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GCU NUR 635 midterm Questions and Answers Updated 2026

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GCU NUR 635 midterm Questions and Answers Updated 2026

Institution

NURS635 - NURS635

Course

NURS635 - NURS635

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GCU NUR 635 midterm
Questions and Answers
Updated 2026
PharmacokineticsBincludesB-BAnswerBabsorption,Bdistribution,Bmetabolism,Belimination

absorptionBofBdrugsBfactorsB-
BAnswerBPHBchanges,BgastricBemptying,BgastricBenzymes,BbileBacids,BGIBflora,BfoodBand
BnutrientBinteractions,BlipidBsolubility

WhereBisBcyp450BsystemBfoundB-BAnswerBendoplasmicBreticulumBofBhepatocytes

CYP3A4/5B-
BAnswerBmostBabundantBCYP450BisoformBwhichBmetabolizesBtheBmostBprescribed

"B"drugs.BEspeciallyBimportantBforBbioavailabilityBdueBtoBitsBabundanceBin

"B"cellsBliningBtheBGIBtract.BCanBbeBinducedBbyBaBwideBvarietyBofBdrugsB"

"andBisBpotentlyBinhibitedBbyBketoconazoleBandBerythromycin.

CYP2D6B-BAnswerBmetabolizesB25%BofBprescribedBdrugs

*3*4*5BmajorityBofBbadBmetabolizers

Antidepressants

Antipsychotics

Antiarrythmics

*carvedilol,B*metoprololB

*codeineB→Bmorphine

*tamoxifenBtoBactive

CYP2c8/9B-BAnswerBwarfarin

, CYP1A2B-BAnswerBAcetAminophen

CRAPBGPSBinducesBmyBrageB-BAnswerBcarbamazepine,Brifampin,

alcohol,Bphenytoin,Bgriseofulun,Bphenobarbitone,Bsulfonylureas

rectalBadminBhasBwhatBabsorptionB-BAnswerBvariableBandBerratic

steadyBstateB(SS)BisBusuallyBreachedBwithinBhowBmanyBhalf-livesBofBaBdrugB-
BAnswerB4-5

zero-order(nonlinear)BpharmacokineticsBmeansBaBdrugBisBmetabolizedB-
BAnswerBatBaBconstantBrateBperBunitBtime

Michaelis-mentenBpharmacokineticsB-
BAnswerBtheBrateBofBdrugBeliminationBisBdirectlyBproportionBtoBtheBconcentrationBofBfr
eeBdrugB(phenytoin)

theraputicBindexB-BAnswerBTD50B=BmedianBtoxicBdoseB

ED50B=BmedianBeffectiveBdose

windowB=BbetweenBthoseBdosesB

safeBdrugsBhaveBaBwiderBorBhighBwindow/index

AgonistB-
BAnswerBdrugsBthatBalterBtheBphysiologyBofBaBcellBbyBbindingBtoBplasmaBmembraneBor
BintracellularBreceptors

AntagonistsB(drugs)B-BAnswerBTheseBdrugsBblockBtheBactionsBcausedBbyBagonists

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Type: Exam (elaborations)
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GCU NUR 635 midterm Questions and Answers Updated 2026

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