ACRP CP Exam Verified Exam Questions and Answers Latest update
2026/2027
Question:
IB
Answer:
Clinical and non-clinical data on the investigational product that is relevant to the study in human
subjects; supplied prior to regulatory approval
Question:
Study type - Open Label
Answer:
everyone knows the treatment
Question:
Study type - Single blind
Answer:
one party knows Tx, usually the patient does not know but the monitoring team does
Question:
Study type - Double Blind
Answer:
2 or more people are blinded, usually the patient and monitoring tram do not know which drug is
given. A 3rd party unblinded pharmacist is used and an unblinded CRA is needed
Question:
Study Type - Double dummy
Answer:
Use to blind similar Tx's; one is active and one is placebo. This occurs when the drug and placebo
cannot be made identical (pill vs liquid)
Question:
Study Type - Parallel
Answer:
Two groups of treatments. One group receives only treatment A and another group receives only
treatment B
, Question:
Study Type - Crossover
Answer:
Usually Chronic disease; receives more than one Tx with a washout in between. A then B; could be
randomized so the sequence changes
Question:
Define Overall Survival
Answer:
the length of time from treatment until time of death. In a clinical trial, measuring the overall survival
is one way to see how well a new treatment works.
Question:
Define Cohort
Answer:
Subjects are matched for similar groups; ex:
Smokers, sex and age
Question:
Study Type - Placebo control
Answer:
in addition to a group of subjects that receives the treatment to be evaluated, a separate control group
receives a placebo
Question:
Study Type - Active control
Answer:
Done when use of placebo is unethical like antibiotics studies. Means that a known, effective
treatment (as opposed to a placebo) is compared to an experimental treatment
Question:
Define Randomization
Answer:
method used to equify distribution of Tx to subjects; to eliminate bias
2026/2027
Question:
IB
Answer:
Clinical and non-clinical data on the investigational product that is relevant to the study in human
subjects; supplied prior to regulatory approval
Question:
Study type - Open Label
Answer:
everyone knows the treatment
Question:
Study type - Single blind
Answer:
one party knows Tx, usually the patient does not know but the monitoring team does
Question:
Study type - Double Blind
Answer:
2 or more people are blinded, usually the patient and monitoring tram do not know which drug is
given. A 3rd party unblinded pharmacist is used and an unblinded CRA is needed
Question:
Study Type - Double dummy
Answer:
Use to blind similar Tx's; one is active and one is placebo. This occurs when the drug and placebo
cannot be made identical (pill vs liquid)
Question:
Study Type - Parallel
Answer:
Two groups of treatments. One group receives only treatment A and another group receives only
treatment B
, Question:
Study Type - Crossover
Answer:
Usually Chronic disease; receives more than one Tx with a washout in between. A then B; could be
randomized so the sequence changes
Question:
Define Overall Survival
Answer:
the length of time from treatment until time of death. In a clinical trial, measuring the overall survival
is one way to see how well a new treatment works.
Question:
Define Cohort
Answer:
Subjects are matched for similar groups; ex:
Smokers, sex and age
Question:
Study Type - Placebo control
Answer:
in addition to a group of subjects that receives the treatment to be evaluated, a separate control group
receives a placebo
Question:
Study Type - Active control
Answer:
Done when use of placebo is unethical like antibiotics studies. Means that a known, effective
treatment (as opposed to a placebo) is compared to an experimental treatment
Question:
Define Randomization
Answer:
method used to equify distribution of Tx to subjects; to eliminate bias
