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According to the WHO criteria, what is the diagnosis of
osteoporosis based on the measurement of bone density? -
ANSWER-2.5 SD or more below the young adult peak bone
density
What is the gold standard technique for measuring bone
density? - ANSWER-DXA
Cancellous bone is also know as? - ANSWER-Trabecular Bone
What is the anatomical landmark on the proximal femur that
gives the best visual indication of the degree of rotation of the
proximal femur? - ANSWER-Lesser Trochanter
Which lumbar vertebra is described as having a characteristic
shape of an X or and H on a DXA PA spine scan? - ANSWER-L4
Is Forteo a bisphosphonate? - ANSWER-NO
Quantitative Computated Tomography (QCT) - ANSWER--
measurements are volumetric
,-trabecular bone can be isolated from cortical bone
-accuracy may be affected by marrow fat
Peripheral BMD measurements are advocated for
_____________? - ANSWER-Screening
What is the most important clinical consequence of
osteoporosis? - ANSWER-Fracture
What is the name of the tool that integrates clinical information
in a quantitative manner to predict a 10-year probability of
major osteoporotic fracture for both men and women? -
ANSWER-FRAX
What is the major source of precision error in clinical practice?
- ANSWER-Technologist
What is the percentage of trabecular bone in the skeleton? -
ANSWER-20 %
The forearm is not used to monitor the effects of therapy for
osteoporosis because....... - ANSWER-rate of change in BMD is
too slow
What site is mostly composed of cortical bone? - ANSWER-
Proximal forearm
,What are the advantages of QUS over x-ray methodologies for
BMD measurement? - ANSWER--ultrasound is comparatively
inexpensive
-patients are not subjected to ionizing radiation
-ultrasound exams are quick to perform
What is the name of the isotope that was used in SPA? -
ANSWER-Iodine-125
What is the texture index that evaluates the pixel gray-level
variations in lumber spine DXA images? - ANSWER-TBS
(Trabecular Bone Score)
When does type 2 primary osteoporosis generally occur? -
ANSWER-after age 70
What technique used images of the hand and an aluminum
wedge? - ANSWER-RA (Radiograhic Absorptiometry)
New bone is formed by the ___________? - ANSWER-
osteoblasts
Cancellous bone is also known as _______________? -
ANSWER-Trabecular bone
How would you start labeling the vertebral bodies on a PA
lumbar scan? - ANSWER-Start at L4 and count/label up
, With changes in rotation of the femoral neck, what happens? -
ANSWER-Increases the BMD
If daily QC fails, what should be your first step of action? -
ANSWER--repeat the scan
-if scan fails again, then call for help
Although the technology is similar with all of the DXA units, the
BMD results are different because.......... - ANSWER--different
calibration standards
-algorithms to calculate BMD
-differences in the ROI
-different databases
The primary mechanism of action of antiresorptive therapies is
the direct interaction with the __________________ - ANSWER-
osteoclasts
Which site is preferred for determination of fracture prediction?
- ANSWER-proximal femur
What skeletal sites are predominantly cortical bone? -
ANSWER--total body