1|Page
NR 546 / NR546 Actual Final Exam 2026 Prediction
questions (All correct answers, Already graded A)
MAOIs (monoamine oxidase inhibitors) affect which neurotransmitters?
A. Serotonin, Dopamine, Norepinephrine
B. Serotonin, GABA, Glutamate
C. Acetylcholine, Dopamine, Norepinephrine
D. Dopamine, GABA, Acetylcholine
A. Serotonin, Dopamine, Norepinephrine
Which of the following is considered first line treatment for depression?
A. SSRI
B. FGA
C. SNRI
D. MAOI
A. SSRI
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When treating a patient for major depression disorder which
medication would the PMHNP consider first?
A. Depakote
B. Selegiline
C. Escitalopram
D. Isocarboxazid
C. Escitalopram
Which of the following medication should be considered for a patient
diagnosed with major depressive disorder who reports "always
forgetting to take my pills"?
A. Mirtazapine
B. Fluvoxamine
C. Fluoxetine
D. Carbemazepine
C. Fluoxetine
Which of the following medication has a black box warning of a life-
threatening skin rash?
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A. Lithium
B. Lamotrigine
C. Lurasidone
D. Lorazepam
B. Lamotrigine
Which medication is considered the best tolerated SSRI?
A. Venlafaxine
B. Bupropion
C. Setraline
D. Escitalopram
D. Escitalopram
During a 4 week follow up appointment, Rashida, who is prescribed
Sertraline 25mg qAM reports slight improvement in depression
symptoms and tolerating medication well. Which of the following
should the PMHNP do?
A. Increase Setraline dose
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B. Switch to an SNRI
C. Switch to a different SSRI
D. Add Trazodone qHS for sleep.
A. Increase Setraline dose
Which medication should be avoided for the 66 year patient diagnosed
with major depressive disorder and anxiety with a reported fall 3
months ago?
A. Citalopram
B. Setraline
C. Paroxetine
D. Aripiprazole
C. Paroxetine
A patient reports upset stomach and diarrhea 3 days after taking new
prescription of sertraline. Which of the following is the most
appropriate response from the PMHNP?
A. "Start doubling the dose of sertraline and your symptoms will begin
to ease up".
NR 546 / NR546 Actual Final Exam 2026 Prediction
questions (All correct answers, Already graded A)
MAOIs (monoamine oxidase inhibitors) affect which neurotransmitters?
A. Serotonin, Dopamine, Norepinephrine
B. Serotonin, GABA, Glutamate
C. Acetylcholine, Dopamine, Norepinephrine
D. Dopamine, GABA, Acetylcholine
A. Serotonin, Dopamine, Norepinephrine
Which of the following is considered first line treatment for depression?
A. SSRI
B. FGA
C. SNRI
D. MAOI
A. SSRI
,2|Page
When treating a patient for major depression disorder which
medication would the PMHNP consider first?
A. Depakote
B. Selegiline
C. Escitalopram
D. Isocarboxazid
C. Escitalopram
Which of the following medication should be considered for a patient
diagnosed with major depressive disorder who reports "always
forgetting to take my pills"?
A. Mirtazapine
B. Fluvoxamine
C. Fluoxetine
D. Carbemazepine
C. Fluoxetine
Which of the following medication has a black box warning of a life-
threatening skin rash?
,3|Page
A. Lithium
B. Lamotrigine
C. Lurasidone
D. Lorazepam
B. Lamotrigine
Which medication is considered the best tolerated SSRI?
A. Venlafaxine
B. Bupropion
C. Setraline
D. Escitalopram
D. Escitalopram
During a 4 week follow up appointment, Rashida, who is prescribed
Sertraline 25mg qAM reports slight improvement in depression
symptoms and tolerating medication well. Which of the following
should the PMHNP do?
A. Increase Setraline dose
, 4|Page
B. Switch to an SNRI
C. Switch to a different SSRI
D. Add Trazodone qHS for sleep.
A. Increase Setraline dose
Which medication should be avoided for the 66 year patient diagnosed
with major depressive disorder and anxiety with a reported fall 3
months ago?
A. Citalopram
B. Setraline
C. Paroxetine
D. Aripiprazole
C. Paroxetine
A patient reports upset stomach and diarrhea 3 days after taking new
prescription of sertraline. Which of the following is the most
appropriate response from the PMHNP?
A. "Start doubling the dose of sertraline and your symptoms will begin
to ease up".
