Questions and Answers | latest Summer 2026-2027 – Galen.
NUR 210 Principles of Pharmacology Exam 1| Questions and
Answers | latest Summer 2026-2027 – Galen.
1. Which phase of pharmacokinetics involves the movement of a drug from the GI
tract into the vascular system?
o A. Distribution
o B. Metabolism
o C. Absorption
o D. Excretion
o Answer: C
2. Which organ is the primary site for drug metabolism?
o A. Kidneys
o B. Lungs
o C. Liver
o D. Spleen
o Answer: C
3. What is the normal laboratory range for serum Creatinine?
o A. 0.1 - 0.5 mg/dL
o B. 0.5 - 1.2 mg/dL
o C. 5.0 - 10.0 mg/dL
o D. 10 - 20 mg/dL
o Answer: B
4. Which laboratory value is the best indicator of the amount of urea nitrogen in the
blood, reflecting kidney function?
o A. Creatinine
o B. GFR
o C. ALT
o D. BUN
, o Answer: D
5. What is the normal range for Blood Urea Nitrogen (BUN)?
o A. 0.5 - 1.2 mg/dL
o B. 5 - 10 mg/dL
o C. 10 - 20 mg/dL
o D. 20 - 40 mg/dL
o Answer: C
6. The "First Pass Effect" primarily impacts the bioavailability of drugs administered
through which route?
o A. Intravenous
o B. Oral
o C. Subcutaneous
o D. Intramuscular
o Answer: B
7. Which term describes the amount of time required for the drug concentration in the
body to be reduced by 50%?
o A. Bioavailability
o B. Loading dose
o C. Half-life
o D. Peak level
o Answer: C
8. If two highly protein-bound drugs are administered simultaneously, what is the risk
to the patient?
o A. Decreased drug effectiveness
o B. Increased drug excretion
o C. Toxicity due to increased free drug in the system
o D. Improved therapeutic index
o Answer: C
,9. When is the most appropriate time to draw a "trough" level for a medication?
o A. 30 minutes after an IV dose
o B. Mid-way through the dosing schedule
o C. Immediately before the next scheduled dose
o D. 60 minutes after an oral dose
o Answer: C
10. Peak drug levels for a medication administered intravenously should be drawn at
what time?
o A. 10 minutes after administration
o B. 30–60 minutes after administration
o C. 2 hours after administration
o D. Just before the next dose
o Answer: B
11. Which of the following medications has a narrow therapeutic range and requires
close monitoring?
o A. Acetaminophen
o B. Phenytoin
o C. Ibuprofen
o D. Amoxicillin
o Answer: B
12. What is the specific antagonist used to reverse the effects of a benzodiazepine
overdose?
o A. Naloxone
o B. Acetylcysteine
o C. Vitamin K
o D. Flumazenil
o Answer: D
13. Which substance serves as the antagonist for Warfarin?
, o A. Protamine Sulfate
o B. Vitamin K
o C. Flumazenil
o D. Naloxone
o Answer: B
14. Which medication is the antagonist for opioid (opiate) drugs?
o A. Naloxone
o B. Vitamin K
o C. Acetylcysteine
o D. Protamine Sulfate
o Answer: A
15. What is the antidote for an overdose of Acetaminophen?
o A. Naloxone
o B. Flumazenil
o C. Acetylcysteine
o D. Vitamin K
o Answer: C
16. Red Man Syndrome is a potential adverse reaction associated with the rapid
infusion of which drug?
o A. Morphine
o B. Vancomycin
o C. Phenytoin
o D. Haloperidol
o Answer: B
17. Polypharmacy in geriatric patients is generally defined as the use of more than how
many drugs?
o A. 2
o B. 3