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, Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What is t
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he expected effect for this prescription?
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A. Curative effect on symptoms ma ma ma
B. Systemic effect on symptoms ma ma ma
C. Local effect on symptoms ma ma ma
D. Parenteral effect on symptoms ma ma ma
ANS: B m a
Rationale: Drugs that produce systemic effects are taken into the body, circulated through
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the bloodstream to their sites of action in various body tissues, and eventually eliminated f
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rom the body. Curative agents are given to cure a disease process. In this case, paroxetine
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hydrochloride will control the symptoms but not cure the disorder. Drugs with local effects,
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such as sunscreen and local anesthetics, act mainly at the site of application. Paroxetine h
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ydrochloride is not administered parenterally. Parenteral agents are administered subcutane
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ously, intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1 ma ma
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapie
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s TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
m a NOT: Multiple Choice ma ma m a ma
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
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alDlyEm
SoBdOifOieSd.TW
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medication?
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A. Synthetic drug ma
B. Semisynthetic drug ma
C. Biotechnology drug ma
D. Prototype drug ma
ANS: B m a
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances t
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hat have been chemically modified. Synthetic drugs are more standardized in their chemical
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characteristics, more consistent in their effects, and less likely to produce allergic reaction
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s. Biotechnology drugs involve manipulating DNA and RNA and recombining genes into
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hybrid molecules that can be inserted into living organisms. Prototype drugs are the first d
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rug of a particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 ma ma ma
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapie
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s TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
m a NOT: Multiple Choice ma ma m a ma
3. Which classification applies to morphine?
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A. Central nervous system depressant ma ma ma
B. Central nervous system stimulant ma ma ma
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