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ATI Pharmacology Exam (2026) – Comprehensive Questions and Answers Review

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This document contains questions and answers for the ATI Pharmacology Exam (2026), focusing on essential pharmacological concepts and nursing applications. It covers key topics such as drug classifications, mechanisms of action, adverse effects, dosage calculations, medication administration, and patient education. The material is structured to reinforce core knowledge, enhance clinical reasoning, and support effective exam preparation.

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lOMoARcPSD|285 053 80
lOMoARcPSD|285 053 80




ATI Pharmacology 2026 Exam
1) A nurse is caring for a pt who is receiving Haloperidol. The nurse should identify which of the following findings as an adverse effect of the med?

-Akathisia = CORRECT ANSWER
An adverse effect associated with haloperidol is the development of extrapyramidal manifestations such as dystonia, pseudoparkinsonism, and akathisia.

-Paresthesia
Haloperidol, an antipsychotic neuroleptic medication, can cause CNS adverse effects such as seizures, confusion, and neuroleptic syndrome. However,
paresthesia is not an adverse effect of haloperidol.

-Excess tear production
Haloperidol has anticholinergic properties that can cause sensory adverse effects such as increased intraocular pressure, blurred vision, and dry eyes.

-Anxiety
Haloperidol can be prescribed to treat severe agitation as well as psychotic manifestations.
2) A nurse is providing teaching to a pt who is to start taking Sumatriptan. Which of the following adverse effects should the nurse instruct the pt to monitor for and
report to the provider?

-Chest pressure= CORRECT ANSWER
Sumatriptan is an antimigraine agent which can cause coronary vasospasms, resulting in angina. The client should report chest pressure or heavy arms to
the provider.

-White patches on the tongue
White patches on the tongue can indicate a fungal infection, which is not an adverse effect of sumatriptan.

-Bruising
Ecchymosis can indicate thrombocytopenia, which is not an adverse effect of sumatriptan.

-Insomnia
Sumatriptan can cause drowsiness and sedation as an adverse effect of the medication.

3) A nurse is teaching a pt who is starting to take Amitriptyline. Which of the following findings should the nurse include in the teaching as an adverse effect of the
med?

-Diarrhea
Constipation is an adverse effect of amitriptyline.

-Cough
Developing a cough is not an adverse effect of amitriptyline.

-Urinary retention = CORRECT ANSWER
The nurse should instruct the client that amitriptyline causes the anticholinergic effect of urinary retention.

-Increased libido
A decrease in libido is an adverse effect of amitriptyline.
4) A nurse is assessing a pt who is taking Tamoxifen to treat breast cancer. Which of the following findings is the priority for the nurse to report to the provider?

-Hot flashes
The client is at risk for hot flashes as an adverse effect of tamoxifen; however, another finding is the priority to report to the provider. The nurse should
encourage the client to avoid caffeine and spicy foods to prevent hot flashes.

-Gastrointestinal irritation
The client is at risk for gastrointestinal irritation (GI) as an adverse effect of tamoxifen; however, another finding is the priority to report to the provider. The
nurse should administer the medication with food or fluids to reduce GI irritation.

-Vaginal dryness
The client is at risk for vaginal dryness as an adverse effect of tamoxifen; however, another finding is the priority to report to the provider. The nurse should
encourage the client to use vaginal moisturizers if dryness occurs.

, lOMoARcPSD|285 053 80




-Leg mtenderness m= mCORRECT mANSWER m
The mgreatest mrisk mto mthis mclient mis mthe mdevelopment mof ma mthromboembolism, mwhich mis man madverse meffect mof mtamoxifen. mThe mnurse mshould
malso mmonitor mthe mclient mfor mother mmanifestations mof ma mthromboembolism, mincluding mleg mtenderness, mredness, mswelling, mand mshortness mof

mbreath. m
m
m
5) mA mnurse mis mteaching ma mpt mwho mis mtaking mAllopurinol mfor mthe mtreatment mof mgout. mWhich mof mthe mfollowing minfo mshould mthe mnurse minclude min mthe
mteaching? m
m
-Plan mto mincrease mthe mdosage meach mweek mby m200 mmg mincrements. m
The mnurse mshould minstruct mthe mclient mto mincrease mthe mdosage meach mweek mby m50 mto m100 mmg muntil mthey mexperience mrelief mor mreach ma
mmaximum mof m800 mmg mdaily. m
m
-Prolonged muse mof mthe mmedication mcan mcause mglaucoma. m

, lOMoARcPSD|285 053 80




The mnurse mshould minstruct mthe mclient mthat mthe m prolonged muse mof mallopurinol mcan mcause mcataracts; mtherefore, mthe mclient mshould mhave m periodic
mophthalmic mcheckups. m
m
-Drink m2 mL mof mwater mdaily. m= mCORRECT mANSWER m
The mnurse mshould minstruct mthe mclient mto mdrink mat mleast m2 mL mof mwater meach mday mto mprevent mrenal mstone mformation mand mkidney minjury,
mbecause mallopurinol mis meliminated mthrough mthe mkidneys. m
m
-A mfine mred mrash mis mtransient mand mcan mbe mtreated mwith mantihistamines. m
The m nurse mshould minstruct mthe mclient mto mreport ma mrash mto mthe m provider mimmediately mas mthis mcan mbe man mindication mof mhypersensitivity
msyndrome, ma mlife-threatening mtoxicity. mTreatment mfor mallopurinol mtoxicity mcan mrequire mhemodialysis mor mthe madministration m of mglucocorticoid
mmedications m
m

6) mA mnurse mis mcaring mfor ma mpt mwho mhas mdiabetes m mellitus mand mis mtaking mGlyburide. mThe mpt mreports mfeeling mconfused mand manxious. mWhich m of mthe
mfollowing mactions mshould mthe mnurse mtake mfirst? m
m
-Perform ma mcapillary mblood mglucose mtest. m= mCORRECT mANSWER m
The mgreatest mrisk mto mthis mclient mis minjury mfrom mhypoglycemia. mTherefore, mthe mnurse mshould mperform ma mcapillary mblood mglucose mtest mto
mdetermine mthe mclient's mblood mglucose mstatus. mManifestations mof mhypoglycemia minclude mweakness, manxiety, mconfusion, msweating, mand mseizures.
m
m
-Provide mthe mclient mwith ma mprotein-rich msnack. m
The mnurse mshould mprovide mthe mclient mwith ma mprotein-rich msnack mafter mdetermining mthe mclient's mblood mglucose mvalue mand mproviding ma
mcarbohydrate mfirst. mHowever, mthere mis manother maction mthat mthe mnurse mshould mtake mfirst. m
m
-Give mthe mclient m120 mmL m(4 moz) mof morange mjuice. m
The mnurse mshould mgive mthe mclient m10 mto m15 mg mof mcarbohydrates, msuch mas m4 moz mof morange mjuice, mto mtreat mhypoglycemia. mHowever, mthere mis
manother maction mthat mthe mnurse mshould mtake mfirst. m
m
-Schedule man mearly mmeal mtray. m
The mnurse mshould mschedule man mearly mmeal mtray mto mmaintain mthe mclient's mblood mglucose mlevel mfollowing mthe minitial minterventions mfor
mhypoglycemia. mHowever, mthere mis manother maction mthe mnurse mshould mtake mfirst. m
m
7) mA mnurse mis madministering mCefotetan mvia mintermittent mIV mbolus mto ma mpt mwho msuddenly mdevelops mdyspnea mand mwidespread mhives. mWhich mof mthe
mfollowing mactions mshould mthe mnurse mtake mfirst? m
m
-Administer mepinephrine m0.5 mmL mvia mIV mbolus. m
The mnurse mshould madminister mepinephrine, mwhich mis ma mbeta-adrenergic magonist mthat mcan mstimulate mthe mheart, mcause mvasoconstriction mof mblood
mvessels min mthe mskin mand mmucous mmembranes, mand mcause mbronchodilation min mthe mlungs. mHowever, mthere mis manother maction mthe mnurse mshould
mtake mfirst. m
m
-Discontinue mthe mmedication mIV minfusion. m= mCORRECT mANSWER m
The mgreatest mrisk mto mthe mclient mis mrespiratory marrest mfrom manaphylaxis. mTherefore, mthe mfirst maction mthe mnurse mshould mtake mis mto mdiscontinue
mthe mmedication mIV minfusion mto mprevent mthe mclient mfrom mreceiving mmore m medication. mHowever, mthe m nurse mshould mnot mremove mthe mIV
mcatheter. mInstead, mthe mnurse mshould mchange mthe mtubing mand madminister m0.9% msodium mchloride mby mcontinuous mIV minfusion. m
m
-Elevate mthe mclient's mlegs mabove mthe mlevel mof mthe mheart. m
The mnurse mshould melevate mthe mclient's mlegs mand mfeet mto ma mlevel mabove mthe mclient's mheart mto mfacilitate mblood mflow mto mthe mvital morgans.
mHowever, mthere mis manother maction mthe mnurse mshould mtake mfirst. m
m
-Collect ma mblood mspecimen mfor mABGs. m
The mnurse mshould mcollect ma mblood mspecimen mfor mABGs mlevels mto mevaluate mthe mclient's mrespiratory mstatus. mHowever, mthere mis manother maction
mthe mnurse mshould mtake mfirst. m

8) A mnurse mis mpreparing mto madminister m0.9% mSodium mChloride m1000mL mIV mover m8hr mto ma mpt. mThe mdrop mfactor mof mthe mmanual mIV mtubing mis
m15gtt/mL. mThe mnurse mshould mset mthe mmanual mIV minfusion mto mdeliver mhow mmany m mgtt/min? m(round mto mnearest mwhole m#, mdo mnot muse mtrailing mzero) m
m
The mnurse mshould mset mthe mmanual mIV minfusion mto mdeliver m0.9% msodium mchloride mIV mat m31 mgtt/min. m= mCORRECT mANSWER m
m

9) A mnurse mis mteaching mabout ma mnew mprescription mfor mCiprofloxan mto m a mpt mwho mhas ma mUTI. mThe mnurse mshould midentify mwhich mof mthe m following
mstatements mas man mindication mthat mthe mpt munderstands mthe mteaching? m
m
-"I mwill mtake mthis mmedication mwith man mantacid mto mprevent mgastrointestinal mupset." m
The mclient mshould mavoid mtaking mciprofloxacin mwith man mantacid mcontaining maluminum, mmagnesium, mor mcalcium mbecause mthis mcan mdecrease mthe
meffectiveness mof mthe mmedication. mThe mnurse mshould minstruct mthe mclient mto mtake mantacids m2 mhr mbefore mor m6 mhr mafter mthe mciprofloxacin. m
m
-"I mwill mstop mtaking mthis mmedication mwhen mI mno mlonger mhave mpain mupon murination." m
The mclient mshould mtake mthe mfull mcourse mof mciprofloxacin mto mprevent mreoccurring mcolonization mof mbacteria. m
m
-"I mwill mreport many msigns mof mtendon mpain mor mswelling." m= mCORRECT mANSWER m
Ciprofloxacin, ma mfluoroquinolone, mis massociated mwith ma mrisk mof mtendon mrupture. mThis mrisk mis mincreased min molder madult mclients, mso mthe m client
mshould mnotify mthe mprovider mat mthe monset mof mtendon mpain mor mswelling. m
m
-"I mwill mtake mthis mmedication mwith mmilk." m
The mclient mshould mtake mciprofloxacin mwith mwater mand mincrease mfluids mto m2 mto m3 mL mdaily mto mavoid mthe mdevelopment mof mcrystals min mthe
mkidneys. mMilk mproducts mwill mdecrease mthe mabsorption mof mthe mmedication. m

10) mA mnurse mis mpreparing mto mteach ma mpt mwho mis mto mstart ma mnew mprescription mfor mextended mrelease mVerapamil. mWhich mof mthe mfollowing minstructions
mshould mthe mnurse mplan mto minclude? m
m
-Take mthe mmedication mon man mempty mstomach. m

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