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IPSC EXAM Questions And CORRECT Answers

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IPSC EXAM Questions And CORRECT Answers What are induced pluripotent stem cells (iPSCs), and what are their main characteristics? - CORRECT ANSWERS * Adult somatic cells reprogrammed into stem-cell-like cells * Pluripotent → can form all 3 germ layers (ectoderm, mesoderm, endoderm) * Similar to embryonic stem cells * Avoid major ethical concerns * Can be patient-specific → lower risk of immune rejection How are iPSCs created? - CORRECT ANSWERS * Oct4 * Sox2 * Klf4 * c-Myc

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IPSC EXAM Questions And CORRECT Answers
What are induced pluripotent stem cells (iPSCs), and what are their main characteristics? - CORRECT
ANSWERS * Adult somatic cells reprogrammed into stem-cell-like cells

* Pluripotent → can form all 3 germ layers (ectoderm, mesoderm, endoderm)

* Similar to embryonic stem cells

* Avoid major ethical concerns

* Can be patient-specific → lower risk of immune rejection



How are iPSCs created? - CORRECT ANSWERS By introducing the Yamanaka factors:



* Oct4

* Sox2

* Klf4

* c-Myc



using viral or non-viral vectors.



Memory trick: OSKM

(Oct4, Sox2, Klf4, c-Myc)



What are the major applications of iPSCs? - CORRECT ANSWERS * Disease modeling

* Drug testing and development

* Regenerative medicine (tissue repair/replacement)

* Genetic and developmental studies



What are the advantages and disadvantages of iPSCs? - CORRECT ANSWERS Advantages



* No embryo destruction

* Patient-specific cells

* Pluripotent

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