ATI | PN Pharmacology
OBJECTIVE ASSESSMENT - EXAM
ATI PN Pharmacology Proctor
Exam | 2026/2027 NGN-Style
Questions & Case Studies |
Pharmacology ATI (PDF)
2026/2027
PN Proctored Assessment | NGN-Aligned
75 100%
QUESTIONS VERIFIED ANSWERS EDITION
TOPICS COVERED
Drug Classifications & Mechanisms of Action Neurological & Psychiatric Medications
Cardiovascular Pharmacology Endocrine & Metabolic Agents
Respiratory Medications Anti-Infective & Immune Therapy
COVER PAGE - 1
, SECTION 1 | Pharmacology Basics | Q1-Q75 | ATI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Q
Q1 Question 1 of 75
A 68-year-old client is prescribed digoxin 0.25 mg orally daily. The nurse reviews the
client's medication history and notes the client also takes furosemide 40 mg daily.
The nurse recognizes that concurrent use of these medications increases the risk of
which adverse effect?
A. Hyperkalemia
B. Digoxin toxicity
C. Hypotension
D. Bradycardia
Correct Answer: B
Rationale:
Furosemide is a loop diuretic that causes potassium depletion. Hypokalemia increases the risk of
digoxin toxicity because low potassium levels enhance digoxin binding to cardiac tissue. The nurse
should monitor potassium levels closely.
Q2 Question 2 of 75
A nurse is preparing to administer a medication via the intramuscular route to a
45-year-old client. The nurse selects the ventrogluteal site and plans to insert the
needle at which angle?
A. 15 degrees
B. 45 degrees
C. 90 degrees
D. 30 degrees
Correct Answer: C
Rationale:
The ventrogluteal site is the preferred intramuscular injection site for adults because it is free of major
nerves and blood vessels. The needle should be inserted at a 90-degree angle to reach the muscle
tissue.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 2 of 4
, Q3 Question 3 of 75
A 72-year-old client with renal impairment is prescribed a medication that is primarily
excreted by the kidneys. The nurse understands that the prescriber will likely make
which adjustment to prevent drug accumulation?
A. Increase the frequency of administration
B. Decrease the dosage or extend the dosing interval
C. Switch to an intravenous route
D. Add a hepatic enzyme inducer
Correct Answer: B
Rationale:
In renal impairment, drugs excreted by the kidneys accumulate in the body because clearance is
reduced. The appropriate adjustment is to decrease the dosage or extend the dosing interval to maintain
therapeutic levels without causing toxicity.
Q4 Question 4 of 75
A nurse is reviewing a client's medication list and notes that the client is taking both
warfarin and aspirin. The nurse recognizes that this combination places the client at
increased risk for which complication?
A. Gastrointestinal bleeding
B. Thrombocytosis
C. Hypercoagulability
D. Hypoglycemia
Correct Answer: A
Rationale:
Both warfarin and aspirin affect clotting mechanisms. Warfarin inhibits vitamin K-dependent clotting
factors, while aspirin inhibits platelet aggregation. Concurrent use significantly increases the risk of
bleeding, particularly gastrointestinal bleeding.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 2 of 4
, Q5 Question 5 of 75
A 55-year-old client is prescribed a medication that is a cytochrome P450 enzyme
inducer. The nurse understands that this medication may cause which effect on other
drugs metabolized by the same enzyme system?
A. Increased therapeutic effects of other drugs
B. Decreased therapeutic effects of other drugs
C. Increased risk of allergic reactions
D. Prolonged half-life of other drugs
Correct Answer: B
Rationale:
Cytochrome P450 enzyme inducers increase the metabolism of other drugs that use the same pathway.
This leads to decreased plasma concentrations and reduced therapeutic effects of those drugs,
potentially causing treatment failure.
Q6 Question 6 of 75
A nurse is calculating a medication dosage for a 3-year-old child using the body
surface area (BSA) method. The child's BSA is 0.52 m . The adult dose is 500 mg.
What is the appropriate child's dose using the standard BSA formula?
A. 100 mg
B. 150 mg
C. 200 mg
D. 250 mg
Correct Answer: B
Rationale:
The standard BSA formula for pediatric dosing is: Child's dose = (Child's BSA / 1.73 m ) Adult dose. For
this child: (0..73) 500 = 0.3006 500 = 150.3 mg, which rounds to 150 mg.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 2 of 4
OBJECTIVE ASSESSMENT - EXAM
ATI PN Pharmacology Proctor
Exam | 2026/2027 NGN-Style
Questions & Case Studies |
Pharmacology ATI (PDF)
2026/2027
PN Proctored Assessment | NGN-Aligned
75 100%
QUESTIONS VERIFIED ANSWERS EDITION
TOPICS COVERED
Drug Classifications & Mechanisms of Action Neurological & Psychiatric Medications
Cardiovascular Pharmacology Endocrine & Metabolic Agents
Respiratory Medications Anti-Infective & Immune Therapy
COVER PAGE - 1
, SECTION 1 | Pharmacology Basics | Q1-Q75 | ATI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Q
Q1 Question 1 of 75
A 68-year-old client is prescribed digoxin 0.25 mg orally daily. The nurse reviews the
client's medication history and notes the client also takes furosemide 40 mg daily.
The nurse recognizes that concurrent use of these medications increases the risk of
which adverse effect?
A. Hyperkalemia
B. Digoxin toxicity
C. Hypotension
D. Bradycardia
Correct Answer: B
Rationale:
Furosemide is a loop diuretic that causes potassium depletion. Hypokalemia increases the risk of
digoxin toxicity because low potassium levels enhance digoxin binding to cardiac tissue. The nurse
should monitor potassium levels closely.
Q2 Question 2 of 75
A nurse is preparing to administer a medication via the intramuscular route to a
45-year-old client. The nurse selects the ventrogluteal site and plans to insert the
needle at which angle?
A. 15 degrees
B. 45 degrees
C. 90 degrees
D. 30 degrees
Correct Answer: C
Rationale:
The ventrogluteal site is the preferred intramuscular injection site for adults because it is free of major
nerves and blood vessels. The needle should be inserted at a 90-degree angle to reach the muscle
tissue.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 2 of 4
, Q3 Question 3 of 75
A 72-year-old client with renal impairment is prescribed a medication that is primarily
excreted by the kidneys. The nurse understands that the prescriber will likely make
which adjustment to prevent drug accumulation?
A. Increase the frequency of administration
B. Decrease the dosage or extend the dosing interval
C. Switch to an intravenous route
D. Add a hepatic enzyme inducer
Correct Answer: B
Rationale:
In renal impairment, drugs excreted by the kidneys accumulate in the body because clearance is
reduced. The appropriate adjustment is to decrease the dosage or extend the dosing interval to maintain
therapeutic levels without causing toxicity.
Q4 Question 4 of 75
A nurse is reviewing a client's medication list and notes that the client is taking both
warfarin and aspirin. The nurse recognizes that this combination places the client at
increased risk for which complication?
A. Gastrointestinal bleeding
B. Thrombocytosis
C. Hypercoagulability
D. Hypoglycemia
Correct Answer: A
Rationale:
Both warfarin and aspirin affect clotting mechanisms. Warfarin inhibits vitamin K-dependent clotting
factors, while aspirin inhibits platelet aggregation. Concurrent use significantly increases the risk of
bleeding, particularly gastrointestinal bleeding.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 2 of 4
, Q5 Question 5 of 75
A 55-year-old client is prescribed a medication that is a cytochrome P450 enzyme
inducer. The nurse understands that this medication may cause which effect on other
drugs metabolized by the same enzyme system?
A. Increased therapeutic effects of other drugs
B. Decreased therapeutic effects of other drugs
C. Increased risk of allergic reactions
D. Prolonged half-life of other drugs
Correct Answer: B
Rationale:
Cytochrome P450 enzyme inducers increase the metabolism of other drugs that use the same pathway.
This leads to decreased plasma concentrations and reduced therapeutic effects of those drugs,
potentially causing treatment failure.
Q6 Question 6 of 75
A nurse is calculating a medication dosage for a 3-year-old child using the body
surface area (BSA) method. The child's BSA is 0.52 m . The adult dose is 500 mg.
What is the appropriate child's dose using the standard BSA formula?
A. 100 mg
B. 150 mg
C. 200 mg
D. 250 mg
Correct Answer: B
Rationale:
The standard BSA formula for pediatric dosing is: Child's dose = (Child's BSA / 1.73 m ) Adult dose. For
this child: (0..73) 500 = 0.3006 500 = 150.3 mg, which rounds to 150 mg.
TI PN Pharmacology Proctor Exam | 2026/2027 NGN-Style Questions & Case Studies | Pharmacology ATI (PDF) 2026/2027 -- 2026/2027 | Passing Score: 80% | Page 2 of 4
