CCTC TRANSPLANT PHARMACOLOGY
PRACTICE TEST 2026 TESTED QUESTIONS
AND CORRECT ANSWERS
◉ In the adolescent population, the MOST common cause of graft
loss after the first year of transplantation is
a. nonadherence
b. viral infection
c. bacterial infection
d. recurrent disease
Answer: a. nonadherence
◉ A 55-year-old female four years post-liver transplant for primary
biliary cirrhosis is on prednisone and cyclosporine. She presents to
the clinic with right leg and knee pain with an altered gait for the
last three months. The transplant coordinator should suspect
a. arthritis
b. osteomyelitis
c. CMV infection
d. aseptic necrosis
Answer: d. aseptic necrosis
,◉ After a patient's evaluation for kidney transplant, he called the
transplant center to review the testing. The coordinator should be
MOST concerned about which of the following statements by the
patient?
a. I'm worried about the cost of medications.
b. How long do i have to take antirejection medications?
c. Now that my testing is complete, I can be placed on the list.
d. My wife and I are getting divorced, and I am on her insurance
plan.
Answer: d. My wife and I are getting divorced, and I am on her
insurance plan.
◉ Which of the following is the MOST important risk factor for Post-
Transplant Lymphoproliferative Disease (PTLD)?
a. concomitant CMV and EBV disease
b. induction with interleukin-2 receptor antagonist
c. high EBV polymer chain reaction at time of transplant
d. transplant of an EBV seropositive organ into a seronegative
recipient
Answer: d. transplant of an EBV seropositive organ into a
seronegative recipient
◉ Which of the following is a potential contraindication to living
kidney donation?
,A. glomerular filtration rate of greater than 80 mL/min
B. history of recurrent nephrolithiasis
C. donor age of 18 or older
D. the donor being unrelated to the recipient
Answer: B. history of recurrent nephrolithiasis
◉ A potential candidate evaluation includes histocompatibility
testing, Class I and II HLA antigen typing, and HLA antibody testing.
When listing the candidate for transplant in UNOS, the coordinator
will anticipate identifying the Class I and II HLA antigens and
A. all unacceptable HLA antigens identified.
B. all unacceptable HLA antigens with MFI > 10000.
C. only donor specific HLA antibodies.
D. only unacceptable HLA antigens identified by the program.
Answer: D. only unacceptable HLA antigens identified by the
program.
◉ Which of the following is required from a recipient for a final
crossmatch?
A. serum
, B. whole blood
C. splenic tissue
D. lymph nodes
Answer: A. serum
◉ When determining the suitability of a potential living donor,
which of the following findings will prevent kidney donation?
A. no medical insurance
B. horseshoe kidney
C. hyperlipidemia
D. diabetes
Answer: D. diabetes
◉ A transplant coordinator notifies a potential kidney transplant
candidate that he can be added to the UNOS wait list, but will need
HLA testing. The potential candidate reports receiving a blood
transfusion 7 days ago. The coordinator should inform the potential
candidate that
A. he must wait one month for HLA testing.
B. he can be HLA tested and added to the list immediately.
C. his PRA will now be too high and patient cannot be listed.
PRACTICE TEST 2026 TESTED QUESTIONS
AND CORRECT ANSWERS
◉ In the adolescent population, the MOST common cause of graft
loss after the first year of transplantation is
a. nonadherence
b. viral infection
c. bacterial infection
d. recurrent disease
Answer: a. nonadherence
◉ A 55-year-old female four years post-liver transplant for primary
biliary cirrhosis is on prednisone and cyclosporine. She presents to
the clinic with right leg and knee pain with an altered gait for the
last three months. The transplant coordinator should suspect
a. arthritis
b. osteomyelitis
c. CMV infection
d. aseptic necrosis
Answer: d. aseptic necrosis
,◉ After a patient's evaluation for kidney transplant, he called the
transplant center to review the testing. The coordinator should be
MOST concerned about which of the following statements by the
patient?
a. I'm worried about the cost of medications.
b. How long do i have to take antirejection medications?
c. Now that my testing is complete, I can be placed on the list.
d. My wife and I are getting divorced, and I am on her insurance
plan.
Answer: d. My wife and I are getting divorced, and I am on her
insurance plan.
◉ Which of the following is the MOST important risk factor for Post-
Transplant Lymphoproliferative Disease (PTLD)?
a. concomitant CMV and EBV disease
b. induction with interleukin-2 receptor antagonist
c. high EBV polymer chain reaction at time of transplant
d. transplant of an EBV seropositive organ into a seronegative
recipient
Answer: d. transplant of an EBV seropositive organ into a
seronegative recipient
◉ Which of the following is a potential contraindication to living
kidney donation?
,A. glomerular filtration rate of greater than 80 mL/min
B. history of recurrent nephrolithiasis
C. donor age of 18 or older
D. the donor being unrelated to the recipient
Answer: B. history of recurrent nephrolithiasis
◉ A potential candidate evaluation includes histocompatibility
testing, Class I and II HLA antigen typing, and HLA antibody testing.
When listing the candidate for transplant in UNOS, the coordinator
will anticipate identifying the Class I and II HLA antigens and
A. all unacceptable HLA antigens identified.
B. all unacceptable HLA antigens with MFI > 10000.
C. only donor specific HLA antibodies.
D. only unacceptable HLA antigens identified by the program.
Answer: D. only unacceptable HLA antigens identified by the
program.
◉ Which of the following is required from a recipient for a final
crossmatch?
A. serum
, B. whole blood
C. splenic tissue
D. lymph nodes
Answer: A. serum
◉ When determining the suitability of a potential living donor,
which of the following findings will prevent kidney donation?
A. no medical insurance
B. horseshoe kidney
C. hyperlipidemia
D. diabetes
Answer: D. diabetes
◉ A transplant coordinator notifies a potential kidney transplant
candidate that he can be added to the UNOS wait list, but will need
HLA testing. The potential candidate reports receiving a blood
transfusion 7 days ago. The coordinator should inform the potential
candidate that
A. he must wait one month for HLA testing.
B. he can be HLA tested and added to the list immediately.
C. his PRA will now be too high and patient cannot be listed.
