ALL THE COMSAE QUESTIONS AND
ANSWERS
drug-for-UC/Crohns---ans-✔✔sulfasalazine
pulmonary-effects-of-CF---ans-✔✔chronic-bronchitis-an-dbronchiectasis
osteoporosis-affects-what-parts-of-bone?---ans-✔✔(spongy-and-)-trabecular-bone-mass-
loss
imipramine---ans-✔✔TCA
SE:-Tri-Cs
convulsions
coma
cardiotox
antichol-effects--confusion-in-elderly;-(acute-glaucoma-and-orthostatic-hypotension--block-
alpha1)
viscerosomatic---ans-✔✔visceral-disease--->-somatic-finding
loratidine-vs-ranitidine---ans-✔✔loratidine:-2nd-gen-H1-blocker,-doesnt-cross-BBB--->-
less-sedating
ranitidine:-H2-receptor-antagonist-(like-cimetidine)
cells-w-RBCs-inside---ans-✔✔entaemoba-histolytica
which-type-of-pneumothorax-causes-tracheal-deviation-to-the-contra-side?---ans-
✔✔tension
intracerebral-hemorrhage-adjacent-to-a-lesion-that-contains-a-tangle-of-numerous-
tortuous-vessels---ans-✔✔AVM-arteriovenous-malformation
cavernous-hemangioma---ans-✔✔benign-tumor-of-liver,-A/W-VHL
anti-HepB-surface-antibody-is-only-present-in-what-pop---ans-✔✔recovered-or-immunized
,not-in-chronic-or
proctalgia-fugax---ans-✔✔levator-ani-syndrome
fasciculus-is-UMN-or-LMN-lesion?---ans-✔✔LMN
ectopic-gastric-tissue---ans-✔✔meckels-diverticulum
can-also-have-ectopic-pancreatic-tissue
remnant-of-vitelline-duct
antibodies-in-hashimotos-attacks---ans-✔✔thyroid-peroxidase-or-antithyroglobulin
enlarged-non-tender-thyroid
2-factors-that-influence-starling-curve---ans-✔✔x-axis--preload-(EDV)
y-axis--stroke-volume-or-CO
treatment-for-fibromyalgia---ans-✔✔TCA,-SNRIs-anticonvulsants
what-blocks-NE-reuptake?---ans-✔✔TCA-or-SNRIs
possible-complication-of-pagets-bone-disease---ans-✔✔osteocarcoma
what-does-Hct-tell-you?---ans-✔✔ratio-of-volume-of-RBCs-compared-to-total-blood-volume
probenecid---ans-✔✔inhibits-reabsoprtion-of-uric-acid-in-PCT
--also-inhibits-secretion-of-PCN
--can-ppt-uric-acid-calculi
2-causes-of-SCID---ans-✔✔ADA-deficiency
(adenosine-deaminase-required-for-degradation-of-adenosim-and-deoxyadenosine
--in-ADA-deficiency,-high-levels-of-dATP--->-toxicity-in-lymphocytes--->-SCID
hypoplastic-thymus
lithiums-effects-on-urination---ans-✔✔inhibits-vasopression/ADH--->-increased-urinary-
frequency
infertility-drug-that-can-result-in-multiple-fetuses---ans-✔✔clomiphene-(clones--multiple-
babies)
antagonist-at-estrogen-R-in-hypothalamus-(thus-inhibits-normal-negative-feedback)
,upregulates-LH-and-FSH-release-from-pituitary--->-ovulation
used-to-treat-PCOS-but-can-cause-ovarian-enlargement,-multiple-fetuses
AFP-levels-in-down-syndrome---ans-✔✔low
GI-malformation-A/W-down-syndrome---ans-✔✔Hirschprungs--congenital-aganglionic-
megacolon
defective-relaxation-and-peristalsis-of-rectum-and-distal-sigmoid-colon
failure-to-pass-meconium,-empty-rectal-vault,-megacolon
myasthenia-gravis-associations---ans-✔✔thymoma,-thymic-hyperplasia
ptosis,-diplopia,-can-affect-chewing,-swallowing,-speaking,-shoulders,-respiration
tx-for-tinea---ans-✔✔azoles
beta-blockers-for-asthma---ans-✔✔none--even-beta-1s-can-be-nonselective-at-higher-
doses
what-kind-of-teratogenic-effects-are-seen-w-ACE/ARBs---ans-✔✔fetal-renal-agenesis
stones-bones-groans-moans-psych-overtones---ans-✔✔high-Ca-or-PTH
PTH-is-made-by-what-cells?---ans-✔✔chief-cells-of-parathyroid-gland
PTH-inhibits-reabsorption-of-phosphate-where?-increases-calcium-resorption-where?---
ans-✔✔PO4--proximal-tubule
ca--DCT
anterior-innominate-rotation-means-tight-hip-flexors-or-extensors?---ans-✔✔extensor--
hamstrings
thoracic-CS---ans-✔✔E-SaRa
most-common-cause-of-cellultis---ans-✔✔staph-aureus,-strep-pyogenes
FPR--direct-or-indirect?-active-or-passive?---ans-✔✔indirect--place-them-in-position-of-
diagnosis
passive
cant-treat-kid-w-tetracycline-so-what-do-you-give?---ans-✔✔amoxicillin
which-Heps-are-there-currently-vaccines-for?---ans-✔✔A-and-B-(and-so-by-virtue,-also-D)
, why-does-Hep-D-need-Hep-B?---ans-✔✔Hep-D-utilizes-the-HBV-surface-antigen-as-its-
envelope?
most-common-hepatitis-A/W-IVDA-in-the-US---ans-✔✔hep-c
roseola---ans-✔✔4-day-high-fever
then-rash-on-the-trunk-(spares-face)
affects-babies-up-to-2-years
HHV6--affects-CD4-helper-cells-and-kills-them-off
erythema-infectiosum---ans-✔✔slapped-cheek
parvovirus-B19
nonspecific-fever/prodrome-then-slapp-cheek-rash-5-days-later,-then-rash-appears-on-
arms-and-spreads-to-trunk/legs
rash-can-worsen-w-fever-and-sun-exposure
TORCH-infxn-so-baby-in-womb-that-is-exposed-can-lead-to-hydrops-fetalis
most-common-STD---ans-✔✔chlamydia
sxs-similar-to-STI-plus-discharge
will-have-high-neutrophil-count
dimorphic--butterflies---ans-✔✔candida,-histo,-cocci,-paracocci,-blasto,-sporothrix,
butterflies-huge-pair-of-cocc-catching-stamp
hip-restricted-in-internal-rotation
dx?---ans-✔✔innom-outflare
immune-complex-in-glomerular-mesangium-2-days-after-URI
berger-or-PSGN?---ans-✔✔berger
PSGN-is-2-wks-post-URI
kidney-ureter-viscerosomatic-innervation---ans-✔✔T10-11
ANSWERS
drug-for-UC/Crohns---ans-✔✔sulfasalazine
pulmonary-effects-of-CF---ans-✔✔chronic-bronchitis-an-dbronchiectasis
osteoporosis-affects-what-parts-of-bone?---ans-✔✔(spongy-and-)-trabecular-bone-mass-
loss
imipramine---ans-✔✔TCA
SE:-Tri-Cs
convulsions
coma
cardiotox
antichol-effects--confusion-in-elderly;-(acute-glaucoma-and-orthostatic-hypotension--block-
alpha1)
viscerosomatic---ans-✔✔visceral-disease--->-somatic-finding
loratidine-vs-ranitidine---ans-✔✔loratidine:-2nd-gen-H1-blocker,-doesnt-cross-BBB--->-
less-sedating
ranitidine:-H2-receptor-antagonist-(like-cimetidine)
cells-w-RBCs-inside---ans-✔✔entaemoba-histolytica
which-type-of-pneumothorax-causes-tracheal-deviation-to-the-contra-side?---ans-
✔✔tension
intracerebral-hemorrhage-adjacent-to-a-lesion-that-contains-a-tangle-of-numerous-
tortuous-vessels---ans-✔✔AVM-arteriovenous-malformation
cavernous-hemangioma---ans-✔✔benign-tumor-of-liver,-A/W-VHL
anti-HepB-surface-antibody-is-only-present-in-what-pop---ans-✔✔recovered-or-immunized
,not-in-chronic-or
proctalgia-fugax---ans-✔✔levator-ani-syndrome
fasciculus-is-UMN-or-LMN-lesion?---ans-✔✔LMN
ectopic-gastric-tissue---ans-✔✔meckels-diverticulum
can-also-have-ectopic-pancreatic-tissue
remnant-of-vitelline-duct
antibodies-in-hashimotos-attacks---ans-✔✔thyroid-peroxidase-or-antithyroglobulin
enlarged-non-tender-thyroid
2-factors-that-influence-starling-curve---ans-✔✔x-axis--preload-(EDV)
y-axis--stroke-volume-or-CO
treatment-for-fibromyalgia---ans-✔✔TCA,-SNRIs-anticonvulsants
what-blocks-NE-reuptake?---ans-✔✔TCA-or-SNRIs
possible-complication-of-pagets-bone-disease---ans-✔✔osteocarcoma
what-does-Hct-tell-you?---ans-✔✔ratio-of-volume-of-RBCs-compared-to-total-blood-volume
probenecid---ans-✔✔inhibits-reabsoprtion-of-uric-acid-in-PCT
--also-inhibits-secretion-of-PCN
--can-ppt-uric-acid-calculi
2-causes-of-SCID---ans-✔✔ADA-deficiency
(adenosine-deaminase-required-for-degradation-of-adenosim-and-deoxyadenosine
--in-ADA-deficiency,-high-levels-of-dATP--->-toxicity-in-lymphocytes--->-SCID
hypoplastic-thymus
lithiums-effects-on-urination---ans-✔✔inhibits-vasopression/ADH--->-increased-urinary-
frequency
infertility-drug-that-can-result-in-multiple-fetuses---ans-✔✔clomiphene-(clones--multiple-
babies)
antagonist-at-estrogen-R-in-hypothalamus-(thus-inhibits-normal-negative-feedback)
,upregulates-LH-and-FSH-release-from-pituitary--->-ovulation
used-to-treat-PCOS-but-can-cause-ovarian-enlargement,-multiple-fetuses
AFP-levels-in-down-syndrome---ans-✔✔low
GI-malformation-A/W-down-syndrome---ans-✔✔Hirschprungs--congenital-aganglionic-
megacolon
defective-relaxation-and-peristalsis-of-rectum-and-distal-sigmoid-colon
failure-to-pass-meconium,-empty-rectal-vault,-megacolon
myasthenia-gravis-associations---ans-✔✔thymoma,-thymic-hyperplasia
ptosis,-diplopia,-can-affect-chewing,-swallowing,-speaking,-shoulders,-respiration
tx-for-tinea---ans-✔✔azoles
beta-blockers-for-asthma---ans-✔✔none--even-beta-1s-can-be-nonselective-at-higher-
doses
what-kind-of-teratogenic-effects-are-seen-w-ACE/ARBs---ans-✔✔fetal-renal-agenesis
stones-bones-groans-moans-psych-overtones---ans-✔✔high-Ca-or-PTH
PTH-is-made-by-what-cells?---ans-✔✔chief-cells-of-parathyroid-gland
PTH-inhibits-reabsorption-of-phosphate-where?-increases-calcium-resorption-where?---
ans-✔✔PO4--proximal-tubule
ca--DCT
anterior-innominate-rotation-means-tight-hip-flexors-or-extensors?---ans-✔✔extensor--
hamstrings
thoracic-CS---ans-✔✔E-SaRa
most-common-cause-of-cellultis---ans-✔✔staph-aureus,-strep-pyogenes
FPR--direct-or-indirect?-active-or-passive?---ans-✔✔indirect--place-them-in-position-of-
diagnosis
passive
cant-treat-kid-w-tetracycline-so-what-do-you-give?---ans-✔✔amoxicillin
which-Heps-are-there-currently-vaccines-for?---ans-✔✔A-and-B-(and-so-by-virtue,-also-D)
, why-does-Hep-D-need-Hep-B?---ans-✔✔Hep-D-utilizes-the-HBV-surface-antigen-as-its-
envelope?
most-common-hepatitis-A/W-IVDA-in-the-US---ans-✔✔hep-c
roseola---ans-✔✔4-day-high-fever
then-rash-on-the-trunk-(spares-face)
affects-babies-up-to-2-years
HHV6--affects-CD4-helper-cells-and-kills-them-off
erythema-infectiosum---ans-✔✔slapped-cheek
parvovirus-B19
nonspecific-fever/prodrome-then-slapp-cheek-rash-5-days-later,-then-rash-appears-on-
arms-and-spreads-to-trunk/legs
rash-can-worsen-w-fever-and-sun-exposure
TORCH-infxn-so-baby-in-womb-that-is-exposed-can-lead-to-hydrops-fetalis
most-common-STD---ans-✔✔chlamydia
sxs-similar-to-STI-plus-discharge
will-have-high-neutrophil-count
dimorphic--butterflies---ans-✔✔candida,-histo,-cocci,-paracocci,-blasto,-sporothrix,
butterflies-huge-pair-of-cocc-catching-stamp
hip-restricted-in-internal-rotation
dx?---ans-✔✔innom-outflare
immune-complex-in-glomerular-mesangium-2-days-after-URI
berger-or-PSGN?---ans-✔✔berger
PSGN-is-2-wks-post-URI
kidney-ureter-viscerosomatic-innervation---ans-✔✔T10-11
