d
y d
y d
y d
y
dyEDITION McCANCE ALL CHAPTERS 1-50
dy dy dy dy
dyQUESTIONS & ANSWERS 2025.
dy dy dy
,Chapter 1-49 dy
Chapter01: Cellular Biology
dy dy dy
Rogers: McCance & Huether’s Pathophysiology, 9th Edition
dy dy dy dy dy dy
MULTIPLE CHOICE dy
1. Which statement best describes the cellular function of metabolic absorption?
dy dy dy dy dy dy dy dy dy
a. Cells can produce proteins. dy dy dy
b. Cells can secrete digestive dy dy dy
enzymes.
c. Cells can take in and use dy dy dy dy dy
nutrients.
d. Cells can synthesize fats. dy dy dy
ANS: d y C
In metabolic absorption, all cells take in and use nutrients and other
dy dy dy dy dy dy dy dy dy dy dy
substances from their surroundings. The remaining options are not
dy dy dy dy dy dy dy dy dy
inclusive in their descriptions of cellular metabolic absorption.
dy dy dy dy dy dy dy dy
DIF: Cognitive Level: Remembering dy dy
2. Where is most of a cell’s genetic information, including RNA and DNA,
dy dy dy dy dy dy dy dy dy dy dy
contained?
dy
a. Mitochond
ria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: d y C
The nucleus contains the nucleolus, a small dense structure composed
dy dy dy dy dy dy dy dy dy
largely of RNA, most of the cellular DNA, and the DNA-binding proteins, such
dy dy dy dy dy dy dy dy dy dy dy dy dy
as the histones, which regulate its activity. The mitochondria are
dy dy dy dy dy dy dy dy dy dy
responsible for cellular respiration and energy production.
dy dy dy dy dy dy dy
Ribosomes’ chief function is to provide sites for cellular protein synthesis. Lysosomes
dy dy dy dy dy dy dy dy dy dy dy
function as the intracellular digestive system.
dy dy dy dy dy dy
DIF: Cognitive Level: Remembering dy dy
3. Which component of the cell produces hydrogen peroxide (H2O2) by using
dy dy dy dy dy dy dy dy dy dy
oxygen to remove hydrogen atoms from specific substrates in an oxidative
dy dy dy dy dy dy dy dy dy dy dy
reaction?
dy
a. Lysosome
s
b. Peroxisom
, es
c. Ribosome
s
d. Endosome
ANS: d y B
, Peroxisomes are so named because they usually contain enzymes that use oxygen to
dy dy dy dy dy dy dy dy dy dy dy dy
remove hydrogen atoms from specific substrates in an oxidative reaction that
dy dy dy dy dy dy dy dy dy dy dy
produces H2O2, which is a powerful oxidant and potentially destructive if it
dy dy dy dy dy dy dy dy dy dy dy dy
accumulates or escapes from peroxisomes. Ribosomes are RNA-protein complexes
dy dy dy dy dy dy dy dy dy
(nucleoproteins) that are synthesized in the nucleolus and secreted into the
dy dy dy dy dy dy dy dy dy dy dy
cytoplasm through pores in the nuclear envelope called nuclear pore complexes.
dy dy dy dy dy dy dy dy dy dy dy
Lysosomes are saclike structures that originate from the Golgi complex and contain
dy dy dy dy dy dy dy dy dy dy dy
more than 40 digestive enzymes called hydrolases, which catalyze bonds in
dy dy dy dy dy dy dy dy dy dy dy
proteins, lipids, nucleic acids, and carbohydrates. An endosome is a vesical that has
dy dy dy dy dy dy dy dy dy dy dy dy dy
been pinched off from the cellular membrane.
dy dy dy dy dy dy dy
DIF: Cognitive Level: Remembering dy dy
4. Which cell component is capable of cellular autodigestion when it is
dy dy dy dy dy dy dy dy dy dy
released during cell injury?
dy dy dy dy
a. Ribosome
b. Golgi complex dy
c. Smooth endoplasmic dy
reticulum
d. Lysosomes
ANS: d y D
The lysosomal membrane acts as a protective shield between the powerful
dy dy dy dy dy dy dy dy dy dy
digestive enzymes within the lysosome and the cytoplasm, preventing
dy dy dy dy dy dy dy dy dy
their leakage into the cytoplasmic matrix. Disruption of the membrane by
dy dy dy dy dy dy dy dy dy dy dy
various treatments or cellular injury leads to a release of the lysosomal
dy dy dy dy dy dy dy dy dy dy dy dy
enzymes, which can then react with their specific substrates, causing
dy dy dy dy dy dy dy dy dy dy
cellular self- digestion. The chief function of a ribosome is to provide sites
dy dy dy dy dy dy dy dy dy dy dy dy dy
for cellular protein synthesis. The Golgi complex is a network of flattened,
dy dy dy dy dy dy dy dy dy dy dy dy
smooth vesicles and membranes often located near the cell nucleus. The
dy dy dy dy dy dy dy dy dy dy dy
smooth endoplasmic reticulum is involved in steroid hormone production
dy dy dy dy dy dy dy dy dy
and removing toxic substances from the cell.
dy dy dy dy dy dy dy
DIF: Cognitive Level: Remembering dy dy
5. Which cAMP-mediated response is related to antidiuretic hormone?
dy dy dy dy dy dy dy
a. Increased heart rate and force of dy dy dy dy dy
contraction
b. Secretion of cortisol dy dy
c. Increased retention of water dy dy dy
d. Breakdown of fat dy dy
ANS: d y C
Antidiuretic hormone leads to increased retention of water in the body. dy dy dy dy dy dy dy dy dy dy
Epinephrine causes increases in heart rate and force of contraction. Increased
dy dy dy dy dy dy dy dy dy dy dy
cortisol secretion is due to ACTH. Breakdown of fat is due to glucagon.
dy dy dy dy dy dy dy dy dy dy dy dy dy
DIF: Cognitive Level: Remembering dy dy
6. During which phase of the cell cycle is DNA synthesized?
dy dy dy dy dy dy dy dy dy