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Subject Area NR 565 Advanced Pharmacology Fundamentals final Exam
Description Exam compiled from the shared exam library.
Expected Grade A+
Total Questions 200
Duration 3 hours
Learning Outcomes 1. Demonstrate mastery of core concepts
Accreditation Sourced from the shared exam library.
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,1. A 19-year-old female presents to a clinic with vaginal discharge that has
a foul odor. Microscopic examination reveals Trichomonas vaginalis. The
nurse practitioner is aware that:
Answer: asymptomatic women are diagnosed with trichomoniasis by a
routine Pap smear.
Metronidazole is the recommended first-line treatment for trichomoniasis.
The other options are true statements but do not directly address the nurse
practitioner's awareness regarding treatment.
2. A nurse practitioner is having difficulty administering a bitter-tasting
medication to a 5-year-old child. Which intervention should the nurse
implement to improve the child's acceptance of the medication?
Answer: Offer the child a flavored ice chip or ice pop prior to
administering the drug.
Offering a flavored ice chip or ice pop numbs the taste buds and reduces the
bitter taste, making administration easier. Mixing with a large amount of
food may lead to incomplete ingestion, and telling the child it is candy is
deceptive and unsafe. Crushing tablets is only appropriate if the
formulation allows it.
3. During a party, a guest who is on disulfiram (Antabuse) therapy
consumes half a glass of wine. Which symptoms will the guest quickly
experience? (Select all that apply.)
Answer: Euphoria
Vomiting, flushed skin, and sweating occur when disulfiram is taken with
even small amounts of alcohol. Other symptoms include a throbbing
sensation in the head and neck, hyperventilation, confusion, nausea, vertigo,
and blurred vision. Euphoria, diarrhea, pallor, and hypoventilation do not
occur in this situation.
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,4. A 78-year-old patient is in the recovery room after lengthy hip surgery.
While gradually awakening, the patient requests pain medication. Within
10 minutes after receiving a dose of morphine sulfate, the patient becomes
very lethargic, with shallow respirations at a rate of nine breaths per
minute. Which action should the nurse be prepared to perform?
Answer: Administration of naloxone, an opioid reversal agent
Naloxone, an opioid reversal agent, is used to reverse the effects of acute
opioid overdose and is the drug of choice for reversal of opioid-induced
respiratory depression.
5. A female patient is prescribed warfarin (Coumadin®) in addition to a
heparin infusion. What is the rationale for administering two
anticoagulants concurrently?
Answer: When oral anticoagulants are prescribed, heparin is often used
to initiate therapy until laboratory tests indicate an adequate therapeutic
response.
When oral anticoagulants are prescribed, heparin is often also prescribed to
initiate therapy until laboratory tests indicate an adequate therapeutic
response has been achieved.
6. Which action is considered a standard precaution for medication
administration?
Answer: Discarding all syringes and needles in a puncture-resistant
container
Standard precautions include wearing clean gloves when there is potential
exposure to a patient's blood or other body fluids. Discard all disposable
syringes and needles in an appropriate puncture-resistant container. Never
bend needles or syringes, never recap needles, and never discard syringes
and needles in wastebaskets.
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, 7. A patient has completed 4 weeks of treatment with epoetin alfa. Which
of the following assessment findings would most strongly indicate that
treatment has been effective?
Answer: The patient's hemoglobin level is 11 g/dL.
Epoetin alfa stimulates erythropoiesis, and a hemoglobin level of 11 g/dL
indicates a therapeutic response. While decreased fatigue and increased
reticulocyte count are also positive signs, the most direct and strong
indicator of effectiveness is the hemoglobin level reaching target range.
8. A patient admitted to the critical care unit with bacterial septicemia has
not responded to initial antibiotic therapy. Recent blood cultures indicate
methicillin-resistant Staphylococcus aureus (MRSA). The nurse should
anticipate that this patient will likely require intravenous administration
of which antibiotic?
Answer: vancomycin
Vancomycin is the first-line treatment for MRSA infections, especially in
critically ill patients. The other options are also effective against MRSA but
are typically reserved for vancomycin-resistant strains or specific clinical
scenarios.
9. The nurse assessing a patient receiving intravenous (IV) digitalis
understands that the drug exerts a negative chronotropic effect. Which
assessment finding would the nurse expect as a result of this effect?
Answer: A decreased heart rate
A negative chronotropic effect results in a reduced heart rate, which is one
effect of cardiac glycosides.
10. Solifenacin succinate (Vesicare®) is contraindicated in patients with
which of the following conditions?
Answer: Glaucoma and severe constipation
Solifenacin succinate is contraindicated for patients with glaucoma, certain
gastrointestinal and genitourinary tract problems, severe constipation, and
urinary retention. Diarrhea, dry mouth, and blurred vision are adverse
effects of solifenacin succinate.
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