NR 566 week 5 (Latest )
Advanced Pharmacology for Care of the
Family Questions & Answers {Grade A}
100% Correct – Chamberlain
When is it appropriate to prescribe and initiate androgen therapy for delayed puberty?
- Correct answer In some, puberty fails at the usual age (i.e., before age 15 years).
Often, failure reflects familial pattern of delayed puberty and does not indicate
pathology. Puberty can be expected to occur spontaneously but later than usual. Hence
treatment aint absolute necessity.
Why might a NP prescribe androgen therapy off label? - Correct answer the
psychologic pressures of delayed sexual maturation are causing a boy significant
distress. In these cases, a limited course of androgen therapy is indicated. Both
fluoxymesterone (Androxy, Halotestin) and methyltestosterone (Methitest) are
approved for this purpose.
,If delayed puberty is the result of true hypogonadism... - Correct answer long-term
replacement therapy is indicated (see later section titled Androgen Preparations for
Male Hypogonadism).
Androgen replacement therapy is indicated for when testicle failure occurs. What are
the benefits? - Correct answer Restores libido
Increases ejaculatory volume
Secondary sex characteristics
WILL NOT RESTORE FERTILITY
Two main drugs for androgen replacement therapy are... - Correct answer
testosterone enanthate and
testosterone cypionate
Regarding androgen therapy, two drugs are approved for delayed puberty. What are
they? - Correct answer fluoxymesterone (Androxy, Halotestin) and
methyltestosterone (Methitest)
,Testosterone therapy in menopausal women (NOT IN THE U.S/BUT IS APPROVEDIN
U.K) Helps to alleviate... - Correct answer Fatigue
Reduce libido
Reduced genital sensitivity
In women, testosterone therapy should mimic premenopause testosterone at what
strength? - Correct answer 300ug/day
Regarding andreogen therapy &
Cachexia (wasting of the body/failure to thrive)
Oxandrolone (Oxandrin) is... - Correct answer FDA-approved for this purpose.
Oxandrolone is an anabolic steroid that is a synthetic derivative of testosterone.
OXANDROLONE has BLACKBOX WARNING OF... - Correct answer Oxandrolone can
cause peliosis hepatitis, a condition in which blood-filled cysts form in the liver,
leading to liver failure or intra-abdominal hemorrhage. It can also contribute to the
development of highly vascular liver tumors.
, An increased risk for atherosclerosis can occur secondary to marked elevations in
low-density lipoprotein (LDL) and decreases in high-density lipoprotein (HDL).
Regarding androgen therapy, this therapy can help with anemia. What types of anemia
does this therapy help? - Correct answer Aplastic anemia, renal failure, fanconi
anemia, cancer assocaited
Androgen therapy helps with anemia by doing what? - Correct answer Promote synth
of erythropoetin
With the emergence of other therapies such as erythropoietin-stimulating agents,
however, androgens have fallen out of favor for off-label treatment of anemia.
Drug therapy for transgender men - Correct answer although not approved by the FDA
for this purpose, testosterone is prescribed off label as part of gender-affirmation
drug therapy.
Advanced Pharmacology for Care of the
Family Questions & Answers {Grade A}
100% Correct – Chamberlain
When is it appropriate to prescribe and initiate androgen therapy for delayed puberty?
- Correct answer In some, puberty fails at the usual age (i.e., before age 15 years).
Often, failure reflects familial pattern of delayed puberty and does not indicate
pathology. Puberty can be expected to occur spontaneously but later than usual. Hence
treatment aint absolute necessity.
Why might a NP prescribe androgen therapy off label? - Correct answer the
psychologic pressures of delayed sexual maturation are causing a boy significant
distress. In these cases, a limited course of androgen therapy is indicated. Both
fluoxymesterone (Androxy, Halotestin) and methyltestosterone (Methitest) are
approved for this purpose.
,If delayed puberty is the result of true hypogonadism... - Correct answer long-term
replacement therapy is indicated (see later section titled Androgen Preparations for
Male Hypogonadism).
Androgen replacement therapy is indicated for when testicle failure occurs. What are
the benefits? - Correct answer Restores libido
Increases ejaculatory volume
Secondary sex characteristics
WILL NOT RESTORE FERTILITY
Two main drugs for androgen replacement therapy are... - Correct answer
testosterone enanthate and
testosterone cypionate
Regarding androgen therapy, two drugs are approved for delayed puberty. What are
they? - Correct answer fluoxymesterone (Androxy, Halotestin) and
methyltestosterone (Methitest)
,Testosterone therapy in menopausal women (NOT IN THE U.S/BUT IS APPROVEDIN
U.K) Helps to alleviate... - Correct answer Fatigue
Reduce libido
Reduced genital sensitivity
In women, testosterone therapy should mimic premenopause testosterone at what
strength? - Correct answer 300ug/day
Regarding andreogen therapy &
Cachexia (wasting of the body/failure to thrive)
Oxandrolone (Oxandrin) is... - Correct answer FDA-approved for this purpose.
Oxandrolone is an anabolic steroid that is a synthetic derivative of testosterone.
OXANDROLONE has BLACKBOX WARNING OF... - Correct answer Oxandrolone can
cause peliosis hepatitis, a condition in which blood-filled cysts form in the liver,
leading to liver failure or intra-abdominal hemorrhage. It can also contribute to the
development of highly vascular liver tumors.
, An increased risk for atherosclerosis can occur secondary to marked elevations in
low-density lipoprotein (LDL) and decreases in high-density lipoprotein (HDL).
Regarding androgen therapy, this therapy can help with anemia. What types of anemia
does this therapy help? - Correct answer Aplastic anemia, renal failure, fanconi
anemia, cancer assocaited
Androgen therapy helps with anemia by doing what? - Correct answer Promote synth
of erythropoetin
With the emergence of other therapies such as erythropoietin-stimulating agents,
however, androgens have fallen out of favor for off-label treatment of anemia.
Drug therapy for transgender men - Correct answer although not approved by the FDA
for this purpose, testosterone is prescribed off label as part of gender-affirmation
drug therapy.
