,BIOL251/BIOL 251 Module 5 Exam | Human Anatomy &
Physiology I w/ Lab | Portage Learning | Q & A | 2026/2027
(PDF)
**1. Which of the following terms describes the outermost layer of dense irregular connective tissue
that completely surrounds an entire skeletal muscle organ?**
A) Perimysium
B) Endomysium
C) Epimysium
D) Sarcolemma
Correct Answer: Epimysium
Rationale: The epimysium is the dense external connective tissue layer that envelopes the entire muscle
organ. The perimysium surrounds muscle fascicles (bundles of fibers), while the endomysium wraps
individual muscle fibers. The sarcolemma is the actual cell membrane of the muscle fiber, not a
connective tissue sheath.
**2. A bundle of individual skeletal muscle fibers wrapped together by a layer of connective tissue called
the perimysium is known as a:**
A) Myofibril
B) Fascicle
C) Sarcomere
D) Myofilament
Correct Answer: Fascicle
Rationale: A fascicle is a bundle of muscle fibers surrounded by the perimysium. Myofibrils are the
contractile organelles within muscle fibers, sarcomeres are the functional units of myofibrils, and
myofilaments are the protein filaments (actin and myosin) within sarcomeres.
**3. What are the four major functional characteristics of muscle tissue?**
,A) Contractibility, Excitability, Extensibility, and Elasticity
B) Contractibility, Conductivity, Extensibility, and Elasticity
C) Contractibility, Excitability, Extensibility, and Conductivity
D) Contractibility, Conductivity, Reactivity, and Elasticity
Correct Answer: Contractibility, Excitability, Extensibility, and Elasticity
Rationale: The four major functional characteristics of muscle tissue are contractibility (ability to
shorten), excitability (ability to respond to stimuli), extensibility (ability to be stretched), and elasticity
(ability to return to original shape). Conductivity and reactivity are not standard classifications for
muscle tissue properties.
**4. What are the three types of muscle tissue?**
A) Skeletal, Smooth, and Cardiac
B) Skeletal, Smooth, and Striated
C) Smooth, Cardiac, and Voluntary
D) Cardiac, Striated, and Involuntary
Correct Answer: Skeletal, Smooth, and Cardiac
Rationale: The three types of muscle tissue are skeletal (voluntary, striated), smooth (involuntary, non-
striated), and cardiac (involuntary, striated). Striated refers to appearance, not a separate tissue type,
and voluntary/involuntary describes control mechanisms.
**5. Which types of muscle tissue are under involuntary control?**
A) Skeletal and Cardiac
B) Smooth and Cardiac
C) Skeletal and Smooth
D) Skeletal only
, Correct Answer: Smooth and Cardiac
Rationale: Smooth and cardiac muscles are under involuntary control, meaning they function without
conscious effort. Skeletal muscle is under voluntary control. Cardiac muscle is found only in the heart,
while smooth muscle is found in the walls of hollow organs and blood vessels.
**6. Under the microscope, which types of muscle appear to be striated (striped) in appearance?**
A) Skeletal and Smooth
B) Smooth and Cardiac
C) Skeletal and Cardiac
D) Cardiac only
Correct Answer: Skeletal and Cardiac
Rationale: Both skeletal and cardiac muscle appear striated due to the organized arrangement of actin
and myosin filaments. Smooth muscle lacks striations and appears non-striated. The striations in cardiac
muscle are less organized than in skeletal muscle but are still visible.
**7. Muscle that is involuntary and has no striations is:**
A) Skeletal
B) Cardiac
C) Smooth
D) Striated
Correct Answer: Smooth
Rationale: Smooth muscle is involuntary and lacks striations. Skeletal muscle is voluntary and striated,
while cardiac muscle is involuntary but striated. Smooth muscle is found in the walls of hollow organs,
blood vessels, and the respiratory tract.
**8. Multinucleated, cylindrical muscle cells are characteristic of:**
Physiology I w/ Lab | Portage Learning | Q & A | 2026/2027
(PDF)
**1. Which of the following terms describes the outermost layer of dense irregular connective tissue
that completely surrounds an entire skeletal muscle organ?**
A) Perimysium
B) Endomysium
C) Epimysium
D) Sarcolemma
Correct Answer: Epimysium
Rationale: The epimysium is the dense external connective tissue layer that envelopes the entire muscle
organ. The perimysium surrounds muscle fascicles (bundles of fibers), while the endomysium wraps
individual muscle fibers. The sarcolemma is the actual cell membrane of the muscle fiber, not a
connective tissue sheath.
**2. A bundle of individual skeletal muscle fibers wrapped together by a layer of connective tissue called
the perimysium is known as a:**
A) Myofibril
B) Fascicle
C) Sarcomere
D) Myofilament
Correct Answer: Fascicle
Rationale: A fascicle is a bundle of muscle fibers surrounded by the perimysium. Myofibrils are the
contractile organelles within muscle fibers, sarcomeres are the functional units of myofibrils, and
myofilaments are the protein filaments (actin and myosin) within sarcomeres.
**3. What are the four major functional characteristics of muscle tissue?**
,A) Contractibility, Excitability, Extensibility, and Elasticity
B) Contractibility, Conductivity, Extensibility, and Elasticity
C) Contractibility, Excitability, Extensibility, and Conductivity
D) Contractibility, Conductivity, Reactivity, and Elasticity
Correct Answer: Contractibility, Excitability, Extensibility, and Elasticity
Rationale: The four major functional characteristics of muscle tissue are contractibility (ability to
shorten), excitability (ability to respond to stimuli), extensibility (ability to be stretched), and elasticity
(ability to return to original shape). Conductivity and reactivity are not standard classifications for
muscle tissue properties.
**4. What are the three types of muscle tissue?**
A) Skeletal, Smooth, and Cardiac
B) Skeletal, Smooth, and Striated
C) Smooth, Cardiac, and Voluntary
D) Cardiac, Striated, and Involuntary
Correct Answer: Skeletal, Smooth, and Cardiac
Rationale: The three types of muscle tissue are skeletal (voluntary, striated), smooth (involuntary, non-
striated), and cardiac (involuntary, striated). Striated refers to appearance, not a separate tissue type,
and voluntary/involuntary describes control mechanisms.
**5. Which types of muscle tissue are under involuntary control?**
A) Skeletal and Cardiac
B) Smooth and Cardiac
C) Skeletal and Smooth
D) Skeletal only
, Correct Answer: Smooth and Cardiac
Rationale: Smooth and cardiac muscles are under involuntary control, meaning they function without
conscious effort. Skeletal muscle is under voluntary control. Cardiac muscle is found only in the heart,
while smooth muscle is found in the walls of hollow organs and blood vessels.
**6. Under the microscope, which types of muscle appear to be striated (striped) in appearance?**
A) Skeletal and Smooth
B) Smooth and Cardiac
C) Skeletal and Cardiac
D) Cardiac only
Correct Answer: Skeletal and Cardiac
Rationale: Both skeletal and cardiac muscle appear striated due to the organized arrangement of actin
and myosin filaments. Smooth muscle lacks striations and appears non-striated. The striations in cardiac
muscle are less organized than in skeletal muscle but are still visible.
**7. Muscle that is involuntary and has no striations is:**
A) Skeletal
B) Cardiac
C) Smooth
D) Striated
Correct Answer: Smooth
Rationale: Smooth muscle is involuntary and lacks striations. Skeletal muscle is voluntary and striated,
while cardiac muscle is involuntary but striated. Smooth muscle is found in the walls of hollow organs,
blood vessels, and the respiratory tract.
**8. Multinucleated, cylindrical muscle cells are characteristic of:**
