NR507 Advanced Pathophysiology Midterm Exam
Question With Answers|Chamberlain University
Question 1
What is the most abundant class of plasma protein?
Globulin
Albumin
Clotting factors
Complement proteins
Albumin (approximately 60% of total plasma protein at a concentration of
about 4 g/dl) is the most abundant plasma protein. NR507 Advanced
Pathophysiology midterm exam question with answers.
Question 2
Carcinoma in situ is characterized by which changes?
Cells have broken through the local basement membrane.
Cells have invaded immediate surrounding tissue.
Cells remain localized in the glandular or squamous cells.
Cellular and tissue alterations indicate dysplasia.
Carcinoma in situ (CIS) refers to preinvasive epithelial malignant tumors of
glandular or squamous cell origin. These early stage cancers are localized to
the epithelium and have not broken through the local basement membrane
or invaded the surrounding tissue. Dysplasia refers to changes in mature cell
structure.
Question 3
Which laboratory test is considered adequate for an accurate and
reliable diagnosis of gonococcal urethritis in a symptomatic man?
,Ligase chain reaction (LCR)
Gram-stain technique
Polymerase chain reaction (PCR)
DNA testing
Microscopic evaluation of Gram-stained slides of clinical specimens is
deemed positive for Neisseria gonorrhoeae if gram-negative diplococci with
the typical “kidney bean” morphologic appearance are found inside
polymorphonuclear leukocytes. Such a finding is considered adequate for the
diagnosis of gonococcal urethritis in a symptomatic man. The other options
are not relevant to the diagnosis of this condition.
Question 4
The Papanicolaou (Pap) test is used to screen for which cancer?
Ovarian
Uterine
Cervical
Vaginal
The Pap test, an examination of cervical epithelial scrapings, readily detects
early oncogenic human papillomavirus (HPV)infection. The Pap test is not
used for screening the other cancer sites listed.
Question 5
pts
Causes of hyperkalemia include:
Hyperparathyroidism and malnutrition
,Vomiting and diarrhea
Renal failure and Addison disease
Hyperaldosteronism and Cushing disease
NR507 Advanced Pathophysiology midterm exam question with answers
Hyperkalemia should be investigated when a history of renal disease,
massive trauma, insulin deficiency, Addison disease, use of potassium salt
substitutes, or metabolic acidosis exists. The other options are not known to
be causes of hyperkalemia.
Question 6
pts
What is the major concern regarding the treatment of gonococci infections?
Development of antibiotic resistance
Changes in virulence
Changes in pathogenicity
Mutations into different strains
, Several types of drug-resistant strains have been identified; they are
penicillinase-producing Neisseria gonorrhoeae (PPNG), which is resistant to
penicillin; tetracycline-resistant N. gonorrhoeae (TRNG), which is resistant to
tetracycline; chromosomal control of mechanisms of resistance of N.
gonorrhoeae (CMRNG), which is resistant to penicillin and tetracycline; and
increasingly a fluoroquinolone-resistant N. gonorrhoeae (QRNG). The other
options are not major concerns. NR507 Advanced Pathophysiology midterm
exam question with answers.
Question 7
pts
Hypersensitivity is best defined as a(an):
Disturbance in the immunologic tolerance of self-antigens
Immunologic reaction of one person to the tissue of another person
Altered immunologic response to an antigen that results in disease
Undetectable immune response in the presence of antigens
Hypersensitivity is an altered immunologic response to an antigen that
results in disease or damage to the host. The other options are not accurate
definitions of hypersensitivity.
Question 8
Question With Answers|Chamberlain University
Question 1
What is the most abundant class of plasma protein?
Globulin
Albumin
Clotting factors
Complement proteins
Albumin (approximately 60% of total plasma protein at a concentration of
about 4 g/dl) is the most abundant plasma protein. NR507 Advanced
Pathophysiology midterm exam question with answers.
Question 2
Carcinoma in situ is characterized by which changes?
Cells have broken through the local basement membrane.
Cells have invaded immediate surrounding tissue.
Cells remain localized in the glandular or squamous cells.
Cellular and tissue alterations indicate dysplasia.
Carcinoma in situ (CIS) refers to preinvasive epithelial malignant tumors of
glandular or squamous cell origin. These early stage cancers are localized to
the epithelium and have not broken through the local basement membrane
or invaded the surrounding tissue. Dysplasia refers to changes in mature cell
structure.
Question 3
Which laboratory test is considered adequate for an accurate and
reliable diagnosis of gonococcal urethritis in a symptomatic man?
,Ligase chain reaction (LCR)
Gram-stain technique
Polymerase chain reaction (PCR)
DNA testing
Microscopic evaluation of Gram-stained slides of clinical specimens is
deemed positive for Neisseria gonorrhoeae if gram-negative diplococci with
the typical “kidney bean” morphologic appearance are found inside
polymorphonuclear leukocytes. Such a finding is considered adequate for the
diagnosis of gonococcal urethritis in a symptomatic man. The other options
are not relevant to the diagnosis of this condition.
Question 4
The Papanicolaou (Pap) test is used to screen for which cancer?
Ovarian
Uterine
Cervical
Vaginal
The Pap test, an examination of cervical epithelial scrapings, readily detects
early oncogenic human papillomavirus (HPV)infection. The Pap test is not
used for screening the other cancer sites listed.
Question 5
pts
Causes of hyperkalemia include:
Hyperparathyroidism and malnutrition
,Vomiting and diarrhea
Renal failure and Addison disease
Hyperaldosteronism and Cushing disease
NR507 Advanced Pathophysiology midterm exam question with answers
Hyperkalemia should be investigated when a history of renal disease,
massive trauma, insulin deficiency, Addison disease, use of potassium salt
substitutes, or metabolic acidosis exists. The other options are not known to
be causes of hyperkalemia.
Question 6
pts
What is the major concern regarding the treatment of gonococci infections?
Development of antibiotic resistance
Changes in virulence
Changes in pathogenicity
Mutations into different strains
, Several types of drug-resistant strains have been identified; they are
penicillinase-producing Neisseria gonorrhoeae (PPNG), which is resistant to
penicillin; tetracycline-resistant N. gonorrhoeae (TRNG), which is resistant to
tetracycline; chromosomal control of mechanisms of resistance of N.
gonorrhoeae (CMRNG), which is resistant to penicillin and tetracycline; and
increasingly a fluoroquinolone-resistant N. gonorrhoeae (QRNG). The other
options are not major concerns. NR507 Advanced Pathophysiology midterm
exam question with answers.
Question 7
pts
Hypersensitivity is best defined as a(an):
Disturbance in the immunologic tolerance of self-antigens
Immunologic reaction of one person to the tissue of another person
Altered immunologic response to an antigen that results in disease
Undetectable immune response in the presence of antigens
Hypersensitivity is an altered immunologic response to an antigen that
results in disease or damage to the host. The other options are not accurate
definitions of hypersensitivity.
Question 8
