--
TEST BANK FOR: MCCANCE:
PATHOPHYSIOLOGY THE BIOLOGIC
BASIS FOR DISEASE IN ADULTS &
CHILDREN 8TH EDITION BY KATHRYN
L MCCANCE, SUE E HUETHER –ISBN-
13;978-0275972486
PATHOPHYSIOLOGY THE BIOLOGIC BASIS FOR DISEASE IN ADULTS & CHILDREN 8TH EDITION
,--
PATHOPHYSIOLOGY THE BIOLOGIC BASIS FOR DISEASE IN ADULTS & CHILDREN 8 TH EDITION
,--
CHAPTER 01: CELLULAR BIOLOGY
MULTIPLE CHOICE
1. Which statement best describes the cellular function of metabolic absorption?
a. Cells can produce proteins.
b. Cells can secrete digestive
enzymes.
c. Cells can take in and use
nutrients.
d. Cells can synthesize fats.
ANS: C
In metabolic absorption, all cells take in and use nutrients and other substances
from their surroundings. The remaining options are not inclusive in their
descriptions of cellular metabolic absorption.
PTS: 1 DIF: Cognitive Level: Remembering
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
a. Mitochondr
ia
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: C
The nucleus contains the nucleolus, a small dense structure composed
largely of RNA, most of the cellular DNA, and the DNA-binding proteins, such
as the histones, which regulate its activity. The mitochondria are responsible
for cellular respiration and energy production.
Ribosomes’ chief function is to provide sites for cellular protein synthesis.
Lysosomes function as the intracellular digestive system.
PTS: 1 DIF: Cognitive Level: Remembering
3. Which component of the cell produces hydrogen peroxide (H2O2) by using
oxygen to remove hydrogen atoms from specific substrates in an oxidative
reaction?
a. Lysosomes
b. Peroxisom
es
c. Ribosomes
d. Endosome
ANS: B
PATHOPHYSIOLOGY THE BIOLOGIC BASIS FOR DISEASE IN ADULTS & CHILDREN 8 TH EDITION
, --
Peroxisomes are so named because they usually contain enzymes that use
oxygen to remove hydrogen atoms from specific substrates in an oxidative
reaction that produces H2O2, which is a powerful oxidant and potentially
destructive if it accumulates or escapes from peroxisomes.
Ribosomes are RNA-protein complexes (nucleoproteins) that are synthesized
in the nucleolus and secreted into the cytoplasm through pores in the nuclear
envelope called nuclear pore complexes. Lysosomes are saclike structures that
originate from the Golgi complex and contain more than 40 digestive enzymes
called hydrolases, which catalyze bonds in proteins, lipids, nucleic acids, and
carbohydrates. An endosome is a vesical that has been pinched off from the
cellular membrane.
PTS: 1 DIF: Cognitive Level: Remembering
4. Which cell component is capable of cellular autodigestion when it is released
during cell injury?
a. Ribosome
b. Golgi complex
c. Smooth endoplasmic
reticulum
d. Lysosomes
ANS: D
The lysosomal membrane acts as a protective shield between the powerful
digestive enzymes within the lysosome and the cytoplasm, preventing their
leakage into the cytoplasmic matrix. Disruption of the membrane by various
treatments or cellular injury leads to a release of the lysosomal enzymes,
which can then react with their specific substrates, causing cellular self-
digestion. The chief function of a ribosome is to provide sites for cellular
protein synthesis. The Golgi complex is a network of flattened, smooth vesicles
and membranes often located near the cell nucleus. The smooth endoplasmic
reticulum is involved in steroid hormone production and removing toxic
substances from the cell.
PTS: 1 DIF: Cognitive Level: Remembering
5. Which cAMP-mediated response is related to antidiuretic hormone?
a. Increased heart rate and force of
contraction
b. Secretion of cortisol
c. Increased retention of water
d. Breakdown of fat
ANS: C
Antidiuretic hormone leads to increased retention of water in the body.
Epinephrine causes increases in heart rate and force of contraction.
Increased cortisol secretion is due to ACTH. Breakdown of fat is due to
glucagon.
PTS: 1 DIF: Cognitive Level: Remembering
PATHOPHYSIOLOGY THE BIOLOGIC BASIS FOR DISEASE IN ADULTS & CHILDREN 8 TH EDITION
TEST BANK FOR: MCCANCE:
PATHOPHYSIOLOGY THE BIOLOGIC
BASIS FOR DISEASE IN ADULTS &
CHILDREN 8TH EDITION BY KATHRYN
L MCCANCE, SUE E HUETHER –ISBN-
13;978-0275972486
PATHOPHYSIOLOGY THE BIOLOGIC BASIS FOR DISEASE IN ADULTS & CHILDREN 8TH EDITION
,--
PATHOPHYSIOLOGY THE BIOLOGIC BASIS FOR DISEASE IN ADULTS & CHILDREN 8 TH EDITION
,--
CHAPTER 01: CELLULAR BIOLOGY
MULTIPLE CHOICE
1. Which statement best describes the cellular function of metabolic absorption?
a. Cells can produce proteins.
b. Cells can secrete digestive
enzymes.
c. Cells can take in and use
nutrients.
d. Cells can synthesize fats.
ANS: C
In metabolic absorption, all cells take in and use nutrients and other substances
from their surroundings. The remaining options are not inclusive in their
descriptions of cellular metabolic absorption.
PTS: 1 DIF: Cognitive Level: Remembering
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
a. Mitochondr
ia
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: C
The nucleus contains the nucleolus, a small dense structure composed
largely of RNA, most of the cellular DNA, and the DNA-binding proteins, such
as the histones, which regulate its activity. The mitochondria are responsible
for cellular respiration and energy production.
Ribosomes’ chief function is to provide sites for cellular protein synthesis.
Lysosomes function as the intracellular digestive system.
PTS: 1 DIF: Cognitive Level: Remembering
3. Which component of the cell produces hydrogen peroxide (H2O2) by using
oxygen to remove hydrogen atoms from specific substrates in an oxidative
reaction?
a. Lysosomes
b. Peroxisom
es
c. Ribosomes
d. Endosome
ANS: B
PATHOPHYSIOLOGY THE BIOLOGIC BASIS FOR DISEASE IN ADULTS & CHILDREN 8 TH EDITION
, --
Peroxisomes are so named because they usually contain enzymes that use
oxygen to remove hydrogen atoms from specific substrates in an oxidative
reaction that produces H2O2, which is a powerful oxidant and potentially
destructive if it accumulates or escapes from peroxisomes.
Ribosomes are RNA-protein complexes (nucleoproteins) that are synthesized
in the nucleolus and secreted into the cytoplasm through pores in the nuclear
envelope called nuclear pore complexes. Lysosomes are saclike structures that
originate from the Golgi complex and contain more than 40 digestive enzymes
called hydrolases, which catalyze bonds in proteins, lipids, nucleic acids, and
carbohydrates. An endosome is a vesical that has been pinched off from the
cellular membrane.
PTS: 1 DIF: Cognitive Level: Remembering
4. Which cell component is capable of cellular autodigestion when it is released
during cell injury?
a. Ribosome
b. Golgi complex
c. Smooth endoplasmic
reticulum
d. Lysosomes
ANS: D
The lysosomal membrane acts as a protective shield between the powerful
digestive enzymes within the lysosome and the cytoplasm, preventing their
leakage into the cytoplasmic matrix. Disruption of the membrane by various
treatments or cellular injury leads to a release of the lysosomal enzymes,
which can then react with their specific substrates, causing cellular self-
digestion. The chief function of a ribosome is to provide sites for cellular
protein synthesis. The Golgi complex is a network of flattened, smooth vesicles
and membranes often located near the cell nucleus. The smooth endoplasmic
reticulum is involved in steroid hormone production and removing toxic
substances from the cell.
PTS: 1 DIF: Cognitive Level: Remembering
5. Which cAMP-mediated response is related to antidiuretic hormone?
a. Increased heart rate and force of
contraction
b. Secretion of cortisol
c. Increased retention of water
d. Breakdown of fat
ANS: C
Antidiuretic hormone leads to increased retention of water in the body.
Epinephrine causes increases in heart rate and force of contraction.
Increased cortisol secretion is due to ACTH. Breakdown of fat is due to
glucagon.
PTS: 1 DIF: Cognitive Level: Remembering
PATHOPHYSIOLOGY THE BIOLOGIC BASIS FOR DISEASE IN ADULTS & CHILDREN 8 TH EDITION
