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ATI PN Pharmacology Proctored Exam | Questions & Verified Answers | Comprehensive Practical Nursing Pharmacology Exam Review Study Guide PDF | 2026

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Prepare for your ATI PN Pharmacology Proctored Exam with this comprehensive study guide featuring exam questions and verified answers designed to strengthen your understanding of medication therapy, pharmacologic principles, and safe medication administration. This detailed review covers high-yield topics including pharmacokinetics and pharmacodynamics, medication calculations, dosage and administration, adverse effects, drug interactions, contraindications, patient education, medication safety, antibiotics, cardiovascular medications, respiratory medications, endocrine drugs, gastrointestinal medications, central nervous system medications, pain management, psychiatric medications, anticoagulants, insulin and other high-alert medications, and nursing responsibilities related to pharmacologic care. Ideal for practical nursing students, PN/LPN learners, ATI candidates, and NCLEX-PN students, this resource is perfect for preparing for ATI proctored exams, practice tests, quizzes, and pharmacology assessments while improving medication knowledge, strengthening clinical judgment, and maximizing exam readiness.

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ATI PN Pharmacology
Proctored Exam



(2025-2026)
Question and Answers
Expert Verified
(With A+ Grades Guarantee)

,Patient identifiers -Medical record number
-home telephone number



What lab values should a nurse monitor for a patient with ■ Urinalysis
chronic renal failure? ☐ Hematuria, proteinuria, and alterations in specific gravity
☐ Serum creatinine
- Gradual increase of 1 to 2 mg/dL per every 24 to 48 hr for acute renal
failure (ARF)
- Gradual increase over months to years for chronic renal failure (CRF)
exceeding 4 mg/dL
■ Blood urea nitrogen (BUN)
- 80 to 100 mg/dL within 1 week with ARF
- Gradual increase with elevated serum creatinine over months to years for
CRF
- 180-200 mg/dL with (CRF)
■ Serum electrolytes
- Decreased sodium (dilutional) and calcium, increased potassium,
phosphorus, and magnesium
■ Complete blood count (CBC)
- Decreased hemoglobin


What food should you increase when taking Lasix? -increased amounts of potassium-rich foods (e.g., bananas, prunes, raisins, and
orange juice)



Patient reports IV discomfort, what is your first action? color and temperature




Sumatriptan (treats migraine headaches) adverse effect pain, tightness, pressure, or heaviness in the chest, throat, neck, and/or jaw

slow or difficult speech


Know about Transdermal patch -• Apply at the same time once each day,
preferably in the morning. Keep patch on
for 12 to 14 hr each day.
• Remove the patch at night to reduce
the risk of developing tolerance to
nitroglycerin. Be medication-free a
minimum of 10 to 12 hr each day (usually
at night).
• Do not cut patches to ensure appropriate
dosage.
• Place the patch on a hairless area of skin
(chest, back, or abdomen) and rotate sites
to prevent skin irritation.
• Wash skin with soap and water and dry
thoroughly before applying new patch.


RBC Blood transfusion http://www.atitesting.com/ati_next_gen/FocusedReview/data/datacontext/RM%20A
MS%20RN%208.0%20Chp%2044.pdf (prime with normal saline and infuse with
sodium chloride).


What to understand about Parkinson's Meds? -they don't cure disease, they slow the process.




NEUPOGEN (filgrastim)-what is the appropriate route of administered by subcutaneous injection or IV infusion
this med?



Lisinopril therapeutic effect blood pressure answer (e.g. 120/80)

,Medication for Schizophrenia risperidone, Risperdal




Macrodantin medication used to treat or prevent certain urinary tract infections




Haldol-inform if you are taking ____________ medication. -benzodiazepine class of anti-anxiety drugs (all ending with "pam") and even,
Xanax.



Fosomax same as-Alendronate is used for treating osteoporosis in men and postmenopausal
women.



Lipitor -lowers cholesterol in blood, "statins". Reduce LDL and total cholesterol. Raise
HDL.



Garamycin- Antibiotic that is toxic to the kidney, injected for radiology studies.




Digoxin side effects -Fatigue
-Bradycardia
-Anorexia
-Nausea/Vomiting


Singulair used before exercise to prevent breathing problems during exercise
(bronchospasm).



What medication to administer with Tylenol overdose? acetylcysteine (Mucomyst) must be given IV




HPV vaccine Human Papilloma Virus (HPV2, HPV4) - -Three doses should be given over a 6
month
-interval for females at 11 to 12 years of age (minimum age is 9 years).
-The second dose should be administered 2 months after the first dose, and the
third dose should be administered 6 months after the first dose.
-HPV4 may be given to males starting at age 9 years of age.


Opioid toxicity-what to check first oxygen saturation




Valporic Acid lab liver




Lithium report immediately slurred speech




Prednisone report sore throat

, Food to avoid when taking Lithium -salty foods
-alcoholic beverages



Labs for patients taking hydrothiazide Periodic determination of serum electrolytes to detect possible electrolyte imbalance
should be done at appropriate intervals.



1) A nurse is caring for a client with hyperparathyroidism 3. Calcitonin (Miacalcin)
and notes that the client's serum calcium level is 13 mg/dL. Rationale:
Which medication should the nurse prepare to administer The normal serum calcium level is 8.6 to 10.0 mg/dL. This client is experiencing
as prescribed to the client? hypercalcemia. Calcium gluconate and calcium chloride are medications used for
1. Calcium chloride the treatment of tetany, which occurs as a result of acute hypocalcemia. In
2. Calcium gluconate hypercalcemia, large doses of vitamin D need to be avoided. Calcitonin, a thyroid
3. Calcitonin (Miacalcin) hormone, decreases the plasma calcium level by inhibiting bone resorption and
4. Large doses of vitamin D lowering the serum calcium concentration.


2.) Oral iron supplements are prescribed for a 6-year-old 4. Orange juice
child with iron deficiency anemia. The nurse instructs the Rationale:
mother to administer the iron with which best food item? Vitamin C increases the absorption of iron by the body. The mother should be
1. Milk instructed to administer the medication with a citrus fruit or a juice that is high in
2. Water vitamin C. Milk may affect absorption of the iron. Water will not assist in absorption.
3. Apple juice Orange juice contains a greater amount of vitamin C than apple juice.
4. Orange juice


3.) Salicylic acid is prescribed for a client with a diagnosis 1. Tinnitus
of psoriasis. The nurse monitors the client, knowing that Rationale:
which of the following would indicate the presence of Salicylic acid is absorbed readily through the skin, and systemic toxicity (salicylism)
systemic toxicity from this medication? can result. Symptoms include tinnitus, dizziness, hyperpnea, and psychological
1. Tinnitus disturbances. Constipation and diarrhea are not associated with salicylism.
2. Diarrhea
3. Constipation
4. Decreased respirations


4.) The camp nurse asks the children preparing to swim in 4. At least 30 minutes before exposure to the sun
the lake if they have applied sunscreen. The nurse Rationale:
reminds the children that chemical sunscreens are most Sunscreens are most effective when applied at least 30 minutes before exposure to
effective when applied: the sun so that they can penetrate the skin. All sunscreens should be reapplied after
1. Immediately before swimming swimming or sweating.
2. 15 minutes before exposure to the sun
3. Immediately before exposure to the sun
4. At least 30 minutes before exposure to the sun


5.) Mafenide acetate (Sulfamylon) is prescribed for the 3. Informing the client that this is normal
client with a burn injury. When applying the medication, the Rationale:
client complains of local discomfort and burning. Which of Mafenide acetate is bacteriostatic for gram-negative and gram-positive organisms
the following is the most appropriate nursing action? and is used to treat burns to reduce bacteria present in avascular tissues. The client
1. Notifying the registered nurse should be informed that the medication will cause local discomfort and burning and
2. Discontinuing the medication that this is a normal reaction; therefore options 1, 2, and 4 are incorrect
3. Informing the client that this is normal
4. Applying a thinner film than prescribed to the burn site


6.) The burn client is receiving treatments of topical 1.Hyperventilation
mafenide acetate (Sulfamylon) to the site of injury. The Rationale:
nurse monitors the client, knowing that which of the Mafenide acetate is a carbonic anhydrase inhibitor and can suppress renal
following indicates that a systemic effect has occurred? excretion of acid, thereby causing acidosis. Clients receiving this treatment should
1.Hyperventilation be monitored for signs of an acid-base imbalance (hyperventilation). If this occurs,
2.Elevated blood pressure the medication should be discontinued for 1 to 2 days. Options 3 and 4 describe
3.Local pain at the burn site local rather than systemic effects. An elevated blood pressure may be expected
4.Local rash at the burn site from the pain that occurs with a burn injury.


7.) Isotretinoin is prescribed for a client with severe acne. 2. Triglyceride level
Before the administration of this medication, the nurse Rationale:
anticipates that which laboratory test will be prescribed? Isotretinoin can elevate triglyceride levels. Blood triglyceride levels should be
1. Platelet count measured before treatment and periodically thereafter until the effect on the
2. Triglyceride level triglycerides has been evaluated. Options 1, 3, and 4 do not need to be monitored
3. Complete blood count specifically during this treatment.
4. White blood cell count

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