PN 3003 MAT PED FINAL ASSESSMENT 2026
CLINICAL CASE STUDY QUESTIONS WITH
ANSWERS GRADED A+
◉ Osteogenesis Imperfecta Pathophysiology: Type 5.
Answer: Lamellar organization in an irregular mesh-like pattern
◉ Osteogenesis Imperfecta Pathophysiology: Type 6, 7, 8.
Answer: Normally developed Type I collagen fiber, but can't be
translated into bone
◉ Signs and symptoms of osteogenesis imperfecta.
Answer: Lax Joints
Weak Muscles
Osteoporosis
Recurrent Fractures
Bowing of Long Bones
Scoliosis
Blue Sclerae
Dentinogenesis Imperfecta
Deafness
,Hernias
Easy Bruising
Excessive Sweating
◉ OI progression.
Answer: Dependent upon Type
Dependent upon fracture management/healing
Growth patterns play a role in subsequent impairments
Many children use assistive devices for mobility
◉ OI medical mangement.
Answer: Biophosphonates inhibit osteoclast activity, decreasing
normal bone turnover
Vitamin D assists with calcium absorption
Bone marrow transplant may improve collagen and mineral content
Surgery: Intramedullary Rods: telescoping rods can be adjusted with
growth, Spinal Fusion
◉ OI PT evaluation.
Answer: History and Fracture History
Gross motor development/timing of milestones: Standardized
Assessment
,ROM/Strength: AROM is safer than passive, Caution with formal
MMT; observational assessment
Posture
Endurance
Gait/Mobility
Coordination/Balance
Pain
Assistive Devices/Bracing
◉ OI PT goals.
Answer: Family Education
Safe Weight Bearing
Aerobic Conditioning
Strengthening in a safe environment
Maximizing gait and functional independence
Interdisciplinary Approach
◉ OI PT Management.
Answer: Education on Fracture Care & Safe Handling
Age-Appropriate Developmental Skills
Weight bearing activities to improve bone density
Positioning: Seating, Standers
, Good skeletal alignment
Mobility: Alternative mobility early
Strengthening
Aerobic Activity
Maximize independent mobility and function
◉ OI Other interventions.
Answer: Whole Body Vibration (WBV)
Good results
Contraindicated in those with telescoping rods or joint subluxations
Aquatics
Safe, gravity-eliminated environment
◉ Arthogryposis multiplex congenital general points.
Answer: Congenital, non-progressive neuromuscular syndrome
Characterized by 2+ joint contractures, muscle weakness, and
fibrosis
Most severe contractures are at the ankle, knee and hip and are
bilateral
Also affects the UE but to a lesser degree
CLINICAL CASE STUDY QUESTIONS WITH
ANSWERS GRADED A+
◉ Osteogenesis Imperfecta Pathophysiology: Type 5.
Answer: Lamellar organization in an irregular mesh-like pattern
◉ Osteogenesis Imperfecta Pathophysiology: Type 6, 7, 8.
Answer: Normally developed Type I collagen fiber, but can't be
translated into bone
◉ Signs and symptoms of osteogenesis imperfecta.
Answer: Lax Joints
Weak Muscles
Osteoporosis
Recurrent Fractures
Bowing of Long Bones
Scoliosis
Blue Sclerae
Dentinogenesis Imperfecta
Deafness
,Hernias
Easy Bruising
Excessive Sweating
◉ OI progression.
Answer: Dependent upon Type
Dependent upon fracture management/healing
Growth patterns play a role in subsequent impairments
Many children use assistive devices for mobility
◉ OI medical mangement.
Answer: Biophosphonates inhibit osteoclast activity, decreasing
normal bone turnover
Vitamin D assists with calcium absorption
Bone marrow transplant may improve collagen and mineral content
Surgery: Intramedullary Rods: telescoping rods can be adjusted with
growth, Spinal Fusion
◉ OI PT evaluation.
Answer: History and Fracture History
Gross motor development/timing of milestones: Standardized
Assessment
,ROM/Strength: AROM is safer than passive, Caution with formal
MMT; observational assessment
Posture
Endurance
Gait/Mobility
Coordination/Balance
Pain
Assistive Devices/Bracing
◉ OI PT goals.
Answer: Family Education
Safe Weight Bearing
Aerobic Conditioning
Strengthening in a safe environment
Maximizing gait and functional independence
Interdisciplinary Approach
◉ OI PT Management.
Answer: Education on Fracture Care & Safe Handling
Age-Appropriate Developmental Skills
Weight bearing activities to improve bone density
Positioning: Seating, Standers
, Good skeletal alignment
Mobility: Alternative mobility early
Strengthening
Aerobic Activity
Maximize independent mobility and function
◉ OI Other interventions.
Answer: Whole Body Vibration (WBV)
Good results
Contraindicated in those with telescoping rods or joint subluxations
Aquatics
Safe, gravity-eliminated environment
◉ Arthogryposis multiplex congenital general points.
Answer: Congenital, non-progressive neuromuscular syndrome
Characterized by 2+ joint contractures, muscle weakness, and
fibrosis
Most severe contractures are at the ankle, knee and hip and are
bilateral
Also affects the UE but to a lesser degree
