Practitionersl inl Primaryl Carel IIl Review|l
Wilkesl (Latestl 2026/l 2027l Update)l 100%l
Verifiedl Questionsl &l Answersl |l Gradel A
Q:l Whatl characterizesl Primaryl Raynaudl Phenomenon?
Answer:
Benignl course,l usuallyl affectsl youngl women,l andl isl idiopathic.
Q:l Whatl distinguishesl Secondaryl Raynaudl Phenomenonl froml Primary?
Answer:
Secondaryl canl causel severel complicationsl likel digitall ulcerationl orl gangrene.
Q:l Whatl triggersl episodesl ofl Raynaudl Phenomenon?
Answer:
Coldl orl emotionall stress.
Q:l Whatl isl thel initiall phasel ofl Raynaudl Phenomenonl characterizedl by?
Answer:
Excessivel vasoconstrictionl leadingl tol digitall pallorl andl cyanosis.
Q:l Whatl occursl duringl thel recoveryl phasel ofl Raynaudl Phenomenon?
Answer:
Vasodilationl leadingl tol intensel hyperemial andl rubor.
,Q:l Whatl demographicl isl mostl affectedl byl Primaryl Raynaudl Phenomenon?
Answer:
Womenl agedl 15-30.
Q:l Whatl symptomsl arel associatedl withl Secondaryl Raynaudl Phenomenon?
Answer:
Mayl involvel unilaterall symptomsl andl canl causel digitall pittingl orl gangrene.
Q:l Whatl isl thel typicall clinicall presentationl ofl Polymyalgial Rheumatica?
Answer:
Painl andl stiffnessl inl shoulderl andl pelvicl girdlel areas,l oftenl withl feverl andl malaise.
Q:l Whatl isl thel significancel ofl elevatedl ESRl andl CRPl inl diagnosingl thesel conditions?
Answer:
Theyl indicatel inflammationl butl arel notl absolutel guidesl tol diseasel activity.
Q:l Whatl isl thel recommendedl approachl ifl al patientl withl PMRl doesl notl improvel afterl
steroidl treatment?
Answer:
Thel diagnosisl shouldl bel revisitedl ifl nol dramaticl improvementl isl seenl withinl 72l hours.
Q:l Whatl arel commonl rheumaticl diseasesl mentioned?
Answer:
,Systemicl sclerosis,l neurovascularl compression,l carpall tunnell syndrome,l thoracicl outletl
obstruction,l vibrationl injury.
Q:l Whatl isl thel clinicall presentationl ofl Raynaud'sl phenomenonl (RP)?
Answer:
Paroxysmall bilaterall digitall pallorl andl cyanosisl followedl byl rubor,l typicallyl
asymptomaticl betweenl attacks.
Q:l Whatl colorl changesl occurl inl fingers/toesl duringl RPl episodes?
Answer:
Whitel (ischemia)l ->l bluel (cyanosis)l ->l redl (rubor).
Q:l Whatl initiall diagnosticsl arel usedl forl secondaryl RP?
Answer:
Nailfoldl capillaryl abnormalitiesl visualizedl withl anl ophthalmoscope,l ANAl andl
autoimmunel panels,l TSHl tol rulel outl hypothyroidism.
Q:l Whatl arel thel managementl strategiesl forl Raynaud'sl phenomenon?
Answer:
Keepingl warm,l wearingl gloves,l protectingl hands,l usingl softeningl lotion,l stoppingl
smoking,l andl consideringl sympathectomyl forl severel cases.
Q:l Whatl arel thel commonl drugl classificationsl forl managingl Raynaud'sl phenomenon?
Answer:
CCBs,l angiotensinl IIl receptorl blockers,l topicall nitrates,l phosphodiesterasel inhibitors,l andl
SSRIs.
, Q:l Whatl isl thel prevalencel ofl rheumatoidl arthritisl (RA)?
Answer:
1%,l morel commonl inl womenl thanl menl (3:1).
Q:l Whatl isl thel peakl onsetl agel forl RAl inl womenl andl men?
Answer:
4thl orl 5thl decadel forl womenl andl 6th-8thl decadesl forl men.
Q:l Whatl arel thel mainl immunel componentsl involvedl inl RAl pathophysiology?
Answer:
Tl cells,l Bl cells,l macrophages,l andl pro-inflammatoryl cytokinesl likel TNF-αl andl IL-6.
Q:l Whatl arel commonl clinicall presentationsl ofl RA?
Answer:
Insidiousl onset,l symmetricall polyarthritis,l morningl stiffnessl >l 30l min,l fatigue,l low-gradel
fever.
Q:l Whatl jointsl arel commonlyl affectedl byl rheumatoidl arthritis?
Answer:
Smalll jointsl ofl thel handsl (MCP,l PIP)l andl feetl (MTP).
Q:l Whatl arel somel extra-articularl featuresl ofl RA?
Answer:
Rheumatoidl nodules,l interstitiall lungl disease,l vasculitis.