2026 with NGN Comprehensive Practice Exam 100
Questions with Correct Answers & Detailed
Rationales | Updated 2026 | A+ Graded
SECTION 1: FUNDAMENTALS OF NURSING
1. A nurse is caring for a client experiencing shortness of breath. Which
assessment should be performed first?
• A) Obtain a blood pressure reading
• B) Assess oxygen saturation
• C) Check temperature
• D) Review laboratory results
Correct Answer: B
Rationale: Airway and breathing are the highest priorities in the ABCs (Airway,
Breathing, Circulation). Oxygen saturation helps determine the severity of
respiratory compromise and guides immediate interventions .
2. An oriented patient has recently had surgery. Which action is best for the
nurse to take to assess this patient's pain?
• A) Assess the patient's body language
• B) Ask the patient to rate the level of pain
• C) Observe the cardiac monitor for increased heart rate
• D) Have the patient describe the effect of pain on the ability to cope
,Correct Answer: B
Rationale: The most subjective and useful characteristic for reporting pain is its
severity. Asking the patient to rate pain is the most direct assessment method.
Nonverbal communication is less effective for oriented patients, and vital signs are
not specific to pain .
3. A client with heart failure is prescribed furosemide 40 mg IV twice daily.
Which assessment finding indicates the medication is effective?
• A) Decreased heart rate from 120 to 100 bpm
• B) Increased urine output from 30 mL/hr to 100 mL/hr
• C) Decreased blood pressure from 150/90 to 110/70 mmHg
• D) Increased respiratory rate from 20 to 24/min
Correct Answer: B
Rationale: Furosemide is a loop diuretic. Increased urine output indicates effective
diuresis, reducing fluid overload in heart failure .
4. A nurse is caring for a client with a new tracheostomy. Which action takes
priority?
• A) Suctioning when gurgling sounds are heard
• B) Cleaning the inner cannula every 8 hours
• C) Maintaining humidified oxygen
• D) Changing tracheostomy ties daily
Correct Answer: A
Rationale: Suctioning when gurgling sounds are heard is priority to maintain
airway patency and prevent aspiration .
,5. A client with COPD is receiving oxygen at 2 L/min via nasal cannula. The
client's family asks why the flow rate isn't higher. The nurse's response is based
on understanding that:
• A) Higher oxygen flows cause nasal dryness
• B) COPD clients may develop oxygen-induced hypoventilation
• C) Oxygen is toxic at higher concentrations
• D) Higher flows increase infection risk
Correct Answer: B
Rationale: Clients with severe COPD may have a hypoxic drive to breathe. High
oxygen levels can suppress this drive, leading to hypoventilation .
6. A nurse is assessing a client with possible deep vein thrombosis (DVT). Which
finding requires immediate intervention?
• A) Unilateral calf swelling
• B) Homans' sign positive
• C) Chest pain and dyspnea
• D) Warmth in affected leg
Correct Answer: C
Rationale: Chest pain and dyspnea suggest pulmonary embolism, a life-
threatening complication of DVT requiring immediate intervention .
7. A client with diabetes mellitus has a blood glucose of 55 mg/dL. The client is
conscious but confused. Which intervention should the nurse implement first?
• A) Administer 15 grams of fast-acting carbohydrates
• B) Administer glucagon IM
• C) Give 50% dextrose IV push
, • D) Notify the healthcare provider
Correct Answer: A
Rationale: For a conscious patient with hypoglycemia, the "Rule of 15" applies: 15
grams of fast-acting carbohydrates should be given first. Glucagon or IV dextrose
is for unconscious patients .
8. A client is receiving a blood transfusion and develops chills, fever, and back
pain. The nurse's first action should be to:
• A) Slow the infusion rate
• B) Administer diphenhydramine
• C) Stop the transfusion immediately
• D) Take vital signs
Correct Answer: C
Rationale: Chills, fever, and back pain suggest a hemolytic transfusion reaction.
Stop transfusion immediately to prevent further reaction .
9. A client with tuberculosis requires which type of isolation precaution?
• A) Contact
• B) Droplet
• C) Airborne
• D) Protective (reverse)
Correct Answer: C
Rationale: Tuberculosis requires airborne precautions, including a negative
pressure room, N95 respirator for healthcare workers, and an airborne sign on the
door .