ATI Pharmacology Proctored Examination
2026–2027 | Comprehensive Question
Practice Test with Answers & Rationales|
Free Pdf Access
1. A nurse is preparing to administer digoxin to a client. Which assessment
should be performed first?
A. Respiratory rate
B. Apical pulse
C. Temperature
D. Oxygen saturation
Correct Answer: B
Rationale: Digoxin can cause bradycardia. The nurse should assess the apical pulse and
withhold the medication if the pulse is below prescribed parameters.
2. A client receiving morphine develops a respiratory rate of 8/min. Which
medication should the nurse administer?
A. Flumazenil
B. Protamine sulfate
C. Naloxone
D. Vitamin K
Correct Answer: C
Rationale: Naloxone is an opioid antagonist used to reverse respiratory depression caused
by opioids.
3. A client receiving heparin develops excessive bleeding. Which antidote
should the nurse anticipate administering?
,A. Vitamin K
B. Protamine sulfate
C. Acetylcysteine
D. Naloxone
Correct Answer: B
Rationale: Protamine sulfate reverses the anticoagulant effects of heparin.
4. Which laboratory test is used to monitor warfarin therapy?
A. aPTT
B. INR
C. Troponin
D. Potassium
Correct Answer: B
Rationale: INR is the primary laboratory value used to monitor warfarin effectiveness and
safety.
5. A nurse is administering insulin lispro. When should the medication be
given?
A. 1 hour before meals
B. At bedtime
C. Within 15 minutes of meals
D. 2 hours after meals
Correct Answer: C
Rationale: Insulin lispro is rapid-acting and should be administered immediately before
meals.
6. Which finding suggests digoxin toxicity?
A. Nausea and blurred vision
B. Increased appetite
C. Hypertension
D. Weight gain
Correct Answer: A
Rationale: Gastrointestinal symptoms and visual disturbances are common signs of
digoxin toxicity.
, 7. A client taking furosemide should be monitored for:
A. Hyperkalemia
B. Hypokalemia
C. Hypercalcemia
D. Hypermagnesemia
Correct Answer: B
Rationale: Furosemide is a loop diuretic that increases potassium excretion.
8. Which medication is commonly prescribed for acute angina?
A. Nitroglycerin
B. Digoxin
C. Warfarin
D. Furosemide
Correct Answer: A
Rationale: Nitroglycerin causes vasodilation and relieves myocardial ischemia.
9. A client taking nitroglycerin reports dizziness. The nurse recognizes this as:
A. An expected effect of vasodilation
B. Evidence of toxicity
C. Hyperglycemia
D. Infection
Correct Answer: A
Rationale: Vasodilation may lead to orthostatic hypotension and dizziness.
10. Which medication classification does albuterol belong to?
A. Beta2-adrenergic agonist
B. ACE inhibitor
C. Anticoagulant
D. Opioid analgesic
Correct Answer: A
Rationale: Albuterol is a short-acting beta2 agonist used for bronchodilation.
2026–2027 | Comprehensive Question
Practice Test with Answers & Rationales|
Free Pdf Access
1. A nurse is preparing to administer digoxin to a client. Which assessment
should be performed first?
A. Respiratory rate
B. Apical pulse
C. Temperature
D. Oxygen saturation
Correct Answer: B
Rationale: Digoxin can cause bradycardia. The nurse should assess the apical pulse and
withhold the medication if the pulse is below prescribed parameters.
2. A client receiving morphine develops a respiratory rate of 8/min. Which
medication should the nurse administer?
A. Flumazenil
B. Protamine sulfate
C. Naloxone
D. Vitamin K
Correct Answer: C
Rationale: Naloxone is an opioid antagonist used to reverse respiratory depression caused
by opioids.
3. A client receiving heparin develops excessive bleeding. Which antidote
should the nurse anticipate administering?
,A. Vitamin K
B. Protamine sulfate
C. Acetylcysteine
D. Naloxone
Correct Answer: B
Rationale: Protamine sulfate reverses the anticoagulant effects of heparin.
4. Which laboratory test is used to monitor warfarin therapy?
A. aPTT
B. INR
C. Troponin
D. Potassium
Correct Answer: B
Rationale: INR is the primary laboratory value used to monitor warfarin effectiveness and
safety.
5. A nurse is administering insulin lispro. When should the medication be
given?
A. 1 hour before meals
B. At bedtime
C. Within 15 minutes of meals
D. 2 hours after meals
Correct Answer: C
Rationale: Insulin lispro is rapid-acting and should be administered immediately before
meals.
6. Which finding suggests digoxin toxicity?
A. Nausea and blurred vision
B. Increased appetite
C. Hypertension
D. Weight gain
Correct Answer: A
Rationale: Gastrointestinal symptoms and visual disturbances are common signs of
digoxin toxicity.
, 7. A client taking furosemide should be monitored for:
A. Hyperkalemia
B. Hypokalemia
C. Hypercalcemia
D. Hypermagnesemia
Correct Answer: B
Rationale: Furosemide is a loop diuretic that increases potassium excretion.
8. Which medication is commonly prescribed for acute angina?
A. Nitroglycerin
B. Digoxin
C. Warfarin
D. Furosemide
Correct Answer: A
Rationale: Nitroglycerin causes vasodilation and relieves myocardial ischemia.
9. A client taking nitroglycerin reports dizziness. The nurse recognizes this as:
A. An expected effect of vasodilation
B. Evidence of toxicity
C. Hyperglycemia
D. Infection
Correct Answer: A
Rationale: Vasodilation may lead to orthostatic hypotension and dizziness.
10. Which medication classification does albuterol belong to?
A. Beta2-adrenergic agonist
B. ACE inhibitor
C. Anticoagulant
D. Opioid analgesic
Correct Answer: A
Rationale: Albuterol is a short-acting beta2 agonist used for bronchodilation.
