WGU BioChemistry C785 - Module 1 Questions and Answers with
Verified Solutions | Latest 2026 Update
Q: Nonsense mutation
Answer:
point mutations that change a single base pair in a codon to a stop
codon that terminates translation
Q: frameshift mutation
Answer:
Insertions or deletions of one or more base pairs (if the number of base
pairs is not a multiple of 3) that disrupt the coding of a protein
Q: nucleotide excision repair used to repair this type of mutation
Answer:
, WGU BioChemistry C785 - Module 1 Questions and Answers with
Verified Solutions | Latest 2026 Update
Q: Sources of DNA damage
Answer:
1. UV radiation - bases fuse together to form a thymine dimer that
blocks DNA replication and transcription
2. Ionizing radiation - strands break as well as create reactive O2 species that damage
the bases
3. chemicals - alter the structure of DNA bases
4. Reactive O2 species - damage DNA bases
Q: Nucleotide Excision Repair (NER)
Answer:
DNA damage repair mechanism where several nucleotides,
usually around 30, are removed and replaced.
Useful for deletions, insertions and heliz distortine lesions such as thymine dimers.
(frameshift
mutation)
, WGU BioChemistry C785 - Module 1 Questions and Answers with
Verified Solutions | Latest 2026 Update
Q: Base Excision Repair (BER)
Answer:
DNA damage repair mechanism where a single nucleotide is
replaced,
Q: 1. DNA repair enzymes recognize and remove the damaged base
Answer:
Q: 2. DNA pol adds a new nucleotide
Answer:
Q: 3. ligase seals the remaining nick
Answer:
, WGU BioChemistry C785 - Module 1 Questions and Answers with
Verified Solutions | Latest 2026 Update
Q: mismatch repair or proofreading
Answer:
-repair enzymes correct errors in base pairing
mismatches are not like DNA damage: there is no damaged or modified base present,
just the
wrong one of the four bases. The recognition of mismatches relies on the distortion
of the
double-helical structure.
Q: Thimine Dimers
Answer:
two thymines fuse together
caused by UV radiation
Q: These are repaired by nucelotide excision repair (NER)
Answer:
Verified Solutions | Latest 2026 Update
Q: Nonsense mutation
Answer:
point mutations that change a single base pair in a codon to a stop
codon that terminates translation
Q: frameshift mutation
Answer:
Insertions or deletions of one or more base pairs (if the number of base
pairs is not a multiple of 3) that disrupt the coding of a protein
Q: nucleotide excision repair used to repair this type of mutation
Answer:
, WGU BioChemistry C785 - Module 1 Questions and Answers with
Verified Solutions | Latest 2026 Update
Q: Sources of DNA damage
Answer:
1. UV radiation - bases fuse together to form a thymine dimer that
blocks DNA replication and transcription
2. Ionizing radiation - strands break as well as create reactive O2 species that damage
the bases
3. chemicals - alter the structure of DNA bases
4. Reactive O2 species - damage DNA bases
Q: Nucleotide Excision Repair (NER)
Answer:
DNA damage repair mechanism where several nucleotides,
usually around 30, are removed and replaced.
Useful for deletions, insertions and heliz distortine lesions such as thymine dimers.
(frameshift
mutation)
, WGU BioChemistry C785 - Module 1 Questions and Answers with
Verified Solutions | Latest 2026 Update
Q: Base Excision Repair (BER)
Answer:
DNA damage repair mechanism where a single nucleotide is
replaced,
Q: 1. DNA repair enzymes recognize and remove the damaged base
Answer:
Q: 2. DNA pol adds a new nucleotide
Answer:
Q: 3. ligase seals the remaining nick
Answer:
, WGU BioChemistry C785 - Module 1 Questions and Answers with
Verified Solutions | Latest 2026 Update
Q: mismatch repair or proofreading
Answer:
-repair enzymes correct errors in base pairing
mismatches are not like DNA damage: there is no damaged or modified base present,
just the
wrong one of the four bases. The recognition of mismatches relies on the distortion
of the
double-helical structure.
Q: Thimine Dimers
Answer:
two thymines fuse together
caused by UV radiation
Q: These are repaired by nucelotide excision repair (NER)
Answer:
