LANIF · 132 SRUN
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NURS 231 — Pathophysiology
P
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EST. 1972
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Portage Learning NURS 231 Pathophysiology
CO M P L E T E Q U E ST I O N S & CO R R E CT D E TA I L E D A N S W E RS
INSTITUTION Portage Learning PROGRAM Bachelor of Science in Nursing
COURSE CODE NURS 231 COURSE TITLE Pathophysiology
ACADEMIC YEAR EXAM TITLE Portage Learning NURS 231
Pathophysiology
TOTAL QUESTIONS 17 Questions FORMAT Multiple Choice — Select the
Single Best Answer
EXAMINATION INSTRUCTIONS
▸ Select the single best answer for each question.
▸ Pathophysiology concepts including cellular adaptation, inflammation, immunity, fluid and electrolyte
balance, acid-base disorders, cardiovascular, respiratory, renal, gastrointestinal, endocrine,
neurological, hematologic, musculoskeletal, and integumentary pathophysiology are all testable
content.
▸ Disease mechanisms, organ system disorders, and clinical applications are emphasized.
▸ Correct answers and clinical rationales appear below each question.
▸ All content reflects current evidence-based pathophysiological principles.
, SECTION I — PATHOPHYSIOLOGY: CORE CONCEPTS Questions 1 – 17
1. A patient presents with a condition characterized by decreased cell size and reduced
organ function. This cellular adaptation is most consistent with which of the following?
A. Hypertrophy
B. Hyperplasia
C. Atrophy
D. Metaplasia
CORRECT ANSWER C — Atrophy
RATIONALE Atrophy is a cellular adaptation characterized by a decrease in cell size and
reduced organ function. It can be caused by decreased workload, loss of
innervation, diminished blood supply, inadequate nutrition, or aging. This is a key
concept in pathophysiology that explains how cells adapt to changes in their
environment.
2. Which of the following best describes the inflammatory response?
A. A specific immune response targeting a particular pathogen
B. A non-specific response to tissue injury that includes vasodilation, increased vascular
permeability, and leukocyte infiltration
C. A response that only occurs in chronic disease states
D. A response that is mediated exclusively by B lymphocytes
CORRECT ANSWER B — A non-specific response to tissue injury that includes vasodilation,
increased vascular permeability, and leukocyte infiltration
RATIONALE The inflammatory response is a non-specific, innate immune response to tissue
injury. It involves vasodilation (causing redness and heat), increased vascular
permeability (causing swelling), and leukocyte infiltration (to remove pathogens
and debris). This response is fundamental to understanding pathophysiology and
disease processes.