the tissues (decreased concentration of
O2 in the blood)
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Hypoxia
* ischemia is usually a cause, but you can get hypoxia without ischemia, ex.
carbon monoxide poisoning (lowers the oxygen carrying capacity, since
CO binds to hemoglobin instead of O2)
the common belief that Atherosclerosis is caused by endothelial damage/injury, and
fat is able to enter the intima and form plaques
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response to injury hypothesis
lack of blood supply to a tissue
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ishemia
chest pain that is specifically caused by ischemia (decreased blood flow to the heart)
Give this one a try later!
Angina
Give this one a try later!
to make fibrin
components of the atheroma CAP
Give this one a try later!
collagen
smooth muscle
causes of local edema
,Give this one a try later!
1. inflammation
2. type 1 hypersensitivity
3. occlusive venous thrombosis
4. obstruction of lymphatic system
platelets have a receptor on their membrane called GpII/IIIa. fibrinogen binds to
these receptors and causes platelets to aggregate (forms fibrinogen bridges).
this finishes the platelet plug ("loose thrombus")
Give this one a try later!
Platelet aggregation
Air bubbles enter the bloodstream from injection, punctured lung, or open vessel.
when these travel to the heart, they mix with blood making a frothy mass. this mass
can block blood flow
Give this one a try later!
air emboli
deficiency in the amount of oxygen reaching the tissues (decreased concentration of
O2 in the blood)
, Give this one a try later!
Hypoxia
* ischemia is usually a cause, but you can get hypoxia without ischemia, ex.
carbon monoxide poisoning (lowers the oxygen carrying capacity, since
CO binds to hemoglobin instead of O2)
the common belief that Atherosclerosis is caused by endothelial damage/injury, and
fat is able to enter the intima and form plaques
Give this one a try later!
response to injury hypothesis
lack of blood supply to a tissue
Give this one a try later!
ishemia
chest pain that is specifically caused by ischemia (decreased blood flow to the heart)
Give this one a try later!
Angina