Pharmacotherapeutics for
Advanced Practice Nurse
Prescribers with Davis Edge
6th Edition
• Author(s)Teri Moser Woo; Wendy
L. Wright
TEST BANK
▪ The Foundation
▪ Pharmacotherapeutics with Single Drugs
▪ Pharmacotherapeutics with Multiple Drugs
▪ Special Drug Treatment Considerations
,Question 1
A family nurse practitioner is seeing a 56-year-old man with newly
diagnosed hypertension. Before selecting pharmacotherapy, the APRN
reviews the patient's medical history, current medications, allergies,
laboratory results, and home blood pressure log. Which prescribing
principle is best demonstrated?
A. Initiating treatment with the newest available antihypertensive
medication
B. Selecting medication based primarily on insurance formulary status
C. Performing a comprehensive patient assessment to individualize
therapy before prescribing
D. Prescribing combination therapy to achieve the fastest blood
pressure reduction
Correct Answer: C
Rationale:
A comprehensive assessment is the cornerstone of safe prescribing.
Reviewing the patient's diagnoses, medication history, allergies,
laboratory values, and clinical goals helps the APRN select the safest
and most effective medication while minimizing adverse drug events
and interactions. Formulary considerations are important but should
not supersede clinical appropriateness. Initiating the newest
medication without justification or using combination therapy without
an indication does not reflect evidence-based prescribing.
,Question 2
A 74-year-old woman with chronic kidney disease (estimated GFR 28
mL/min/1.73 m²) requires treatment with a medication that is primarily
eliminated by the kidneys. Which action by the APRN best reflects safe
prescribing practice?
A. Prescribe the standard adult dose because age has little effect on
drug clearance.
B. Reduce the dose or extend the dosing interval based on renal
function before initiating therapy.
C. Delay treatment until renal function returns to normal.
D. Double the loading dose to achieve therapeutic concentrations more
rapidly.
Correct Answer: B
Rationale:
Many medications require dosage adjustment in patients with impaired
renal function to reduce the risk of drug accumulation and toxicity.
APRNs should assess renal function before prescribing and modify
dosing according to current evidence and product-specific
recommendations. Standard dosing may result in adverse effects,
delaying necessary therapy is often inappropriate, and increasing the
loading dose may increase toxicity without improving long-term
therapeutic outcomes.
Question 3
A patient presents with a prescription for an oral antibiotic from an
urgent care clinic. During medication reconciliation, the APRN discovers
, the patient recently began taking warfarin prescribed by another
clinician. What is the APRN's best next action before initiating therapy?
A. Advise the patient to discontinue warfarin while taking the antibiotic.
B. Assess for potential drug interactions and determine whether an
alternative medication or additional monitoring is needed.
C. Instruct the patient to take both medications without further
evaluation because they were prescribed by different clinicians.
D. Recommend the patient stop the antibiotic until the infection
resolves spontaneously.
Correct Answer: B
Rationale:
Medication reconciliation is an essential component of safe prescribing.
Identifying potential drug-drug interactions before initiating therapy
helps prevent serious adverse events. Warfarin has numerous clinically
significant interactions, and the APRN should evaluate interaction
severity, determine whether an alternative medication is appropriate,
or implement enhanced monitoring when necessary. Abrupt
discontinuation of either medication without clinical justification may
place the patient at unnecessary risk.
Question 4
A pregnant patient at 10 weeks' gestation presents with symptoms
requiring pharmacologic treatment. Before prescribing, which principle
should guide the APRN's decision-making?
A. Avoid prescribing any medication during pregnancy regardless of
clinical necessity.
Advanced Practice Nurse
Prescribers with Davis Edge
6th Edition
• Author(s)Teri Moser Woo; Wendy
L. Wright
TEST BANK
▪ The Foundation
▪ Pharmacotherapeutics with Single Drugs
▪ Pharmacotherapeutics with Multiple Drugs
▪ Special Drug Treatment Considerations
,Question 1
A family nurse practitioner is seeing a 56-year-old man with newly
diagnosed hypertension. Before selecting pharmacotherapy, the APRN
reviews the patient's medical history, current medications, allergies,
laboratory results, and home blood pressure log. Which prescribing
principle is best demonstrated?
A. Initiating treatment with the newest available antihypertensive
medication
B. Selecting medication based primarily on insurance formulary status
C. Performing a comprehensive patient assessment to individualize
therapy before prescribing
D. Prescribing combination therapy to achieve the fastest blood
pressure reduction
Correct Answer: C
Rationale:
A comprehensive assessment is the cornerstone of safe prescribing.
Reviewing the patient's diagnoses, medication history, allergies,
laboratory values, and clinical goals helps the APRN select the safest
and most effective medication while minimizing adverse drug events
and interactions. Formulary considerations are important but should
not supersede clinical appropriateness. Initiating the newest
medication without justification or using combination therapy without
an indication does not reflect evidence-based prescribing.
,Question 2
A 74-year-old woman with chronic kidney disease (estimated GFR 28
mL/min/1.73 m²) requires treatment with a medication that is primarily
eliminated by the kidneys. Which action by the APRN best reflects safe
prescribing practice?
A. Prescribe the standard adult dose because age has little effect on
drug clearance.
B. Reduce the dose or extend the dosing interval based on renal
function before initiating therapy.
C. Delay treatment until renal function returns to normal.
D. Double the loading dose to achieve therapeutic concentrations more
rapidly.
Correct Answer: B
Rationale:
Many medications require dosage adjustment in patients with impaired
renal function to reduce the risk of drug accumulation and toxicity.
APRNs should assess renal function before prescribing and modify
dosing according to current evidence and product-specific
recommendations. Standard dosing may result in adverse effects,
delaying necessary therapy is often inappropriate, and increasing the
loading dose may increase toxicity without improving long-term
therapeutic outcomes.
Question 3
A patient presents with a prescription for an oral antibiotic from an
urgent care clinic. During medication reconciliation, the APRN discovers
, the patient recently began taking warfarin prescribed by another
clinician. What is the APRN's best next action before initiating therapy?
A. Advise the patient to discontinue warfarin while taking the antibiotic.
B. Assess for potential drug interactions and determine whether an
alternative medication or additional monitoring is needed.
C. Instruct the patient to take both medications without further
evaluation because they were prescribed by different clinicians.
D. Recommend the patient stop the antibiotic until the infection
resolves spontaneously.
Correct Answer: B
Rationale:
Medication reconciliation is an essential component of safe prescribing.
Identifying potential drug-drug interactions before initiating therapy
helps prevent serious adverse events. Warfarin has numerous clinically
significant interactions, and the APRN should evaluate interaction
severity, determine whether an alternative medication is appropriate,
or implement enhanced monitoring when necessary. Abrupt
discontinuation of either medication without clinical justification may
place the patient at unnecessary risk.
Question 4
A pregnant patient at 10 weeks' gestation presents with symptoms
requiring pharmacologic treatment. Before prescribing, which principle
should guide the APRN's decision-making?
A. Avoid prescribing any medication during pregnancy regardless of
clinical necessity.
