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Pharmacology Final Exam / Review Bank

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Pharmacology Final Exam / Review Bank

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Pharmacology Final Exam / Review Bank



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Advanced Clinical Pharmacology


Which drug requires a dietary restriction for foods containing tyramine?
A. nortriptyline (TCA)
B. tranylcypromine (MAOI)
C. venlafaxine (SNRI)
D. fluoxetine (SSRI)
E. methamphetamine
B. tranylcypromine (MAOI)
the site of action of diazepam (Valium) to relieve anxiety is the
A. spinal cord
B. limbic system
C. reticular formation
D. basal ganglia
E. cerebellum
B. limbic system
The antianxiety effect of buspirone (BuSpar) is associated with
A. stimulation of DA receptors
B. stimulation of serotonin receptors
C. blockage of serotonin receptors
D. blockade of dopamine receptors
E. blockage of GABA receptors
C. blockage of serotonin receptors
Flumazenil (Romazicon) is used to reverse the depressant effects of
A. clozapine
B. alprazolam (benzodiazepine)
C. haloperidol
D. chlorpromazine
E. thiothixene
B. alprazolam (benzodiazepine
What are the main areas at which benzodiazepines exert their effects?
A. limbic system
B. cerebral cortex

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C. reticular formation
D. spinal cord
E. all of these
E. all of these
Symptoms of Parkinson's disease would be increased by
A. excess levels of acetylcholine
B. treatment with some antipsychotic drugs
C. decreased levels of dopamine
D. drug administration after a high-protein meal
E. all of these
E. all of these
The drug classified as a dopamine receptor agonist is
A. amantadine
B. benztropine
C. ropinirole
D. entacapone (COMT)
E. carbidopa
C. ropinirole
Select the drugs that increase the duration of action of DA and/or the amount
of levodopa that enters the brain.
A. carbidopa
B. tolcapone
C. selegiline
D. rasagiline
E. all of these
E. all of these
In Parkinson's disease, slowed movements are defined as
A. rigidity
B. bradykinesia
C. tremor
D. dystonia
E. postural instability
B. bradykinesia

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Sinemet is the trade name of a drug combination that contains levodopa and
A. carbidopa and entacapone
B. entacapone
C. carbidopa
D. selegiline
E. amantadine
C. carbidopa
The COMT inhibitor that has been associated with causing liver toxicity is
A. ropinirole
B. entacapone
C. pramipexole
D. tolcapone
E. benztropine
D. tolcapone
Select the symptoms of Parkinson's disease
A. muscular rigidity
B. increased sweating
C. salivary drooling
D. movement disturbances
E. all of these
E. all of these
Which of the following drugs would be used to decrease the actions of ACH?
A. amantadine
B. levodopa
C. bromocriptine
D. procyclidine
E. carbidopa
D. procyclidine
Select the mechanisms by which levodopa works.
A. crosses blood-brain barrier by an amino acid transporter
B. converted to dopamine in the substantia nigra neurons
C. increases level of dopamine in the brain
D. peripheral metabolism to DA inhibited by carbidopa
E. all of these

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