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NURS 663 Exam 1 Study Guide | 250+ Practice Questions on Bipolar Disorder, Major Depressive Disorder, Lithium, Antidepressants, Mood Stabilizers & Psychopharmacology | Maryville University

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Prepare confidently for Maryville University NURS 663 Exam 1 with this comprehensive study guide featuring 250+ exam-style practice questions and detailed answer explanations covering the essential concepts of advanced psychiatric mental health nursing, mood disorders, psychopharmacology, suicide risk assessment, and evidence-based treatment strategies. This resource provides an in-depth review of bipolar disorder, major depressive disorder (MDD), mania, hypomania, cyclothymic disorder, disruptive mood dysregulation disorder (DMDD), persistent depressive disorder (dysthymia), antidepressant therapy, mood stabilizers, lithium therapy, atypical antipsychotics, psychotherapy modalities, suicide assessment tools, and psychiatric diagnostic criteria. Organized in a structured question-and-answer format, this guide is designed to reinforce clinical reasoning, strengthen diagnostic accuracy, and improve examination performance for graduate nursing students. The study guide thoroughly reviews DSM-5 diagnostic criteria for mood disorders, Bipolar I disorder, bipolar versus unipolar depression, bipolar versus ADHD, major depressive disorder diagnostic criteria, SIGECAPS, SLAP suicide assessment, IS PATH WARM suicide warning signs, PHQ-9 screening, Child Mania Rating Scale, lithium pharmacology, therapeutic drug monitoring, lithium toxicity, laboratory monitoring, mood stabilizers including lamotrigine, valproate, carbamazepine, oxcarbazepine, selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), first-, second-, and third-generation antipsychotics, metabolic syndrome, extrapyramidal symptoms (EPS), pregnancy considerations, black box warnings, cognitive behavioral therapy (CBT), dialectical behavior therapy (DBT), interpersonal psychotherapy (IPT), eye movement desensitization and reprocessing (EMDR), treatment-resistant depression, suicide risk factors, psychiatric assessment, and evidence-based psychopharmacologic management of mood disorders. The realistic practice questions strengthen clinical judgment while preparing students for graduate-level psychiatric nursing examinations and advanced clinical practice. Designed for graduate nursing education, this study resource serves as an excellent companion for classroom examinations, certification preparation, clinical practicums, and comprehensive review. The detailed explanations reinforce pharmacologic principles, psychiatric assessment skills, differential diagnosis, and therapeutic decision-making required for safe, evidence-based mental health care across diverse patient populations. The content is aligned with current psychiatric nursing practice and evidence-based clinical guidelines presented in American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-5-TR). American Psychiatric Association Publishing; 2022, Stahl SM. Stahl's Essential Psychopharmacology. 5th ed. Cambridge University Press; 2021, Stahl SM. Prescriber's Guide. 8th ed. Cambridge University Press; 2025, Varcarolis EM. Essentials of Psychiatric Mental Health Nursing. 5th ed. Elsevier; 2024, Sadock BJ, Sadock VA, Ruiz P. Kaplan & Sadock's Synopsis of Psychiatry. 12th ed. Wolters Kluwer; 2021, and the American Psychiatric Association Practice Guidelines, which provide the scientific and clinical foundation for psychiatric diagnosis, psychopharmacology, and mental health treatment. Relevant Students: Maryville University NURS 663 students, Psychiatric Mental Health Nurse Practitioner (PMHNP) students, Master of Science in Nursing (MSN) students, Doctor of Nursing Practice (DNP) students, Advanced Practice Registered Nurse (APRN) students, Graduate nursing students, Psychiatric nursing students, Mental Health Nursing students, Nurse Practitioner students, Registered Nurse (RN) students, BSN students, Clinical Nurse Specialist (CNS) students, Physician Assistant (PA) students, Medical students, Psychology students, Behavioral Health students, Psychiatry residents, PMHNP certification candidates, ANCC PMHNP exam candidates, Advanced psychopharmacology students. Keywords NURS 663, Maryville University, NURS 663 Exam 1, Psychiatric mental health nursing, PMHNP, Psychopharmacology, Bipolar disorder, Bipolar I disorder, Major depressive disorder, MDD, Mania, Hypomania, Cyclothymic disorder, Persistent depressive disorder, Dysthymia, Disruptive Mood Dysregulation Disorder, Lithium, Lithium toxicity, Lithium monitoring, Mood stabilizers, Lamotrigine, Valproate, Carbamazepine, Oxcarbazepine, SSRIs, SNRIs, Antidepressants, Atypical antipsychotics, Second-generation antipsychotics, Third-generation antipsychotics, Metabolic syndrome, Extrapyramidal symptoms, Suicide assessment, Suicide risk factors, PHQ-9, SIGECAPS, IS PATH WARM, SLAP, CBT, DBT, IPT, EMDR, DSM-5-TR, Psychiatric assessment, Mood disorders, Mental health nursing, PMHNP exam preparation, Graduate nursing, Advanced psychiatric nursing

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Maryville Nurs 663 Exam 1
2026 Exam Questions and
Answers | Already Graded A+



Lithium labs - ANSWER ✔✔level, NA, Ca, P, EKG, Creatinine,

Urinalysis, CBC, TSH


bipolar meds: depression - ANSWER ✔✔lurasidone (13+),

olanzapine + fluoxetine (10+)(symbyax)


bipolar acute and mixed mania - ANSWER ✔✔aripiprazole,

risperidone, olanzapine (13+), quetiapine (acute only), asenapine (10+)


classic mood stabilizers - ANSWER ✔✔Lamotrigine (excellent

medication to use), lithium, Depakote (avoid in females if possible due to

,PCOS and Pregnancy), Tegretol, Trileptal (no evidence for true Bipolar

disorder)


anti-depressants - ANSWER ✔✔class not used w/bipolar disorder


lithium - ANSWER ✔✔Anti-manic, antidepressant, anti-suicidal


Lithium side effects - ANSWER ✔✔Frequent urination, increased

thirst, weight gain, sedation


lithium toxicity - ANSWER ✔✔sudden onset tremors, N/V/D, muscle

weakness, slurred speech, confusion, seizures (slowing down, feel really

out of it)


Major Depressive Disorder Dx - ANSWER ✔✔5+ for at least a 2-

week period; either #1 or 2 req

1. Depressed mood most of the day, nearly every day (can be irritability

in children & adolescents)

2. Diminished interest or pleasure in all, or almost all, activities

3. Change appetite/weight; kids not wt goals

Insomnia or hypersomnia nearly every day

4. Up or down Psychomotor

5. Fatigue or loss of energy

, 6. Worthlessness/excessive or inappropriate guilt

7. Diminished ability to think or concentrate, or indecisiveness (don't

confuse with ADHD, address mood first)

8. Recurrent thoughts of death, thoughts of suicide, or suicidal

plan/intent: if hosp then 2 wk not req.


SLAP - ANSWER ✔✔Social supports; lethal; access to means; plan

and previous attempt


Suicide risk: IS PATH WARM - ANSWER ✔✔Ideation, substance

abuse, purpose to live gone; anxiety, trapped feeling; hopelessness, w/d

from soc supports, anger w/rage; reckless, dramatic moods


SIGECAPS - ANSWER ✔✔Sleep, Interest, Guilt, Energy,

Concentration, Appetite, Psychomotor, Suicide


bipolar vs unipolar: look at bipolar if - ANSWER ✔✔1. family hx: 1st

degree relatives

2. Substance use: chasing high or low

3. Response to SSRI: no resp to multiple tries or evidence of mania with

use (not diagnostic)


Bipolar I criteria - ANSWER ✔✔One manic episode required



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