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innate immunity Answer: Innate Immunity: Non-specific
- 2 categories:
o First defense system: surface (external) defenses
-- Skin, mucus membranes, secretions, normal flora
--Mechanical barriers
--Chemical barriers
o Second defense system: internal defenses
--Cellular components: WBC’s
--Humoral components: molecules in serum/plasma
--Inflammation response
--Phagocytosis
CD markers (cluster of differentiation) Answer: - All white cells are CD45
Adaptive immunity is the _________ line of defense and is ____________. Answer: Adaptive
immunity is the third line of defense and is specific.
Adaptive immunity Answer: o Third line defense: adaptive
§ Specific immune responses
adaptive immunity third line of defense consists of what? Answer: Cellular reactions or
components specific for an antigen
humoral components in the blood specific for an antigen
adaptive immunity characteristics Answer: -specific
-antigen dependent
-predominate in middle and late stage of infection
-delayed response
-has memory
-highly diverse specificity
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, -response due to recognition of a specific antigen
-response to repeat infection is more rapid than 1st response
The cellular components of the adaptive immune system are ________ while the humoral
components are __________? Answer: The cellular components of the adaptive immune
system are T and B lymphocytes while the humoral components are antibodies
-If you don’t have thymus, t cells, or b cells you cannot fight infections well
Adaptive immunity:
B cells Answer: B cells:
• 10-15% of circulating lymphocyte
Differentiation in the bone marrow
Antigen presenting cell
Precursor of plasma cell
Primary role is to produce immunoglobulin
Adaptive immunity:
T cells Answer: T cells:
60-80% of circulating lymphocyte
Differentiation in the thymus
3 subsets:
helper,
cytotoxic, and
regulator
Produce cytokines that stimulate the immune system•
Assist in killing tumor cells or infection target cells
Lymphocytes and the adaptive immune system Answer: Lymphocytes are the key
mediators of the adaptive immune system.
humoral immunity:
responding lymphocytes?
functions? Answer: humoral immunity:
responding lymphocytes:
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