Bio 315 EXAM 2 REVIEW QUESTIONS
AND ANSWERS
As they emerge from the ribosome, signal sequences are recognized and bound by a(n)
- CORRECT ANSWERS ✅✅ -signal recognition particle (SRP).
Arf function on vesicles is regulated by - CORRECT ANSWERS ✅✅ -binding of GTP
Using radiolabeled amino acids, Palade and colleagues defined the pathway taken by
secreted proteins. Which sequence represents that pathway? - CORRECT ANSWERS
✅✅ -Rough ER → Golgi → secretory vesicles → cell exterior
Which of the following would you expect to find at high concentrations in lysosomes? -
CORRECT ANSWERS ✅✅ -Degradative enzymes
The major site at which membrane lipids are synthesized is the - CORRECT
ANSWERS ✅✅ -cytosolic side of the ER membrane.
The ribosomes of the rough endoplasmic reticulum are targeted to the cytoplasmic side
of the membrane via - CORRECT ANSWERS ✅✅ -a sequence within the protein
being synthesized.
Membrane proteins are able to move - CORRECT ANSWERS ✅✅ -laterally within
the plane of a membrane
The pH of endosomes and lysosomes is - CORRECT ANSWERS ✅✅ -acidic
The glucose facilitated diffusion transporter can transport glucose - CORRECT
ANSWERS ✅✅ -into or out of the cell.
Which coat protein(s) would you expect to be recruited for vesicle formation by a KDEL
receptor? - CORRECT ANSWERS ✅✅ -COPI
The lumen of the ER is equivalent topologically to the - CORRECT ANSWERS ✅✅ -
extracellular space
Which of the following are integral membrane proteins that do not contain a
transmembrane αhelix? - CORRECT ANSWERS ✅✅ -Glycosylphosphatidylinositol
(GPI)-anchored proteins
AND ANSWERS
As they emerge from the ribosome, signal sequences are recognized and bound by a(n)
- CORRECT ANSWERS ✅✅ -signal recognition particle (SRP).
Arf function on vesicles is regulated by - CORRECT ANSWERS ✅✅ -binding of GTP
Using radiolabeled amino acids, Palade and colleagues defined the pathway taken by
secreted proteins. Which sequence represents that pathway? - CORRECT ANSWERS
✅✅ -Rough ER → Golgi → secretory vesicles → cell exterior
Which of the following would you expect to find at high concentrations in lysosomes? -
CORRECT ANSWERS ✅✅ -Degradative enzymes
The major site at which membrane lipids are synthesized is the - CORRECT
ANSWERS ✅✅ -cytosolic side of the ER membrane.
The ribosomes of the rough endoplasmic reticulum are targeted to the cytoplasmic side
of the membrane via - CORRECT ANSWERS ✅✅ -a sequence within the protein
being synthesized.
Membrane proteins are able to move - CORRECT ANSWERS ✅✅ -laterally within
the plane of a membrane
The pH of endosomes and lysosomes is - CORRECT ANSWERS ✅✅ -acidic
The glucose facilitated diffusion transporter can transport glucose - CORRECT
ANSWERS ✅✅ -into or out of the cell.
Which coat protein(s) would you expect to be recruited for vesicle formation by a KDEL
receptor? - CORRECT ANSWERS ✅✅ -COPI
The lumen of the ER is equivalent topologically to the - CORRECT ANSWERS ✅✅ -
extracellular space
Which of the following are integral membrane proteins that do not contain a
transmembrane αhelix? - CORRECT ANSWERS ✅✅ -Glycosylphosphatidylinositol
(GPI)-anchored proteins
