BIO 315: EXAM 1 MULTIPLE CHOICE
QUESTIONS WITH CORRECT ANSWERS
T/F: RNA Polymerase requires a DNA primer to begin Replication? - Correct Answers -
F
Which amino acid will always be at the N-terminus of newly translated proteins?
a.) Proline, Pro, P
b.) Arginine, Arg, R
c.) Alanine, Ala, A
d.) Methionine, Met, M
e.) Glycine, Gly, G - Correct Answers -d.) Methionine, Met, M.
This is translated from the start codon and starts every single protein.
Which of the following nucletotides will never be found in messenger RNA?
a.) UTP
b.) TTP
c.) CTP
d.) ATP - Correct Answers -b.) TTP
For a membrane protein, which of the following locations would you expect to find an
amino acid with a hydrophilic R-group (side chain)?
a.) Exposed to the hydrophobic lipid layer in the core of the membrane
b.) Packed to the center of the membrane domain of a protein, as far from the
hydrophobic lipid core as possible.
c.) Making salt bridges in the interior of the native folded protein
d.) Membrane proteins do not contain hydrophilic amino acids! - Correct Answers -b.)
Packed to the center of the membrane domain of a protein, as far from the hydrophobic
lipid core as possible.
For a cytosolic protein, which of the following locations would you expect to find an
amino acid with a charged R-group (side chain)?
a.) Making salt bridges in the interior of the native folded protein
b.) Exposed to the cytosol making hydrogen bonds with water
c.) Exposed to the hydrophobic interior of the lipid bilayer
, d.) On the interior of the natively folded protein - Correct Answers -b.) Exposed to the
cytosol making hydrogen bonds with water
If a cytosolilc protein cannot fold on its own, which of the following events could possibly
happen:
a.) The unfolded protein will be exported out of the cell.
b.) Large ATPases called chaperones will digest the protein down to component amino
acids.
c.) The hydrophobic sidechains of the unfolded protein will spontaneously clump with
other exposed hydrophobic patches to make an un-ordered protein aggreagate.
d.) Nothing, all proteins fold on their own. - Correct Answers -c.) The hydrophobic
sidechains of the unfolded protein will spontaneously clump with other exposed
hydrophobic patches to make an un-ordered protein aggreagate.
For a cytosolic protein, which of the following locations would you expect to find an
amino acid with a hydrophobic R-group (side chain):
a.) On the surface of the native folded protein
b.) Making hydrogen bonds on the surface of the native folded protein
c.) Making salt bridges in the interior of the native folded protein
d.) In the interior of the native folded protein - Correct Answers -d.) In the interior of the
native folded protein
T/F: RNA Polymerase can add ribonucleotides to the 5' end of a RNA strand. - Correct
Answers -False
Choose the option that best fills in the two blanks:
RNA is made from ______; DNA is made from ________ - Correct Answers -
ribonucleotides; deoxyribonucleotides
If a cytosolilc protein cannot fold on its own, which of the following events could possibly
happen:
a.) Small G-proteins will use the energy of GTP-hydrolysis to assist in the folding of the
proteins.
b.) Large ATPases called chaperones will attempt to assist in the folding of that protein.
QUESTIONS WITH CORRECT ANSWERS
T/F: RNA Polymerase requires a DNA primer to begin Replication? - Correct Answers -
F
Which amino acid will always be at the N-terminus of newly translated proteins?
a.) Proline, Pro, P
b.) Arginine, Arg, R
c.) Alanine, Ala, A
d.) Methionine, Met, M
e.) Glycine, Gly, G - Correct Answers -d.) Methionine, Met, M.
This is translated from the start codon and starts every single protein.
Which of the following nucletotides will never be found in messenger RNA?
a.) UTP
b.) TTP
c.) CTP
d.) ATP - Correct Answers -b.) TTP
For a membrane protein, which of the following locations would you expect to find an
amino acid with a hydrophilic R-group (side chain)?
a.) Exposed to the hydrophobic lipid layer in the core of the membrane
b.) Packed to the center of the membrane domain of a protein, as far from the
hydrophobic lipid core as possible.
c.) Making salt bridges in the interior of the native folded protein
d.) Membrane proteins do not contain hydrophilic amino acids! - Correct Answers -b.)
Packed to the center of the membrane domain of a protein, as far from the hydrophobic
lipid core as possible.
For a cytosolic protein, which of the following locations would you expect to find an
amino acid with a charged R-group (side chain)?
a.) Making salt bridges in the interior of the native folded protein
b.) Exposed to the cytosol making hydrogen bonds with water
c.) Exposed to the hydrophobic interior of the lipid bilayer
, d.) On the interior of the natively folded protein - Correct Answers -b.) Exposed to the
cytosol making hydrogen bonds with water
If a cytosolilc protein cannot fold on its own, which of the following events could possibly
happen:
a.) The unfolded protein will be exported out of the cell.
b.) Large ATPases called chaperones will digest the protein down to component amino
acids.
c.) The hydrophobic sidechains of the unfolded protein will spontaneously clump with
other exposed hydrophobic patches to make an un-ordered protein aggreagate.
d.) Nothing, all proteins fold on their own. - Correct Answers -c.) The hydrophobic
sidechains of the unfolded protein will spontaneously clump with other exposed
hydrophobic patches to make an un-ordered protein aggreagate.
For a cytosolic protein, which of the following locations would you expect to find an
amino acid with a hydrophobic R-group (side chain):
a.) On the surface of the native folded protein
b.) Making hydrogen bonds on the surface of the native folded protein
c.) Making salt bridges in the interior of the native folded protein
d.) In the interior of the native folded protein - Correct Answers -d.) In the interior of the
native folded protein
T/F: RNA Polymerase can add ribonucleotides to the 5' end of a RNA strand. - Correct
Answers -False
Choose the option that best fills in the two blanks:
RNA is made from ______; DNA is made from ________ - Correct Answers -
ribonucleotides; deoxyribonucleotides
If a cytosolilc protein cannot fold on its own, which of the following events could possibly
happen:
a.) Small G-proteins will use the energy of GTP-hydrolysis to assist in the folding of the
proteins.
b.) Large ATPases called chaperones will attempt to assist in the folding of that protein.
