Summary Drugs Affecting Coagulation (Anticoagulants, Antiplatelets, Thrombolytics) updated 2026

TheseBgroupsBofBdrugsBaffectBclotBformationBandBresolutionBbyBhinderingBdifferentBste
psBinBclottingBformationBwhichBincludeBalteringBtheBformationBofBplateletBplugB(antipla
teletBdrugs),BinterferingBtheBclottingBcascadeBandBthrombinBformationB(anticoagulantBd
rugs),BandBstimulatingBtheBplasminBsystemBtoBbreakBdownBtheBformedBclotB(thromboly
ticBagents).

CoagulationBDrugs:BGenericBandBBrandBNames

HereBisBaBtableBofBcommonlyBencounteredBantiplatelet,Banticoagulant,BandBthrombolyti
cBagents,BtheirBgenericBnames,BandBbrandBnames:

• AntiplateletBAgents

• acetylsalicylicBacidB(Aspirin,BAsproBClear,BDisprin,BBayerBAspirin)

• cilostazolB(Pletal)

• dipyridamoleB(Persantine)

• tirofibanB(Aggrastat)

• Anticoagulants

• warfarinB(Coumadin)

• dabigatranB(Pradaxa)

• rivaroxabanB(Xarelto)

• ThrombolyticBAgents

, • alteplaseB(Activase)

• reteplaseB(Retavase)

• tenecteplaseB(TNKase)

• urokinaseB(Abbokinase)

• Low-molecular-weightBHeparins

• dalteparinB(Fragmin)

• enoxaparinB(Lovenox)

• tinzaparinB(Innohep)

• AnticoagulantBAdjunctiveBTherapy

• lepirudinB(Refludan)

• protamineBsulfate

• vitaminBK

• HemorrheologicBAgent

• pentoxifyllineB(Trental)

DiseaseBSpotlight:BThromboembolicBandBHemorrhagicBDisorders

DisordersBthatBdirectlyBaffectBcoagulationBprocessBareBdividedBintoBtwoBmainBcategorie
s:B1)BthromboembolicBdisorders,BwhichBinvolveBoverproductionBofBclots;BandB2)Bhemo
rrhagicBdisorders,BwhichBisBcharacterizedBbyBineffectiveBclottingBprocessBleadingBtoBexc
essiveBbleeding.

ThromboembolicBdisordersBincludeBmedicalBconditionsB(e.g.BCAD)BwhichBinvolveBoverpr
oductionBofBclotsBwhichBresultBintoBdecreasedBbloodBflowBandBtotalBvesselBocclusion.B
ManifestationsBincludeBhypoxia,Banoxia,BandBevenBnecrosis.BTheseBdisordersBareBtreate
dBbyBdrugsBthatBinterfereBwithBnormalBcoagulationBprocessBtoBpreventBformationBofBcl
ots.

OnBtheBotherBhand,BlessBcommonBhemorrhagicBdisordersBisBcharacterizedBbyBexcessiv
eBbleeding.BTheseBareBtreatedBbyBdrugsBthatBpromoteBtheBclottingBprocess.BSomeBofBt
heseBconditionsBinclude:

• Hemophilia:BcharacterizedBbyBgeneticBlackBofBclottingBfactors

• LiverBdisease:BcharacterizedBbyBnon-
productionBofBproteinsBandBclottingBfactorsBnecessaryBforBclotBformation