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Exam (elaborations)

ATI Pharmacology Practice Exam (2026) – Graded A Questions and Answers Review

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This document contains practice exam questions and answers for the ATI Pharmacology Exam (2026), designed to reflect high-quality, graded A-level performance. It covers key topics such as drug classifications, mechanisms of action, adverse effects, dosage calculations, medication administration, and patient education. The material is structured to reinforce essential pharmacological knowledge, enhance clinical reasoning, and support effective exam preparation.

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ATI Pharmacology Practice Exam Graded
A 2026
A nurse is providing discharge instructions to a client who has heart failure and a new
prescription for captopril. Which of the following client statements indicates an
understanding of the teaching?

a. "I should take this medication with food."
b. "I should take naproxen if I develop joint pain."
c. "I should tell my provider if I develop a sore throat."
d. "I should expect the medication to cause my urine to look orange." - c. "I should tell
my provider if I develop a sore throat."

The client should report a sore throat to the provider because this can indicate
neutropenia, a serious adverse effect of captopril. Neutropenia can be reversed if it is
identified early and the medication is promptly discontinued.

A nurse is providing teaching to a client who has peptic ulcer disease and is to start a
new prescription for sucralfate. Which of the following actions of sucralfate should the
nurse include in the teaching?

a. Decreases stomach acid and secretion
b. Neutralizes acid in the stomach
c. Forms a protective barrier
d. Treats ulcers by eradicating H. pylori - C. For a a protective barrier over ulcers

Secretions by the parietal chief cells, hydrochloric acid and pepsin, can further irritate
the ulcerated areas. Sucralfate, a mucosal protectant, forms a gel-like substance that
coats the ulcer, creating a barrier to hydrochloric acid and pepsin.

A nurse is providing teaching to a client who has multiple sclerosis and a new
prescription for methylprednisolone. Which of the following instructions should the nurse
include? (SATA)

a. Blood glucose levels will be monitored during therapy
b. Avoid contact with people who have known infections
c. Take the medication 1 hr before breakfast
d. Decrease dietary intake of foods containing potassium
e. Grapefruit juice can increase the effects of the medication - a. Blood glucose levels
will be monitored during therapy

,b. mAvoid mcontact mwith mpeople mwho mhave mknown minfections m
e. mGrapefruit mjuice mcan mincrease mthe meffects mof mthe mmedication m
m

a. The mnurse mshould mmonitor mthe mclient mfor mhyperglycemia mwhile mproviding
mmethylprednisolone mto mthe mclient. mGlucocorticoids, msuch mas mmethylprednisolone,

mincrease mserum mglucose mlevels mand mcan mrequire mmanagement mwith minsulin mor

mantihyperglycemia. m

b. The mnurse mshould minstruct mthe mclient mto mavoid mexposures mto minfectious magents,
msuch mas mcontact mwith mthose mwho mhave mactive minfections mor millnesses.

mGlucocorticoids, mwhich mas mmethylprednisolone, mdepress mthe mimmune msystem, mplacing

mthe mclient mat man mincreased mrisk mfor mdeveloping man minfection. m

e. mThe mnurse mshould min mstrict mthe mclient mthat mgrapefruit mand mgrapefruit mjuice mcan
mincrease mthe mlevel mof mmethylprednisolone min mthe mbody. m
m

The mnurse mis mproviding mdischarge mteaching mabout mhandling mmedication mto ma mclient
mwho mis m
m
to mcontinue mtaking moral mtransmucosal mfentanyl mraspberry-flavored mlozenges mon ma
mstick.
m
Which mof mthe mfollowing minformation mshould mthe mnurse minclude min mthe
mteaching?
m

a. Chew mon mthe mmedication mstick mto mrelease mthe mmedication m
b. Leave mthe mmedication mstick min mone mlocation mof mthe mmouth muntil mmelted m
c. Allow mthe mmedication m1 mhr mfor mthe manalgesia meffects mto mbegin m
d. Store munused mmedication msticks min ma mstorage mcontainer m- md. mStore munused
mmedication msticks min ma mstorage mcontainer m
m

The mnurse mshould minstruct mthe mclient mto mstore munused, mor mpartially mused, mmedications
msticks m
m
in mthe msafe mstorage mcontainer mthat mcomes min mthe mkit mwhen mthe mmedication mis
minitially
m
prescribed.
m

A mnurse mis mreviewing mthe mECG mof ma mclient mwho mis mreceiving mIV mfurosemide mfor mheart
mfailure. m
m
The mnurse mshould midentify mwhich mof mthe mfollowing mfindings mas man
mindication mof
m
hypokalemia?
m

a. Tall, mtented mT mwaves m
b. Presence mof mU mwaves m
c. Widened mQRS mcomplex m
d. ST melevation m- mb. mPresence mof mU mwaves m
m

A mnurse mis mcaring mfor ma mclient mand mis mtaking moral mmorphine mand mdocusate msodium.
mThe mnurse mshould minstruct mthe mclient mthat mtaking mthe mdocusate msodium mdaily mcan

mminimize mwhich mof mthe mfollowing madverse meffects mof mmorphine? m

, m

a. Constipation m
b. Drowsiness m
c. Facial mflushing m
d. Itching m- ma. mConstipation m
m

Constipation mis ma mcommon madverse meffect mof mmorphine mthat mcan mbe mminimized mby
mtaking m
m
docusate msodium, ma mstool msoftener mthat mpromotes measier mevacuation mof
mstool mby
m
increasing mwater mand mfat min mthe
mintestine.
m

A mnurse mis mplanning mcare mfor ma mclient mwho mis mreceiving mmannitol mvia mcontinuous mIV
minfusion. m
m
The mnurse mshould mmonitor mfor mwhich mof mthe mfollowing madverse
meffects?
m
m
a. mWeight

mloss
m
b. mIncreased mintraocular

mpressure
m
c. mAuditory

mhallucinations


d. mBibasilar mcrackles m- md. mBibasilar
mcrackles
m

Mannitol, man mosmotic mdiuretic, mcan mprecipitate mheart mfailure mand mpulmonary
medema, m


therefore, mthe mnurse mshould mrecognize mlung mcrackles mas man mindication mof ma
mpotential m
m
complication mand mstop mthe
minfusion.
m

A mnurse mis mproviding mteaching mto ma mclient mwho mhas ma mgastric mulcer mand ma mnew
mprescription m
m
for mranitidine. mWhich mof mthe mfollowing minstructions mshould mthe mnurse
minclude?
m
m
a. m"Take mthe mmedication mon man mempty mstomach mfor mfull
meffectiveness."


b. m" mYou mmay mdiscontinue mthis mmedication mwhen mstomach mdiscomfort
msubsides."
m
c. m"Report myellowing mof mthe
mskin."

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August 5, 2026
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