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HESI A2 Biology Exam Questions (Latest 2026/2027 Update) | Complete Q&A with Verified Answers and Detailed Rationales | Cell Biology, Genetics, Photosynthesis | A+ Graded

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INSTANT PDF DOWNLOAD – This comprehensive study guide covers HESI A2 Biology Questions 81-369 for the 2026/2027 exam cycle, featuring 250+ verified questions with correct answers and detailed rationales . This resource covers the full spectrum of HESI A2 Biology content including cellular respiration and the electron transport chain (ETC) producing the greatest amount of ATP , photosynthesis requiring water as a raw material for light reactions , enzyme function and protein structure , osmosis and hypertonic solutions , and the Krebs cycle . Also includes questions on DNA replication, transcription , mitosis and meiosis (meiosis produces gametes with 23 chromosomes) , genetics and Punnett squares , and biological macromolecules (proteins are polymers of amino acids) . Aligned with the HESI Admission Assessment Exam Review, 6th Edition . HESI A2 Biology Questions 81 to 369 HESI A2 Biology Exam Prep Electron Transport Chain Most ATP Glycolysis First Step Glucose to Pyruvate Krebs Cycle Mitochondria Cellular Respiration Photosynthesis Water Raw Material Light Reactions Enzyme Protein Catalyst DNA Transcription RNA Synthesis Codon Anticodon Protein Synthesis Meiosis Gametes 23 Chromosomes Mitosis Body Cells 46 Chromosomes Punnett Square Polydactylism 75 Percent Hemophilia Sex Linked 25 Percent Carriers Osmosis Hypertonic Solution Cell Shrinks ATP Active Transport Energy Smooth ER Detoxification Organelle Mitochondria Heart Muscle High Proportion Nucleic Acids Inheritance Molecules Saturated Fats Hydrogen Atoms A+ Grade HESI A2 Study Guide

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Chamberlain University




OIB · 2A ISEH
★ ★


College of Nursing & Public Health
C
A C A D E M I C E X C E L L E N C E · I N N O V AT I O N · I N T E G R I T Y · W O R L D C L A S S
EST. 1889
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Hesi A2 Biology — Continued (Questions 81-369)
B I O LO G Y — CO M P R E H E N S I V E R E V I E W

INSTITUTION Chamberlain University PROGRAM Pre-Nursing / Allied Health
COURSE CODE HESI A2 COURSE TITLE Biology
ACADEMIC YEAR EXAM TITLE Hesi A2 Biology
TOTAL QUESTIONS 369 Questions (Continued from FORMAT Multiple Choice — Select the
Q81) Single Best Answer


EXAMINATION INSTRUCTIONS — CONTINUED
▸ Select the single best answer for each biology question.
▸ Topics include cell biology, genetics, metabolism, and plant biology.
▸ Focus on understanding key concepts and processes.
▸ Correct answers and rationales appear below each question.
▸ This is a continuation of the comprehensive HESI A2 biology review.

, SECTION I — BIOLOGY: CELLS, GENETICS, METABOLISM
Questions 81 – 369
& MORE (CONTINUED)

81. The diffusion of water through a semipermeable membrane is known as?
A. Osmosis
B. Diffusion
C. Active transport
D. Facilitated diffusion
CORRECT ANSWER A — Osmosis
RATIONALE Osmosis is the diffusion of water through a semipermeable membrane. It is the
movement of water from an area of high water concentration to low water
concentration.


82. The process in which carbon dioxide and water are combined under the influence of light
in green plants is called?
A. Photosynthesis
B. Cellular respiration
C. Fermentation
D. Glycolysis
CORRECT ANSWER A — Photosynthesis
RATIONALE Photosynthesis is the process in which carbon dioxide and water are combined
under the influence of light in green plants to produce glucose and oxygen. This is
the fundamental energy-capturing process for most life on Earth.

, 83. A protein substance that initiates and accelerates a chemical reaction is called?
A. Enzyme
B. Hormone
C. Vitamin
D. Mineral
CORRECT ANSWER A — Enzyme
RATIONALE An enzyme is a protein substance that initiates and accelerates chemical reactions
by lowering the activation energy. Enzymes are biological catalysts that are
essential for life.

84. The body's continual response to changes in the external and internal environment is
called?
A. Homeostasis
B. Metabolism
C. Excretion
D. Adaptation
CORRECT ANSWER A — Homeostasis
RATIONALE Homeostasis is the body's continual response to changes in the external and
internal environment to maintain stable internal conditions. It involves feedback
mechanisms that regulate temperature, pH, blood sugar, and other variables.

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