ACS ORGANIC CHEMISTRY II FINAL
2026 EXAMS, QUESTION AND
ANSWERS
What is the IUPAC priority for naming? - answerCarboxylic acid > Ketone > Aldehyde >
Alcohol
In IUPAC naming, what is the suffix used for ketone groups? - answer-one
In IUPAC naming, what is the suffix used for alcohol groups? - answer-nol
In IUPAC naming, what is the suffix used for esters? - answer-noate
Benzyl group - answer
Phenyl group - answer
ethanoic acid - answer
(E) isomers vs. (Z) isomers. Which one is observed when the higher ranked molecules
are on the same side? opposite? - answerhighest on same side: Z
highest on opposite sides: E
Electron-withdrawing groups are what type of directors? What is the one and only
exception? - answerMeta (deactivators)
Halogens
If the atom directly attached to the aromatic ring has lone pairs what type of director is
it? what if it does not have lone pairs? - answerlone pairs: activating, ortho, para director
no lone pairs: deactivating, meta director
When are the terms ortho, meta, para used? - answerwhen there are 2 substituents on
the aromatic ring
In IUPAC naming, what is NH2 on a phenyl ring referred to as? - answeraniline
Analine - answer
Amine - answer
Amide - answer
If there is a NO2 group present, what IUPAC prefix will also be evident? - answernitro
, What is the predicted reaction? 1º alkyl halide with a strong base? weak base? poor
nucleophile? - answerstrong base: Sn2 favored but E2 with strong non-nucleophilic
bases
weak base: Sn2
poor nucleophile: no reaction
What is the predicted reaction? 2º alkyl halide with a strong base? weak base? poor
nucleophile? - answerstrong base: mostly E2
strong non-nucleophilic bases: mostly Sn2
poor nucleophile: Sn1/E2 (slow) in polar, protic solvents
What is the predicted reaction? 3º alkyl halide with a strong base? weak base? poor
nucleophile? - answerstrong base: E2
strong non-nucleophilic bases: Sn1/E1 in polar protic solvents
poor nucleophile: Sn1/E1 in polar, protic solvents
What is the configuration of the product in the base-catalyzed hydrolysis of (R)-1-
choloro-1-deuteriobutane? - answer(S)-1-deuterio-1-butanol (Sn2)
Where is the largest molecule on the periodic table? - answerBottom lefthand corner
Nucleophilic strength increase with increasing what? - answeratomic size
Which alkyl valid would you expect to undergo Sn1 hydrolysis most rapidly?
I, Br,Cl, or F? - answerI
In which reaction is a racemic mixture obtained?
In which reaction is an inversion of chirality obtained? - answerinversion: Sn2
racemic mix: Sn1
Cleavage of an ether usually requires a strong acid that has a conjugate base which is a
strong nucleophile, such as...? Depending on the type of alkyl group, the acid reaction
with the halide ion produces what? - answerHBr
HI
alkyl halide and an alcohol
When chirality rotates clockwise the chirality is... - answerR
When chirality rotates counterclockwise the chirality is... - answerS
A solution containing equal amounts of both enantiomers is called a..? - answerracemic
mixture
A meso compound contains multiple __________ centers but is nevertheless ________
because it possesses reflection symmetry - answerchirality
2026 EXAMS, QUESTION AND
ANSWERS
What is the IUPAC priority for naming? - answerCarboxylic acid > Ketone > Aldehyde >
Alcohol
In IUPAC naming, what is the suffix used for ketone groups? - answer-one
In IUPAC naming, what is the suffix used for alcohol groups? - answer-nol
In IUPAC naming, what is the suffix used for esters? - answer-noate
Benzyl group - answer
Phenyl group - answer
ethanoic acid - answer
(E) isomers vs. (Z) isomers. Which one is observed when the higher ranked molecules
are on the same side? opposite? - answerhighest on same side: Z
highest on opposite sides: E
Electron-withdrawing groups are what type of directors? What is the one and only
exception? - answerMeta (deactivators)
Halogens
If the atom directly attached to the aromatic ring has lone pairs what type of director is
it? what if it does not have lone pairs? - answerlone pairs: activating, ortho, para director
no lone pairs: deactivating, meta director
When are the terms ortho, meta, para used? - answerwhen there are 2 substituents on
the aromatic ring
In IUPAC naming, what is NH2 on a phenyl ring referred to as? - answeraniline
Analine - answer
Amine - answer
Amide - answer
If there is a NO2 group present, what IUPAC prefix will also be evident? - answernitro
, What is the predicted reaction? 1º alkyl halide with a strong base? weak base? poor
nucleophile? - answerstrong base: Sn2 favored but E2 with strong non-nucleophilic
bases
weak base: Sn2
poor nucleophile: no reaction
What is the predicted reaction? 2º alkyl halide with a strong base? weak base? poor
nucleophile? - answerstrong base: mostly E2
strong non-nucleophilic bases: mostly Sn2
poor nucleophile: Sn1/E2 (slow) in polar, protic solvents
What is the predicted reaction? 3º alkyl halide with a strong base? weak base? poor
nucleophile? - answerstrong base: E2
strong non-nucleophilic bases: Sn1/E1 in polar protic solvents
poor nucleophile: Sn1/E1 in polar, protic solvents
What is the configuration of the product in the base-catalyzed hydrolysis of (R)-1-
choloro-1-deuteriobutane? - answer(S)-1-deuterio-1-butanol (Sn2)
Where is the largest molecule on the periodic table? - answerBottom lefthand corner
Nucleophilic strength increase with increasing what? - answeratomic size
Which alkyl valid would you expect to undergo Sn1 hydrolysis most rapidly?
I, Br,Cl, or F? - answerI
In which reaction is a racemic mixture obtained?
In which reaction is an inversion of chirality obtained? - answerinversion: Sn2
racemic mix: Sn1
Cleavage of an ether usually requires a strong acid that has a conjugate base which is a
strong nucleophile, such as...? Depending on the type of alkyl group, the acid reaction
with the halide ion produces what? - answerHBr
HI
alkyl halide and an alcohol
When chirality rotates clockwise the chirality is... - answerR
When chirality rotates counterclockwise the chirality is... - answerS
A solution containing equal amounts of both enantiomers is called a..? - answerracemic
mixture
A meso compound contains multiple __________ centers but is nevertheless ________
because it possesses reflection symmetry - answerchirality
