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NR 224 Exam 2 (2026) – 100+ Practice Questions & Answers on Oxygenation, Cardiovascular Function, Urinary Elimination, Wound Care & Oxygen Therapy | Chamberlain University

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Prepare confidently for NR 224 Exam 2 with this comprehensive collection of 100+ exam-style questions and answers developed for Chamberlain University nursing students. This study guide provides thorough coverage of essential nursing concepts, including oxygenation, ventilation, perfusion, pulmonary and cardiovascular assessment, ECG rhythm interpretation, oxygen delivery systems, urinary elimination, catheterization, pressure injury prevention and staging, wound assessment, wound healing, dressing selection, debridement techniques, heat and cold therapy, respiratory assessment, and cardiac output. Organized in an easy-to-review question-and-answer format, the document is ideal for reinforcing classroom learning, preparing for examinations, and mastering NCLEX-style nursing concepts. The material explains key respiratory physiology, including hypoxia, hypoxemia, hypoventilation, hyperventilation, lung expansion techniques, oxygen safety guidelines, CPAP and BiPAP therapy, oxygen delivery devices with corresponding flow rates and FiO₂ percentages, and common abnormal lung sounds. It also reviews cardiac conduction, ECG rhythms such as atrial fibrillation and ventricular tachycardia, factors affecting oxygenation, urinary disorders, catheter management, pressure injury staging, wound healing by primary, secondary, and tertiary intention, wound drainage characteristics, dressing types, debridement methods, and nursing interventions that promote safe, evidence-based patient care. The content aligns with foundational nursing concepts presented in leading nursing references and evidence-based clinical guidelines, including: Potter, P. A., Perry, A. G., Stockert, P. A., & Hall, A. M. Fundamentals of Nursing. Elsevier. Hinkle, J. L., & Cheever, K. H. Brunner & Suddarth's Textbook of Medical-Surgical Nursing. Wolters Kluwer. American Heart Association (AHA). Guidelines for CPR and Emergency Cardiovascular Care. National Pressure Injury Advisory Panel (NPIAP). Prevention and Treatment of Pressure Injuries: Clinical Practice Guideline. Relevant Students: Chamberlain University NR 224 students Bachelor of Science in Nursing (BSN) students Associate Degree in Nursing (ADN) students Practical/Vocational Nursing (LPN/LVN) students Fundamentals of Nursing students Adult Health Nursing students Medical-Surgical Nursing students Pre-licensure nursing students NCLEX-RN candidates Students preparing for nursing exams, quizzes, and clinical assessments Keywords: NR 224 Exam 2, NR224, Chamberlain University, nursing fundamentals, oxygenation, ventilation, perfusion, pulmonary system, hypoxia, hypoxemia, hypoventilation, hyperventilation, ECG interpretation, cardiac conduction, atrial fibrillation, ventricular tachycardia, ventricular fibrillation, asystole, cardiac output, stroke volume, oxygen therapy, nasal cannula, Venturi mask, nonrebreather mask, CPAP, BiPAP, respiratory assessment, lung sounds, crackles, wheezes, rhonchi, urinary elimination, urinary retention, urinary tract infection, urinary incontinence, catheterization, urinary diversion, pressure injuries, pressure ulcer staging, wound assessment, wound healing, wound drainage, debridement, wound dressings, hydrocolloid dressing, hydrogel dressing, oxygen safety, nursing interventions, NCLEX preparation, nursing exam questions, nursing study guide

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NR 224 Exam 2

ventilation - ANSWER ✔✔movement of air into and out of lungs,

regulation in aveoli


perfusion - ANSWER ✔✔ability of cardiovascular system to pump

oxygenated blood to tissues and return deoxygenated blood to lungs


pulmonary system - ANSWER ✔✔lungs, airways, chest walls, blood

vessels


hypoxia - ANSWER ✔✔low oxygen in tissues


hypoxemia - ANSWER ✔✔low oxygen in blood


hypoventilation - ANSWER ✔✔ventilation inadequate to meet oxygen

needs or eliminate enough CO2, caused by collapsed alveoli

,hyperventilation - ANSWER ✔✔increased respiratory rate which

causes excess CO2 elimination, anxiety/infection/drugs/acid-base

imbalance induce hyperventilation


conduction system - ANSWER ✔✔sinoatrial node, atrioventricular

node, bundle of His, Purkinje fibers


electrocardiogram (ECG) - ANSWER ✔✔ECG waveform (P wave,

QRS complex, T wave)


alterations of circulatory system - ANSWER ✔✔decreased cardiac

output (heart failure), myocardial ischemia (myocardial infarction),

impaired valvular function (obstructed blood flow, regurgitation), left-

sided heart failure (decreased cardiac output, pulmonary congestion),

right-sided heart failure (distended jugular veins, peripheral edema),

hypovolemia (decreased circulating blood flow)


sinus tachycardia - ANSWER ✔✔regular rhythm, fast rate of 100-180

bpm


sinus bradycardia - ANSWER ✔✔regular rhythm, slow rate of <60

bpm


atrial fibrillation - ANSWER ✔✔irregular ventricular response,

irregular cardiac rate of rhythm, no identifiable P wave

, ventricular tachycardia - ANSWER ✔✔slightly irregular rhythm with

rate of 100-200 bpm, absent P wave, wide and weird QRS complex


ventricular fibrillation - ANSWER ✔✔irregular and chaotic rhythm with

no discernible rate/waves, ventricular quivering, not pumping, immediate

resuscitation


asystole - ANSWER ✔✔absence of electrical activity, immediate

resuscitation


factors affecting oxygenation - ANSWER ✔✔decreased oxygen

carrying capacity (altered hemoglobin, i.e. anemia), decreased inspired

oxygen concentration (upper/lower airway obstruction, decreased

environmental oxygen-i.e. high altitudes, decreased delivery of inspired

oxygen), increased metabolic rate (fever), conditions affecting chest wall

movement (musculoskeletal abnormalities, nervous system diseases,

trauma)


nursing process: diagnosis (oxygenation) - ANSWER ✔✔activity

intolerance

ineffective airway clearance

ineffective breathing pattern

decreased cardiac output


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