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AANP Practice Questions with correct answers graded a+ for assured excel!!

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AANP Practice Questions with correct answers graded a+ for assured excel!!

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APEA Pre-Predictor & NP Board

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AANP Practice Questions with correct
answers graded a+ for 2026-2027
assured excel!!
Question 201

A patient presents with episodic flushing, diarrhea, and wheezing. What is the most likely
diagnosis?

A. Addison disease

B. Carcinoid syndrome

C. IBS

D. Crohn disease

Correct Answer: B. Carcinoid syndrome

Rationale:
Carcinoid tumors release serotonin causing flushing, diarrhea, and bronchospasm.

Question 202

Which test is most specific for diagnosing acute pancreatitis?

A. ALT

B. Serum amylase

C. Serum lipase

D. Alkaline phosphatase

Correct Answer: C. Serum lipase

Rationale:
Lipase is more specific and remains elevated longer than amylase.

Question 203

,Which condition is associated with “pan-systolic murmur at left lower sternal border”?

A. Mitral regurgitation

B. Tricuspid regurgitation

C. Aortic stenosis

D. Pulmonic stenosis

Correct Answer: B. Tricuspid regurgitation

Rationale:
Tricuspid regurgitation is heard best at the left lower sternal border.

Question 204

Which condition is associated with “Fried egg appearance” on imaging?

A. Hodgkin lymphoma

B. Tuberculosis

C. Sarcoidosis

D. Pneumonia

Correct Answer: A. Hodgkin lymphoma

Rationale:
Reed-Sternberg cells give classic appearance in Hodgkin lymphoma.

Question 205

Which condition is associated with “positive Nikolsky sign”?

A. Psoriasis

B. Pemphigus vulgaris

C. Eczema

D. Tinea

Correct Answer: B. Pemphigus vulgaris

, Rationale:
Skin sloughing with pressure is seen in pemphigus vulgaris.

Question 206

Which electrolyte imbalance is most associated with vomiting and metabolic alkalosis?

A. Hyperkalemia

B. Hypokalemia

C. Hypercalcemia

D. Hypermagnesemia

Correct Answer: B. Hypokalemia

Rationale:
Vomiting leads to loss of gastric acid and potassium.

Question 207

Which condition is associated with “anchor-shaped cells” on smear?

A. Iron deficiency anemia

B. Sickle cell disease

C. Thalassemia

D. Aplastic anemia

Correct Answer: B. Sickle cell disease

Rationale:
Sickled erythrocytes appear crescent or anchor-shaped.

Question 208

Which condition is associated with “hyperresonance on percussion and absent breath sounds”?

A. Pneumonia

B. Pneumothorax

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