HESI LPN to ADN Entrance Exam 2026 | 200 Practice Questions | HESI iNET for LPN to RN Bridge Programs

HESI LPN to ADN Entrance Exam 2026 | 200 Practice Questions | HESI
iNET for LPN to RN Bridge Programs
Section 1: Anatomy & Physiology

Question 1
Which structure in the heart is responsible for initiating the electrical impulse that causes the
atria to contract?
A) Atrioventricular (AV) node
B) Bundle of His
C) Purkinje fibers
D) Sinoatrial (SA) node
CORRECT ANSWER: D

Question 2
A client is diagnosed with metabolic acidosis. Which organ system is primarily responsible for
compensating for this acid-base imbalance?
A) Cardiovascular system
B) Endocrine system
C) Respiratory system
D) Renal system
CORRECT ANSWER: C

Question 3
The nurse is teaching a client about the functions of the liver. Which of the following is a
primary function of the liver?
A) Filtering waste products from the blood for excretion
B) Producing insulin to regulate blood glucose
C) Synthesizing clotting factors
D) Storing red blood cells
CORRECT ANSWER: C

Question 4
Oxygenated blood is returned to the left atrium of the heart via which vessels?
A) Pulmonary arteries
B) Pulmonary veins
C) Superior and inferior vena cava
D) Aorta
CORRECT ANSWER: B

Question 5
The glomerulus and Bowman's capsule are structural components of which organ?
A) Liver

,B) Spleen
C) Kidney
D) Gallbladder
CORRECT ANSWER: C

Question 6
Which hormone is secreted by the pancreas to lower blood glucose levels?
A) Glucagon
B) Insulin
C) Somatostatin
D) Amylase
CORRECT ANSWER: B

Question 7
Which part of the brain is responsible for regulating balance, coordination, and fine motor
movement?
A) Cerebrum
B) Cerebellum
C) Brainstem
D) Medulla oblongata
CORRECT ANSWER: B

Question 8
The nurse is caring for a client with a suspected fracture of the femur. Which type of bone
tissue forms the outer shell of the bone?
A) Spongy bone
B) Cancellous bone
C) Compact bone
D) Trabecular bone
CORRECT ANSWER: C

Question 9
In the digestive system, bile is produced by the liver and stored in which structure?
A) Pancreas
B) Duodenum
C) Gallbladder
D) Stomach
CORRECT ANSWER: C

Question 10
Which cellular organelle is responsible for the synthesis of proteins?
A) Mitochondria
B) Golgi apparatus

,C) Ribosomes
D) Lysosomes
CORRECT ANSWER: C

Question 11
A client's arterial blood gas results show pH 7.31, PaCO2 50 mm Hg, and HCO3 24 mEq/L.
Which condition is indicated by these values?
A) Metabolic acidosis
B) Metabolic alkalosis
C) Respiratory acidosis
D) Respiratory alkalosis
CORRECT ANSWER: C

Question 12
The normal resting heart rate for a healthy adult ranges from:
A) 40-60 beats per minute
B) 60-100 beats per minute
C) 80-120 beats per minute
D) 100-140 beats per minute
CORRECT ANSWER: B

Question 13
The nurse is assessing a client's pupils. Which cranial nerve is responsible for pupillary
constriction?
A) Cranial Nerve II (Optic)
B) Cranial Nerve III (Oculomotor)
C) Cranial Nerve IV (Trochlear)
D) Cranial Nerve VI (Abducens)
CORRECT ANSWER: B

Question 14
Which of the following is the primary site for nutrient absorption in the digestive system?
A) Stomach
B) Esophagus
C) Small intestine
D) Large intestine
CORRECT ANSWER: C

Question 15
What is the functional unit of the kidney?
A) Neuron
B) Nephron
C) Alveolus

, D) Villus
CORRECT ANSWER: B

Question 16
The nurse is reviewing the functions of the skeletal system. Which of the following is a
function of bones?
A) Regulation of body temperature
B) Production of red blood cells
C) Control of voluntary movement
D) Synthesis of vitamin D
CORRECT ANSWER: B

Question 17
Which layer of the skin is the outermost and provides a waterproof barrier?
A) Dermis
B) Hypodermis
C) Epidermis
D) Subcutaneous tissue
CORRECT ANSWER: C

Question 18
The mitral valve is located between which two chambers of the heart?
A) Right atrium and right ventricle
B) Left atrium and left ventricle
C) Right ventricle and pulmonary artery
D) Left ventricle and aorta
CORRECT ANSWER: B

Question 19
The hormone responsible for the reabsorption of water in the kidney's collecting ducts is:
A) Aldosterone
B) Antidiuretic hormone (ADH)
C) Atrial natriuretic peptide (ANP)
D) Parathyroid hormone (PTH)
CORRECT ANSWER: B

Question 20
In the process of gas exchange, oxygen moves from the alveoli into the pulmonary capillaries
through which mechanism?
A) Active transport
B) Osmosis
C) Diffusion